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Diagnosis and treatment of interstitial lung disease: focusing on idiopathic pulmonary fibrosis

Kang HR, Choi SM

Interstitial lung disease (ILD) is a rare condition characterized by extensive inflammation and fibrosis mainly involving the pulmonary interstitium or alveoli. Usually, patients with ILD clinically present with chronic cough...
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The Clinical Efficacy of Pulmonary Hypertension-Specific Agents in Idiopathic Pulmonary Fibrosis: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

Lee J, Song JU

BACKGROUND: Pulmonary hypertension (PH) is common in patients with idiopathic pulmonary fibrosis (IPF) and is associated with poor outcomes. This study was performed to determine the clinical efficacy of PH-specific...
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Pharmacological treatment of pulmonary fibrosis

Choi WI

Idiopathic pulmonary fibrosis (IPF) is a condition that has been described as alveolar collapse and thickening, which correlate with dysregulated surfactant production and injury to type 2 alveolar cells. As...
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Deficiency of Sphingosine-1-Phosphate Receptor 2 (S1Pâ‚‚) Attenuates Bleomycin-Induced Pulmonary Fibrosis

Park SJ, Im DS

Sphingosine 1-phosphate (S1P) levels are often found to be elevated in serum, bronchoalveolar lavage, and lung tissue of idiopathic pulmonary fibrosis patients and experimental mouse models. Although the roles of...
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Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 2. Idiopathic Pulmonary Fibrosis

Lee SH, Yeo Y, Kim TH, Lee HL, Lee JH, Park YB, Park JS, Kim YH, Song JW, Jhun BW, Kim HJ, Park J, Uh ST, Kim YW, Kim DS, Park MS, Korean Interstitial Lung Diseases Study Group

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial pneumonia, which presents with a progressive worsening dyspnea, and thus a poor outcome. The members of the Korean Academy of...
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New Diagnostic Guidelines for Idiopathic Pulmonary Fibrosis

Kwon BS, Song JW

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease characterized by worsening lung function and dyspnea. The prognosis of IPF patients is poor, as median survival is approximately...
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Extracorporeal Membrane Oxygenation Bridge to Lung Transplantation in a Patient with Hermansky-Pudlak Syndrome and Progressive Pulmonary Fibrosis

Sim W, Kim SY, Han J, Rim TH, Lee JG, Paik HC, Park MS

No abstract available.
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A review of current studies on cellular and molecular mechanisms underlying pulmonary fibrosis induced by chemicals

Kim HR, Shin DY, Chung KH

Several studies showed that the inflammatory and fibrotic responses induced by polyhexamethylene guanidine phosphate (PHMG-p) were similar to those observed for idiopathic pulmonary fibrosis in South Korea in 2011. “Omic”...
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Abnormal Bolus Reflux Is Associated With Poor Pulmonary Outcome in Patients With Idiopathic Pulmonary Fibrosis

Borges LF, Jagadeesan V, Goldberg H, Gavini S, Lo WK, Burakoff R, Feldman N, Chan WW

  • KMID: 2417383
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):395-402.
  • doi: 10.5056/jnm18023
BACKGROUND/AIMS: Gastroesophageal reflux (GER) is postulated to play a role in idiopathic pulmonary fibrosis (IPF). However, the value of objective GER measures in predicting IPF disease progression is unclear. We...
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Pirfenidone-Induced Photosensitivity in a Patient with Idiopathic Pulmonary Fibrosis

Kim HJ, Seo JW, Kim TH, Choi SH, Song KH, Kim KH

No abstract available.
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Protective Effect of Proton Pump Inhibitor for Survival in Patients with Gastroesophageal Reflux Disease and Idiopathic Pulmonary Fibrosis

Lee CM, Lee DH, Ahn BK, Hwang JJ, Yoon H, Shin CM, Park YS, Kim N

  • KMID: 2327949
  • J Neurogastroenterol Motil.
  • 2016 Jul;22(3):444-451.
  • doi: 10.5056/jnm15192
BACKGROUND/AIMS: The prevalence of gastroesophageal reflux disease (GERD) is high in patients with idiopathic pulmonary fibrosis (IPF). GERD may cause chronic microaspiration that leads to repeated subclinical lung injury, which...
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Human Adipose-derived Mesenchymal Stem Cells Attenuate Early Stage of Bleomycin Induced Pulmonary Fibrosis: Comparison with Pirfenidone

Reddy M, Fonseca L, Gowda S, Chougule B, Hari A, Totey S

BACKGROUND AND OBJECTIVES: Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible, invariably fatal fibrotic lung disease with no lasting option for therapy. Mesenchymal stem cells (MSCs) could be a promising...
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Pathophysiological Studies Are Mandatory to Understand the Benefit of Proton Pump Inhibitors in Patients with Idiopathic Pulmonary Fibrosis

Savarino E, Zentilin P, Marabotto , Savarino V

  • KMID: 2433467
  • J Neurogastroenterol Motil.
  • 2016 Oct;22(4):710-711.
  • doi: 10.5056/jnm16120
No abstract available.
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Amelioration of Bleomycin-induced Pulmonary Fibrosis of Rats by an Aldose Reductase Inhibitor, Epalrestat

Li X, Shen Y, Lu Y, Yang J

Aldose reductase (AR) is known to play a crucial role in the mediation of diabetic and cardiovascular complications. Recently, several studies have demonstrated that allergen-induced airway remodeling and ovalbumin-induced asthma...
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Polyarteritis Nodosa Associated with Interstitial Pulmonary Fibrosis

Kim JH, Shin MK

  • KMID: 2246230
  • Korean J Dermatol.
  • 2015 Feb;53(2):144-147.
Classic polyarteritis nodosa (PAN) involves small-to-medium-sized muscular arteries in multiple organ systems. It presents in combination with skin diseases, myalgia, hypertension, abdominal pain, or neuropathy. Although PAN involves the muscles,...
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Two Successfully Treated Cases of Pulmonary Fibrosis Due to Paraquat Poisoning

Lee WK, Seong CS, Kim BS, Choi HM, Lee HS, Yoon HJ, Kim JG, Lee MS, Lee KY, Sun IO

Paraquat poisoning can cause severe multiple organ failure involving the kidneys, liver, lungs, adrenals, and central nervous system. The toxic effect of paraquat on the lung manifests as pulmonary edema,...
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Dual Extracorporeal Membrane Oxygenation Support for Bridging Lung Transplantation in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Kim DJ, Lee YJ, Kim JS, Park S, Cho YJ

When patients with severe respiratory failure are treated with venovenous extracorporeal membrane oxygenation (VV-ECMO), severe pulmonary hypertension due to right ventricular (RV) failure is possible. This is a serious complication...
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Annual Change in Pulmonary Function and Clinical Characteristics of Combined Pulmonary Fibrosis and Emphysema and Idiopathic Pulmonary Fibrosis: Over a 3-Year Follow-up

Kim YJ, Shin SH, Park JW, Kyung SY, Kang SM, Lee SP, Sung YM, Kim YK, Jeong SH

  • KMID: 2320533
  • Tuberc Respir Dis.
  • 2014 Jul;77(1):18-23.
BACKGROUND: Combined pulmonary fibrosis and emphysema (CPFE) have different pulmonary function tests (PFTs) and outcomes than idiopathic pulmonary fibrosis (IPF). The intention of this study was to identify unknown differences...
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Histolgical AND Immunohistochemical Study on the Effect of Stem Cell Therapy on Bleomycin Induced Pulmonary Fibrosis in Albino Rat

Sabry MM, Elkalawy S, Abo-Elnour RKEd, Abd-El-Maksod DF

  • KMID: 2054558
  • Int J Stem Cells.
  • 2014 May;7(1):33-42.
AIM OF WORK: To demonstrate the bleomycin induced histological changes in the lung and the possible protective and/or therapeutic effect of stem cell therapy. MATERIALS AND METHODS: Study was carried out...
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Usual Interstitial Pneumonia with Lung Cancer: Clinicopathological Analysis of 43 Cases

Song DH, Choi IH, Ha SY, Han KM, Lee JJ, Hong ME, Jeon K, Chung MP, Kim J, Han J

  • KMID: 1875752
  • Korean J Pathol.
  • 2014 Feb;48(1):10-16.
BACKGROUND: Previous studies have suggested an association between usual interstitial pneumonia (UIP) and lung cancer (Ca). However, clinical and histological information is not enough to determine such an association, due...
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