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Dopamine and serotonin alterations by Hizikia fusiformis extracts under in vitro cortical primary neuronal cell cultures

Jung JW, Kim YJ, Choi JS, Goto Y, Lee YA

BACKGROUND/OBJECTIVES:Hizikia fusiformis (HF) is a class of brown seaweeds whose active ingredients exert central nervous system protective effects, such as neuroprotection; however, the underlying mechanisms remain unknown. Given that dopamine (DA)...
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Practical Issues With Clonazepam Use

Kang UG, Kim SH, Choi YS, Lee KY, Kim YS, Chung IW

Clonazepam, a 7-nitrobenzodiazepine, has been used for the treatment of various neuropsychiatric disorders such as seizures, sleep disorders, panic disorders, anxiety, and movement disorders. However, clonazepam is officially approved as...
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Benzodiazepines: Pharmacology Up-to-Date and Practical Issues

Kang UG, Kim SH, Lee NY, Lee KY, Kim YS, Chung IW

Benzodiazepines have been widely used as anxiolytics, sedatives, hypnotics, anticonvulsants, or central muscle relaxants since the 1960s despite significant adverse effects, the potential for misuse, and consequent overdose. Benzodiazepines exert...
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Suicide Method, the Recent Stressors, Psychiatric Diagnosis of Suicide Attempters and Suicide Completers

O SH, Ahn J, Jihyo S, Gu H, Kim M, Jang H, Kim SJ

Objectives: Suicide is the major public mental health concerns all over the world. The comparison of suicide attempters and suicide completers could be the fundamental evidence for the suicide prevention....
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Anesthetic care for electroconvulsive therapy

Joung KW, Park DH, Jeong CY, Yang HS

Counselling and medication are often thought of as the only interventions for psychiatric disorders, but electroconvulsive therapy (ECT) has also been applied in clinical practice for over 80 years. ECT...
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A Systematic Review on Cognitive Effects of Electroconvulsive Therapy in Asian Patients

Ong Y, Chan LG

Objective: Electroconvulsive therapy (ECT) is the most efficacious treatment for many major mental illnesses but is limited by cognitive side effects. However, research on the pattern and severity of ECT-related...
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Effectiveness of Short-Term Psychodynamic Psychotherapy in Preadolescents and Adolescents Affected by Psychiatric Disorders

Mensi MM, Orlandi M, Rogantini C, Borgatti R, Chiappedi M

Objective Few studies have explored the effectiveness of short-term psychodynamic psychotherapy in children and adolescents. We aimed to investigate its efficacy in a heterogeneous group of young patients. We also...
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Acute Impact of the Coronavirus Disease Outbreak on Behavioral Patterns and Emotional States of Pediatric Psychiatric Patients and Caregivers in Daegu, South Korea

Seo HR, Jung HS, Jung DS, Choi JW, Jo SH

Objective This study aimed to investigate the changes in interpersonal relationships, behavioral patterns, and emotional states of children and adolescents with psychiatric disorders and their caregivers immediately after the coronavirus...
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Systematic Literature Review of Psychiatric Comorbidities in Adults with Epilepsy

Lu E, Pyatka N, Burant CJ, Sajatovic M

Background and Purpose Mental illness is disproportionately common in people with epilepsy (PWE). This systematic literature review identified original research articles that reported the prevalence of psychiatric comorbidities based upon...
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Analysis of Circadian Rhythms in the Research of Psychiatric Disorders

Kim SY, Moon E, Jeong HJ

  • KMID: 2513150
  • J Korean Soc Biol Ther Psychiatry.
  • 2021 Feb;27(1):5-11.
In the field of psychiatry, studies on circadian rhythms are increasing. This research trend is based on the emerging evidence on the relationship between circadian rhythm and pathophysiology and prognosis...
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Anxiety, depression, and stress in Korean patients with chronic urticaria

Choi GS, Nam YH, Park CS, Kim MY, Jo EJ, Park HK, Kim HK

Background/Aims: Emotional distress is thought to cause or maintain chronic urticaria (CU). We aimed to investigate the presence of anxiety, depression, and stress in Korean adult CU patients and to...
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Measurement of Circadian Rhythms in the Research of Psychiatric Disorders

Kim SY, Moon E, Jeong HJ

  • KMID: 2508331
  • J Korean Soc Biol Ther Psychiatry.
  • 2020 Oct;26(3):177-183.
The circadian rhythms have been gradually important in psychiatric field. Several studies have shown that major psychiatric disorders, such as schizophrenia, bipolar disorders, and dementia, were highly associated with the...
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Adverse Effect of Exposure to Ambient Particular Matter on Neuropsychiatric Disorder

Lim MH, Kim JH, Kwon HJ, Cheong HK

Particular matter is steadily increasing due to environmental factors at domestic and abroad such as industry and economy. Recently, the exposure particular matters has been reported to increase the risk...
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Patterns of the Diagnosis Prevalence of Psychiatric Disorders in the Population Aged 0–18 Years Ba

Lee SY, Bahn GH

  • KMID: 2507493
  • J Korean Acad Child Adolesc Psychiatry.
  • 2020 Oct;31(4):214-224.
  • doi: 10.5765/jkacap.200017
Objectives: This study aimed to examine the trend in diagnostic prevalence of psychiatric disorders in children and adolescents. Methods: Individuals aged 0–18 years were included in the study based on the...
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Rodent models for psychiatric disorders: problems and promises

Baker M, Hong SI, Kang S, Choi DS

Psychiatric disorders are a prevalent global health problem, over 900 million individuals affected by a continuum of mental and substance use disorders. Due to this high prevalence, and the substantial...
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Diagnostic Distribution of Psychiatric Disorders among Korean Young Adults

Hwangbo R, Chang H, Bahn GH

Objectives: The prevalence of psychiatric disorders among young adults is different from that among younger or older age groups because of biological and environmental changes. The purpose of this study...
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From Bound Cells Comes a Sound Mind: The Role of Neuronal Growth Regulator 1 in Psychiatric Disorders

Noh K, Park JC, Han JS, Lee SJ

Cell-to-cell adhesion is important for maintenance of brain structure and function. Abnormal neuronal cell adhesion and loss of its connectivity are considered a main cause of psychiatric disorders such as...
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Skin Diseases in Patients with Primary Psychiatric Disorders

Mavrogiorgou P, Mersmann C, Gerlach G, Herpertz S, Juckel G

Objective The few psychodermatological studies of primary psychiatric populations so far suggest that parasitic-infectious skin diseases are the most common dermatological comorbidity in more than 70% of psychiatric patients, which...
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Recapitulation of Neuropsychiatric Behavioral Features in Mice Using Acute Low-dose MK-801 Administration

Mabunga DF, Park D, Ryu O, Valencia S, Adil KJ, Kim S, Kwon KJ, Shin CY, Jeon SJ

Despite some innate limitations, animal models are a potent investigative tool when used to model specific symptoms of a disorder. For example, MK-801, an N-methyl-D-aspartate receptor antagonist, is used as...
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Neuropsychiatric Symptoms of Multiple Sclerosis: State of the Art

Silveira C, Guedes R, Maia D, Curral R, Coelho R

Multiple Sclerosis (MS) is a chronic disabling neuroinflammatory disease. Psychiatric manifestations have a high prevalence in MS patients and may worsen the illness progression and the patients’ quality of life...
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