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Mechanism of Actions and Clinical Applications of Proton Pump Inhibitors

Seol SY

  • KMID: 782731
  • Korean J Gastroenterol.
  • 2006 Jul;48(1):4-8.
Proton pump inhibitors (PPIs) are widely used in clinical practice from early 1990s for the treatment of acid- related diseases. PPIs are superior to histamine2-receptor antagonists or anticholinergic agents. These...
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Clinical Use of Proton Pump Inhibitors in Gastrointestinal Diseases

Rew JS

  • KMID: 1113451
  • Korean J Gastroenterol.
  • 2006 Mar;47(3):181-190.
The development and introduction into clinical practice of proton pump inhibitors (PPIs) have influenced the management of acid-peptic disorders dramatically. PPIs inhibit the gastric hydrogen/potassium adenosine triphosphatase selectively and irreversibly...
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Treatment of Helicobacter pylori Infection

Kim JG

  • KMID: 935208
  • Korean J Gastroenterol.
  • 2005 Sep;46(3):172-180.
Significant progress and new insights have been gained since Helicobacter pylori was found in 1982. Even with currently most effective treatment regimen, about 10-20% of patients will fail to obtain...
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Comparison of Helicobacter pylori Eradication Rate according to Different PPI-based Triple Therapy : Omeprazole, Rabeprazole, Esomeprazole and Lansoprazole

Keum B, Lee SW, Kim SY, Kim MJ, Choung RS, Yim HJ, Jeen YT, Lee HS, Chun HJ, Um SH, Choi JH, Kim CD, Ryu HS, Hyun JH

  • KMID: 935193
  • Korean J Gastroenterol.
  • 2005 Dec;46(6):433-439.
BACKGROUND/AIMS: Helicobacter pylori (H. pylori) is an important cause of various gastrointestinal diseases. H. pylori eradication is essential for the cure and prevention of associated diseases. Nowdays, proton pump inhibitor...
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Efficacy of Triple Therapy with Rabeprazole for Helicobacter pylori Infection in relation to CYP2C19 Genotype

Lee SB, Park SJ, Ryu JK, Lee JK, Kim HJ, Bae JS, Jung HS, Park SM

  • KMID: 1066037
  • Korean J Gastroenterol.
  • 2003 Dec;42(6):468-475.
BACKGROUND/AIMS: Genetic polymorphism of cytochrome P450 CYP2C19 influences the efficacy of proton pump inhibitor (PPI) in Helicobacter pylori (H. pylori) eradication therapy. We investigated the difference in the cure...
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A Randomized, Prospective, Comparative, Multicenter Study of Rabeprazole and Ranitidine in the Treatment of Reflux Esophagitis

Jeong HY, Lee BS, Sung JK, Lee TY, Yoon SJ, Kim SJ, Chung IK, Lee SH, Shin JE, Lee DS, Baek JT, Nam SW, Yoon SJ, Kim SH, Lee GS, Lee JM, Kim AN, Oh JI

  • KMID: 1079899
  • Korean J Gastroenterol.
  • 2006 Jan;47(1):15-21.
BACKGROUND/AIMS: This study was done to evaluate the efficacy of rabeprazole (proton-pump-inhibitor) and ranitidine (H2-receptor antagonist) in the symptom relief and treatment of erosive esophagitis diagnosed by endoscopy. METHODS:...
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