- 5' CpG island methylation of p16 is associated with absence of p16 expression in glioblastomas
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Park SH, Jung KC, Ro JY, Kang GH, Khang SK
- KMID: 965879
- J Korean Med Sci.
- 2000 Oct;15(5):555-559.
- doi: 10.3346/jkms.2000.15.5.555
Recent evidence shows that transcriptional silencing as a consequence of hypermethylation of CpG islands is an important mechanism in the inactivation of p16INK4 tumor suppressor gene. This study is designed... -
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- Expression of the G1-S Modulators in Hepatitis B Virus-Related Hepatocellular Carcinoma and Dysplastic Nodule: Association of Cyclin D1 and p53 Proteins with the Progression of Hepatocellular Carcinoma
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Choi YL, Park SH, Jang JJ, Park CK
- KMID: 648300
- J Korean Med Sci.
- 2001 Aug;16(4):424-432.
- doi: 10.3346/jkms.2001.16.4.424
Deranged expression of cell cycle modulators has been reported to contribute to the development and progression of hepatocellular carcinoma (HCC). However, their expression patterns remain poorly understood in hepatitis B... -
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- Alteration of Cell Cycle in Cervical Tumor Associated with Human Papillomavirus: Cyclin-Dependent Kinase Inhibitors
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Cho NH, Kim YT, Kim JW
- KMID: 1093947
- Yonsei Med J.
- 2002 Dec;43(6):722-728.
- doi: 10.3349/ymj.2002.43.6.722
The ability of viral oncoproteins to subvert cell cycle checkpoints may constitute a mechanism by which viral oncoproteins induce genetic instability. HPV 16 E6 and E7 disrupt cell cycle checkpoints,... -
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