- Protein Methylation and Interaction with the Antiproliferative Gene, BTG2(/TIS21/Pc3)
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Paik WK, Kim S, Lim IK
- KMID: 2386454
- Yonsei Med J.
- 2014 Mar;55(2):292-303.
The last one and half a decade witnessed an outstanding re-emergence of attention and remarkable progress in the field of protein methylation. In the present article, we describe the early... -
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- Protein methylation in cellular proliferation and differentiation: Non-histone nuclear methyl acceptor protein(s) during 3'-methyl-4-dimethylaminoazobenzeneinduced hepatocarcinogenesis
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Paik MK, Han YJ, Hong JH, Kim JS, Suh KS, Yoon SJ
- KMID: 2128624
- Exp Mol Med.
- 1997 Mar;29(1):35-43.
An accelerating effect of methyl-deficient diet (MDD) on hepatocarcinogenesis and methylation pattern of nuclear protein(s) by S-adenosylmethionine: protein arginine N-methyltransferase (protein methylase I, PM-I) have been studied with 3'-methyl-4-dimethyl- aminoazobenzene(MeDAB)-treated... -
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- Enzymology of Protein Methylation
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Paik WK, Kim S
- KMID: 693029
- Yonsei Med J.
- 1986 Sep;27(3):159-177.
- doi: 10.3349/ymj.1986.27.3.159
No abstract available. -
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- Partial purification of protein farnesyl cysteine carboxyl methyltransferase from bovine brain
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Yoo BC, Kang MS, Kim SD, Lee YS, Choi SY, Ryu CK, Park GH, Han JS
- KMID: 755013
- Exp Mol Med.
- 1998 Dec;30(4):227-234.
C-terminal farnesyl cysteine carboxyl methylation has been known to be the last step in the post-translational modification processes of several important signal transduction proteins in eukaryotes including ras related GTP... -
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- Cysteine carboxyl O-methylation of human placental 23 kDa protein
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Hong KM, Choi YB, Hong JH, Chang HS, Rhee KI, Park H, Paik MK
- KMID: 755024
- Exp Mol Med.
- 1999 Mar;31(1):30-35.
C-Terminal carboxyl methylation of a human placental 23 kDa protein catalyzed by membrane-associated methyltransferase has been investigated. The 23 kDa protein substrate methylated was partially purified by DEAE-Sephacel, hydroxyapatite and Sephadex G-100 gel... -
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- Methylation of eukaryotic elongation factor 2 induced by basic fibroblast growth factor via mitogen-activated protein kinase
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Jung GA, Shin BS, Jang YS, Sohn JB, Woo SR, Kim JE, Choi G, Lee KM, Min BH, Lee KH, Park GH
- KMID: 1123367
- Exp Mol Med.
- 2011 Oct;43(10):550-560.
- doi: 10.3858/emm.2011.43.10.061
Protein arginine methylation is important for a variety of cellular processes including transcriptional regulation, mRNA splicing, DNA repair, nuclear/cytoplasmic shuttling and various signal transduction pathways. However, the role of arginine... -
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- The functional role of the CARM1-SNF5 complex and its associated HMT activity in transcriptional activation by thyroid hormone receptor
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Choi HK, Choi KC, Oh SY, Kang HB, Lee YH, Haam S, Ahn YH, Kim KS, Kim K, Yoon HG
- KMID: 756078
- Exp Mol Med.
- 2007 Aug;39(4):544-555.
We have investigated the function and mechanisms of the CARM1-SNF5 complex in T3-dependent transcriptional activation. Using specific small interfering RNAs (siRNA) to knock down coactivators in HeLa alpha2 cells, we... -
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