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Negative Regulation of Intracellular Cytokine Signal Transduction

Ji JD, Lee YH, Song GG

  • KMID: 1618560
  • J Korean Rheum Assoc.
  • 2003 Mar;10(1):1-8.
Cytokines are secreted proteins and interact with their specific cell surface receptors, triggering intracellular signal transduction pathways that activate a number of genes crucial for the biological functions of cytokines....
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PIAS1 interacts with the KRAB zinc finger protein, ZNF133, via zinc finger motifs and regulates its transcriptional activity

Lee SJ, Lee JR, Hah HS, Kim YH, Ahn JH, Bae CD, Yang JM, Hahn MJ

  • KMID: 756067
  • Exp Mol Med.
  • 2007 Aug;39(4):450-457.
Zinc finger protein 133 (ZNF133) is composed of a Kruppel-associated box (KRAB) domain and 14 contiguous zinc finger motifs. ZNF133 is regarded as a transcriptional repressor because the KRAB domain...
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