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Efficacy of Bacteriophages in Propionibacterium acnes-Induced Inflammation in Mice

Kim MJ, Eun DH, Kim SM, Kim J, Lee WJ

BACKGROUND: Bacteriophages have been introduced as living drugs for infectious diseases; thus, they may provide an alternative to conventional acne therapeutics in patients with non-responsive acne. OBJECTIVE: We investigated the effect...
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Iatrogenic pleural empyema caused by Propionibacterium acnes

Jwa H, Lee J, Seong GM, Kim C

Propionibacterium acnes is one of the commensals living on the human skin and glands, implicated mainly in acnes, but seldom in deep infection. Pleural empyema is rarely complicated with closed...
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Epidermal Growth Factor Attenuated the Expression of Inflammatory Cytokines in Human Epidermal Keratinocyte Exposed to Propionibacterium acnes

Kim JM, Choo JE, Lee HJ, Kim KN, Chang SE

BACKGROUND: While the beneficial effects of topical epidermal growth factor (EGF) on wound healing have been repeatedly reported, there are few reports about the effects of EGF on inflammatory skin...
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Antimicrobial Susceptibility and Characterization of Propionibacterium acnes by Multilocus Sequence Typing and Repetitive-Sequence-Based PCR

Kim S, Song H, Lee WJ, Kim J

Propionibacterium acnes, a gram-positive, anaerobic, and aerotolerant bacterium that is found frequently in the skin as part of the human microbiome causes inflammatory acne, shoulder infection, and the contamination of...
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Efficacy of Red or Infrared Light-Emitting Diodes in a Mouse Model of Propionibacterium acnes-Induced Inflammation

Lee WJ, Lee KC, Kim MJ, Jang YH, Lee SJ, Kim DW

BACKGROUND: Laser/light-based devices may provide an alternative to conventional acne therapeutics in some patients with nonresponsive acne. OBJECTIVE: We investigated the efficacy of red or infrared light-emitting diode (LED) devices in...
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HR-1 Mice: A New Inflammatory Acne Mouse Model

Jang YH, Lee KC, Lee SJ, Kim DW, Lee WJ

BACKGROUND: There is no appropriate in vivo animal model that reflects the inflammatory response of human acne. OBJECTIVE: This study investigated the effect of Propionibacterium acnes on the development of inflammatory...
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Antimicrobial Effects of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Enterococcus faecalis and Propionibacterium acnes

Jo E, Choi MH, Kim HS, Park SN, Lim YK, Kang CK, Kook JK

  • KMID: 1737500
  • Int J Oral Biol.
  • 2014 Jun;39(2):75-79.
The aim of this study was to investigate antimicrobial effect of oleanolic acid (OA), ursolic acid (UA), and sophoraflavanone G against Enterococcus faecalis and Propionibacterium acnes, which are the major...
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Should We Start Treating Chronic Low Back Pain with Antibiotics Rather than with Pain Medications?

Birkenmaier C

For those of us who have read the 2 recently published articles by a Danish - British research group, it might appear that we are observing an impending paradigm shift...
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Analysis and Clinical Correlation of Bacteria Cultured from Patients with Inflammatory Acne

Han JH, Yun SJ, Lee JB, Kim SJ, Lee SC, Won YH

  • KMID: 2088233
  • Korean J Dermatol.
  • 2011 Aug;49(8):676-682.
BACKGROUND: Acne is a common follicular inflammatory dermatosis affecting the pilosebaceous unit. The representative organism isolated from the acne lesion is Propionibacterium acnes, but other aerobic organisms, such as Staphylococcus...
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A Case of Brain Abscess Caused by Propionibacterium acnes 13 Months after Neurosurgery and Confirmed by 16S rRNA Gene Sequencing

Chung S, Kim JS, Seo SW, Ra EK, Joo SI, Kim SY, Park SS, Kim EC

Propionibacterium acnes is a gram-positive anaerobic bacillus and a normal inhabitant of the skin. Although it is often considered a contaminant of blood cultures, it can occasionally cause serious infections,...
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Treatment for Two Cases of Acne Vulgaris with Rubus Coreanus Miquel Extract

Kim DH, Kang SW, Kim BJ

  • KMID: 1458587
  • Korean J Med Mycol.
  • 2010 Sep;15(3):140-145.
Bokbunja (Rubus Coreanus Miquel) is a wild berry to Rosaceae genus of which application areas have been expanded due to many health effects. Bokbunja contains carbohydrates, protein, fats and dietary...
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The Effect of 650 nm Red Light Phototherapy on Acne Vulgaris

Lee J, Oh DH, Yeo KY, Kim JS, Kim SS, Yu HJ

  • KMID: 2247709
  • Korean J Dermatol.
  • 2010 Feb;48(2):101-108.
BACKGROUND: With the emergence of problems with conventional acne vulgaris treatments, the demand for safe and effective treatment has been increasing. Recently, many studies have shown that phototherapy can be...
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The Effect of Blue Light on Propionibacterium acnes and the Expression of Inflammatory Cytokines in HaCaT Cells

Par YD, Lee KS

  • KMID: 2247737
  • Korean J Dermatol.
  • 2009 Nov;47(11):1213-1219.
BACKGROUND: Acne is a multifactorial disease. Particularly, Propionibacterium acne acts on triglycerides and releases cytokines, which trigger inflammatory reactions and alter the infundibular keratinization status. Recently, visible light, especially blue...
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Isolation and Identification of Lactic Acid Bacteria Inhibiting the Proliferation of Propionibacterium acnes and Staphylococcus epidermidis

Kang MS, Oh HJ, Lee HC, Oh JS

Propionibacterium acnes is the most common causative agent of acne. Staphylococcus epidermidis is another major bacterial strain to be found in acne lesions. Two strains of lactic acid bacteria (LAB)...
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Superimposed Propionibacterium Acnes Subdural Empyema in a Patient with Chronic Subdural Hematoma

Kim JH, Lee CH, Hwang SH, Kang DH

The authors present a case of subdural empyema in a macrocephalic patient. A 23-year-old male was admitted due to headache and fever. One month ago, he had mild head injury...
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The Clinical Usefulness of Portable Digital Skin Fluorescence Equipment in Acne Patients

Kim YH, Choi TY, Bae SJ, Kang U, Ro YS

  • KMID: 2248100
  • Korean J Dermatol.
  • 2008 Jul;46(7):889-895.
BACKGROUND: Propionibacterium acnes (P. acnes) is a gram positive anaerobic bacteria which plays a key role in the development of acne. Therefore, culture of P. acnes from the acne lesion...
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A Correlation Study between Sebum Output, Acne Lesion Counts andPore Fluorescence Density in Acne Patients

Hong SP, Han B, Jung B, Bae Y, Choi EH

  • KMID: 2248829
  • Korean J Dermatol.
  • 2007 Sep;45(9):890-897.
BACKGROUND: Porphyrins produced by Propionibacterium acnes exhibit an orange-red fluorescence spot on the pilosebaceous pore under UVA light. Based on this characteristic, the recently developed photographic technique, 'fluorescence photography', warrants...
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Study of the Photoinactivation Effect on Propionibacterium acnes after Light Irradiation with Variable Wavelengths

Cho YJ, Suh DH

  • KMID: 2087193
  • Korean J Dermatol.
  • 2006 Nov;44(11):1332-1338.
BACKGROUND: Phototherapy has been studied as an alternative option for the treatment of acne. Propionibacterium (P.) acnes produces endogenous porphyrins as a by-product of metabolism. Light of particular wavelengths activates...
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Microorganisms Isolated from Acne and Their Antibiotic Susceptibility

Ki HG, Yun SJ, Lee JB, Kim SJ, Lee SC, Won YH

  • KMID: 2302576
  • Korean J Dermatol.
  • 2005 Jul;43(7):871-875.
BACKGROUND: The representative organism isolated from acne lesion is Propionibacterium acnes (P. acnes), but other organisms, such as Staphylococcus epidermidis (S. epidermidis), have also been isolated. These organisms play an...
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A Comparison of the Sebum excretion rate and the Density of Propionibacterium acnes between Adult acne and Adolescent acne

Park HJ, Choi SW, Che KO, Koh JS, Kim HO, Park YJ

  • KMID: 2230356
  • Korean J Dermatol.
  • 2000 Sep;38(9):1199-1204.
BACKGROUND: Acne is principally a disorder of adolescence. However, a number of observational studies have documented a significant degree of acne in adult women. One study found a difference in...
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