- New Oral Agent for Treatment of Anemia in Patient with Chronic Kidney Disease: Prolyl Hydroxylase Inhibitor
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Na K
- KMID: 2438025
- Korean J Med.
- 2019 Feb;94(1):11-16.
- doi: 10.3904/kjm.2019.94.1.11
Hypoxia inducible factor (HIF)-stabilizers are being developed for the renal anemia treatment. This small molecules inhibit prolyl hydroxylase domain (PHD)-containing enzymes, causing HIF activation instead of degradation under the state... -
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- Phospholipase D2 promotes degradation of hypoxia-inducible factor-1alpha independent of lipase activity
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Park MH, Bae SS, Choi KY, Min DS
- KMID: 2359883
- Exp Mol Med.
- 2015 Nov;47(11):e196.
- doi: 10.1038/emm.2015.87
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a key transcriptional mediator that coordinates the expression of various genes involved in tumorigenesis in response to changes in oxygen tension. The stability of HIF-1alpha protein... -
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- Profiling of Proteins Regulated by Venlafaxine during Neural Differentiation of Human Cells
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Doh MS, Han DM, Oh DH, Kim SH, Choi MR, Chai YG
- KMID: 2316393
- Psychiatry Investig.
- 2015 Jan;12(1):81-91.
- doi: 10.4306/pi.2015.12.1.81
OBJECTIVE: Antidepressants are known to positively influence several factors in patients with depressive disorders, resulting in increased neurogenesis and subsequent relief of depressive disorders. To study the effects of venlafaxine... -
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