- The Effect of Repeated Stress on the Modulation of Neuroactive Steroids at the GABAA-Benzodiazepine Receptor Complex in Rats
-
Jang BS, Lee JB, Park HB, Ha JH, Song CJ
- KMID: 2340326
- J Korean Neuropsychiatr Assoc.
- 1999 May;38(3):656-663.
OBJECTIVES: Pregnanolone is a potent positive modulator of the gamma-aminobutyric acid(GABA) response that enhances the binding of [3H]flunitrazepam to the GABA A receptor. Recently, it was reported that chronic... -
- CITED
-
- Close
- SHARE
-
- Close
- Neurosteroid Levels in Patients with Obsessive-Compulsive Disorder
-
Erbay LG, Kartalci S
- KMID: 2391827
- Psychiatry Investig.
- 2015 Oct;12(4):538-544.
- doi: 10.4306/pi.2015.12.4.538
OBJECTIVE: Changes in serum neurosteroid levels have been reported in stress-related disorders such as anxiety and depression, but not in patients with obsessive-compulsive disorder (OCD). We thus investigated such changes... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of Neuroactive Steroids on the GAVA-Benzodiazepine Receptor Complex
-
Lee JB, Park HB, Lee JH, Park KG, Kim CS, Suh HS, Ha JH
- KMID: 1554989
- Korean J Psychopharmacol.
- 1997 Oct;8(2):218-223.
Pregnolone[5beta-pregnan-3alpha-ol-one(5beta3alpha)] and allopregnanolone [(5alpha-pregnan-3alpha-ol-20-one(5alpha3alpha))] are neuroactive steroids that are reduced metabolites of progesterone. It was reported that Neuroactive steroids may have anxiolytic and anticonvulsant action similar to benzodiazepines and barbiturates.... -
- CITED
-
- Close
- SHARE
-
- Close
- Allopregnanolone suppresses mechanical allodynia and internalization of neurokinin-1 receptors at the spinal dorsal horn in a rat postoperative pain model
-
Fujita M, Fukuda T, Sato Y, Takasusuki T, Tanaka M
- KMID: 2400903
- Korean J Pain.
- 2018 Jan;31(1):10-15.
- doi: 10.3344/kjp.2018.31.1.10
BACKGROUND: To identify a new strategy for postoperative pain management, we investigated the analgesic effects of allopregnanolone (Allo) in an incisional pain model, and also assessed its effects on the... -
- CITED
-
- Close
- SHARE
-
- Close
