- Theracurmin Ameliorates Cognitive Dysfunctions in 5XFAD Mice by Improving Synaptic Function and Mitigating Oxidative Stress
-
Kim J, Kim J, Huang Z, Goo N, Bae HJ, Jeong Y, Park HJ, Cai M, Cho K, Jung SY, Bae SK, Ryu JH
- KMID: 2447860
- Biomol Ther.
- 2019 May;27(3):327-335.
- doi: 10.4062/biomolther.2019.046
As the elderly population is increasing, Alzheimer's disease (AD) has become a global issue and many clinical trials have been conducted to evaluate treatments for AD. As these clinical trials... -
- CITED
-
- Close
- SHARE
-
- Close
- Treadmill Exercise Improves Memory Function Depending on Circadian Rhythm Changes in Mice
-
Hwang DS, Kwak HB, Ko IG, Kim SE, Jin JJ, Ji ES, Choi HH, Kwon OY
- KMID: 2362507
- Int Neurourol J.
- 2016 Nov;20(Suppl 2):S141-S149.
- doi: 10.5213/inj.1632738.369
PURPOSE: Exercise enhances memory function by increasing neurogenesis in the hippocampus, and circadian rhythms modulate synaptic plasticity in the hippocampus. The circadian rhythm-dependent effects of treadmill exercise on memory function... -
- CITED
-
- Close
- SHARE
-
- Close
- Dehydroascorbic Acid Attenuates Ischemic Brain Edema and Neurotoxicity in Cerebral Ischemia: An in vivo Study
-
Song J, Park J, Kim JH, Choi JY, Kim JY, Lee KM, Lee JE
- KMID: 2052851
- Exp Neurobiol.
- 2015 Mar;24(1):41-54.
- doi: 10.5607/en.2015.24.1.41
Ischemic stroke results in the diverse phathophysiologies including blood brain barrier (BBB) disruption, brain edema, neuronal cell death, and synaptic loss in brain. Vitamin C has known as the potent... -
- CITED
-
- Close
- SHARE
-
- Close
- Oxygen/Glucose Deprivation and Reperfusion Cause Modifications of Postsynaptic Morphology and Activity in the CA3 Area of Organotypic Hippocampal Slice Cultures
-
Jung YJ, Suh EC, Lee KE
- KMID: 2285451
- Korean J Physiol Pharmacol.
- 2012 Dec;16(6):423-429.
- doi: 10.4196/kjpp.2012.16.6.423
Brain ischemia leads to overstimulation of N-methyl-D-aspartate (NMDA) receptors, referred as excitotoxicity, which mediates neuronal cell death. However, less attention has been paid to changes in synaptic activity and morphology... -
- CITED
-
- Close
- SHARE
-
- Close
- Synaptic Localization of NMDA Receptor and Shank Protein in Hippocampal Neuron in Vitro
-
Baek SY, Kim SS, Yoon S, Kim BS, Kim JB
- KMID: 2092775
- Korean J Anat.
- 2001 Oct;34(5):467-472.
The existence of NMDA receptor and a new organizer protein, Shank, in the postsynaptic density was studied with the cultured hippocampal neurons using by double immunofluorescence method. The hippocampi from... -
- CITED
-
- Close
- SHARE
-
- Close
- Signal Transduction of Ras-like GTPase Activation in the Nervous System
-
Kim DH, Park JK, Bae KW, Park HT
- KMID: 2030735
- Korean J Anat.
- 2001 Feb;34(1):13-21.
Synaptic plasticity has been thought to be a mechanism of synaptic maturation, learning and memory. In this study, the possible involvement of Rac, RhoA, proline-rich tyrosine kinase 2 (PYK2) and... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Transient Cerebral Ischemia on the Expression of N-methyl-D-aspartate receptor subunit 2A, 2B and Neurofilament 200 in the Rat Cerebral Cortex
-
Jung YW, Moon IS, Ko BH
- KMID: 2092656
- Korean J Anat.
- 1998 Aug;31(4):545-555.
Transient cerebral ischemia was induced by bilateral common carotid artery ligation with reperfusion to understand its effect on the expression of NMDA receptor subunits 2A (NR2A), 2B (NR2B), and NF200... -
- CITED
-
- Close
- SHARE
-
- Close
- Morphometric Study of Synapses in the Rat Cerebellar Cortex in Their Early Postnatal Periods
-
Han HJ
- KMID: 2224628
- Korean J Anat.
- 1997 Apr;30(2):183-190.
Early postnatal period is considered as the critical period for formation and maturation of the synapses. And cerebellum has the major role in the development of equilibrium and somatic motor... -
- CITED
-
- Close
- SHARE
-
- Close
