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Porcine epidemic diarrhea virus: an update overview of virus epidemiology, vaccines, and control strategies in South Korea

Jang G, Lee D, Shin S, Lim J, Won H, Eo Y, Kim CH, Lee C

Porcine epidemic diarrhea virus (PEDV) has posed significant financial threats to the domestic pig industry over the last three decades in South Korea. PEDV infection will mostly result in endemic...
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Porcine epidemic diarrhea viruses from Vietnam: isolation, characterization, and neutralizing activity

Do VT, Truong QL, Dao HT, Nguyen TL, Shin M, Shin KR, Hahn TW

Porcine epidemic diarrhea (PED) is characterized by acute enteritis, watery diarrhea, weight loss, dehydration, and death, with high mortality in neonatal piglets. In this study, 3 virus isolates collected in...
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Prevalence and pathologic study of porcine epidemic diarrhea in Jeju

Kim HJ, Yang HS, Kang SC, Kim JH

From April 2014 to September 2015, 153 piglets from 52 farms in Jeju were diagnosed with porcine epidemic diarrhea (PED). The major PED cases were focused on suckling piglets (144...
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Isolation, characterization and neutralizing activity of porcine epidemic diarrhea viruses from Vietnam

Do VT, Truong QL, Dao HT, Nguyen TL, Kim J, Hahn TW

Porcine epidemic diarrhea (PED) is characterized by acute enteritis, watery diarrhea, weight loss, dehydration, and death with high mortality in neonatal piglets. In this study, 3 virus isolates collected in...
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A descriptive study of on-farm biosecurity and management practices during the incursion of porcine epidemic diarrhea into Canadian swine herds, 2014

Perri AM, Poljak Z, Dewey C, Harding JC, O'Sullivan TL

Porcine epidemic diarrhea virus (PEDV) emerged into Canada in January 2014, primarily affecting sow herds. Subsequent epidemiological analyses suggested contaminated feed was the most likely transmission pathway. The primary objective...
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Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin, Vibrio vulnificus FlaB, to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0

Oh SH, Kim Cho YS, Lee HB, Lee SM, Kim WS, Hong L, Cho CS, Choi YJ, Kang SK

Porcine epidemic diarrhea (PED) is a highly contagious enteric swine disease. The large economic impact of PED on the swine industry worldwide has made the development of an effective PED...
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Generation and protective efficacy of a cold-adapted attenuated genotype 2b porcine epidemic diarrhea virus

Won H, Lee DU, Jang G, Noh YH, Lee SC, Choi HW, Yoon IJ, Yoo HS, Lee C

The recent emergence and re-emergence of porcine epidemic diarrhea virus (PEDV) underscore the urgent need for the development of novel, safe, and effective vaccines against the prevailing strain. In this...
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N-terminal Domain of the Spike Protein of Porcine Epidemic Diarrhea Virus as a New Candidate Molecule for a Mucosal Vaccine

Kim SH, Cho BH, Lee KY, Jang YS

Porcine epidemic diarrhea virus (PEDV) is a contagious coronavirus infecting pigs that leads to significant economic losses in the swine industry. Given that PEDV infection occurs in gut epithelial cells...
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Isolation and characterization of a new porcine epidemic diarrhea virus variant that occurred in Korea in 2014

Yang DK, Kim HH, Lee SH, Yoon SS, Park JW, Cho IS

Outbreaks of porcine epidemic diarrhea (PED) have resulted in significant economic losses in the swine industry, and another PED outbreak occurred in 2014 in Korea. Isolating and culturing PED virus...
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Efficacy of inactivated variant porcine epidemic diarrhea virus vaccines in growing pigs

Lee SH, Yang DK, Kim HH, Cho IS

PURPOSE: The first aim of this study was to develop a novel inactivated porcine epidemic diarrhea virus (PEDV) vaccine using the recently isolated Korean PEDV QIAP1401 strain and to evaluate...
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Sequence analysis of the spike gene of Porcine epidemic diarrhea virus isolated from South China during 2011–2015

Zhao X, Li Z, Zeng X, Zhang G, Niu J, Sun B, Ma J

The spike gene of porcine epidemic diarrhea virus (PEDV) was sequenced from 55 South China field strains isolated from pigs with symptoms of diarrhea. The sequences were compared within the...
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Antiviral Activity of Corylus heterophylla Fisch Against Porcine Epidemic Diarrhea Virus Infection

Lee JS, Kwon DH, Song HS, Choi HJ, Yoon K

The porcine epidemic diarrhea virus (PEDV) has recently been shown to cause huge economic losses in the global pork industry. Our results demonstrated that the extract dose-dependently inhibited the replication...
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Genetic diversity of nucleocapsid genes of recent porcine epidemic diarrhea viruses isolated in Korea

Kim K, Park Y, Park B, Truong QL, Park S, Kim J, Hahn TW

Porcine epidemic diarrhea virus (PEDV), a porcine enteropathogenic coronavirus, causes lethal watery diarrhea in piglets, resulting in large economic losses because of high mortality. In November 2013, PEDV reemerged in...
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Recent vaccine technology in industrial animals

Kim H, Lee YK, Kang SC, Han BK, Choi KM

Various new technologies have been applied for developing vaccines against various animal diseases. Virus-like particle (VLP) vaccine technology was used for manufacturing the porcine circovirus type 2 and RNA particle...
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Porcine epidemic diarrhea: a review of current epidemiology and available vaccines

Song D, Moon H, Kang B

Porcine epidemic diarrhea virus (PEDV), an Alphacoronavirus in the family Coronaviridae, causes acute diarrhea, vomiting, dehydration, and high mortality rates in neonatal piglets. PEDV can also cause diarrhea, agalactia, and...
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Reemergence of porcine epidemic diarrhea virus on Jeju Island

Lee S, Ko DH, Kwak SK, Lim CH, Moon SU, Lee DS, Lee C

  • KMID: 1726750
  • Korean J Vet Res.
  • 2014 Sep;54(3):185-188.
Porcine epidemic diarrhea virus (PEDV) strains responsible for recent outbreaks in the United States have been occurring in Mainland Korea since late 2013. Over the past 10 years, PEDV outbreaks...
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Comparison of an enzyme-linked immunosorbent assay with serum neutralization test for serodiagnosis of porcine epidemic diarrhea virus infection

Oh JS, Song DS, Yang JS, Song JY, Moon HJ, Kim TY, Park BK

  • KMID: 1090771
  • J Vet Sci.
  • 2005 Dec;6(4):349-352.
An indirect porcine epidemic diarrhea (PED) virus (PEDV) enzyme-linked immunosorbent assay (ELISA) was compared with the serum neutralization (SN) test by testing 46 samples from experimentally infected sows, 73 samples...
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Effect of soluble porcine aminopeptidase N on antibody production against porcine epidemic diarrhea virus

Oh JS, Song DS, Yang JS, Song JY, Yoo HS, Jang YS, Park BK

  • KMID: 1093631
  • J Vet Sci.
  • 2004 Dec;5(4):353-357.
A few members of coronavirus group I which includes porcine epidemic diarrhea virus (PEDV) use porcine aminopeptidase N (pAPN) as a cellular receptor. Cellular receptors play an important role in...
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