- Shear-Wave Elastography of the Breast: Added Value of a Quality Map in Diagnosis and Prediction of the Biological Characteristics of Breast Cancer
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Zheng X, Huang Y, Liu Y, Wang Y, Mao R, Li F, Cao L, Zhou J
- KMID: 2471634
- Korean J Radiol.
- 2020 Feb;21(2):172-180.
- doi: 10.3348/kjr.2019.0453
OBJECTIVE: To determine the added value of a shear-wave elastography (SWE) quality map (QM) in the diagnosis of breast lesions and in predicting the biological characteristics of invasive breast cancer. MATERIALS... -
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- Heterogeneity of Human γδ T Cells and Their Role in Cancer Immunity
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Lee HW, Chung YS, Kim TJ
- KMID: 2471045
- Immune Netw.
- 2020 Feb;20(1):e5.
- doi: 10.4110/in.2020.20.e5
The γδ T cells are unconventional lymphocytes that function in both innate and adaptive immune responses against various intracellular and infectious stresses. The γδ T cells can be exploited as... -
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- Intrafamilial variability and clinical heterogeneity in a family with PLA2G6-associated neurodegeneration
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Park JK, Youn J, Cho JW
- KMID: 2465835
- Precis Future Med.
- 2019 Sep;3(3):135-138.
- doi: 10.23838/pfm.2019.00086
Phospholipase A2 group VI (PLA2G6)-associated neurodegeneration (PLAN) is an autosomal recessive neurodegenerative disease with a wide clinical spectrum; however, the genotype-phenotype correlation is unknown. Here, we report different phenotypes in... -
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- Monitoring Glutathione Dynamics and Heterogeneity in Living Stem Cells
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Jeong EM, Shin JW, Lim J, Kim JH, Kang H, Yin Y, Kim HM, Kim Y, Kim SG, Kang HS, Shin DM, Choi K, Kim IG
- KMID: 2465906
- Int J Stem Cells.
- 2019 Jul;12(2):367-379.
- doi: 10.15283/ijsc18151
Glutathione (GSH) is a major antioxidant in cells, and plays vital roles in the cellular defense against oxidants and in the regulation of redox signals. In a previous report, we... -
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- Effects of TGF-β1 Overexpression on Biological Characteristics of Human Dental Pulp-derived Mesenchymal Stromal Cells
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Salkın H, Gönen ZB, Ergen E, Bahar D, Çetin M
- KMID: 2447235
- Int J Stem Cells.
- 2019 Mar;12(1):170-182.
- doi: 10.15283/ijsc18051
OBJECTIVE: The aim of our study was to investigate the effect of Transforming growth factor beta-1 (TGF-β1) gene therapy on the surface markers, multilineage differentiation, viability, apoptosis, cell cycle, DNA... -
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- Biological characteristics of osteoporosis drugs: the effect of osteoblast–osteoclast coupling
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Kim SJ, Moon SJ, Seo JT
- KMID: 2446934
- Int J Oral Biol.
- 2019 Mar;44(1):1-7.
- doi: 10.11620/IJOB.2019.44.1.1
Osteoporosis is a common disease characterized by bone mass reduction, leading to an increased risk of bone fracture, and it is caused by an imbalance of osteoblastic bone formation and... -
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- Assessment of the Clinical Heterogeneity of Kawasaki Disease Using Genetic Variants of BLK and FCGR2A
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Sim BK, Park H, Kim JJ, Yun SW, Yu JJ, Yoon KL, Lee KY, Kil HR, Kim GB, Han MK, Song MS, Lee HD, Ha KS, Sohn S, Hong YM, Jang GY, Lee JK, on behalf of the Korean Kawasaki Disease Genetics Consortium
- KMID: 2430753
- Korean Circ J.
- 2019 Jan;49(1):99-108.
- doi: 10.4070/kcj.2018.0224
BACKGROUND AND OBJECTIVES: Patients with Kawasaki disease (KD) are clinically heterogeneous because its diagnosis is based solely on clinical observation and there are no definitive biomarkers. We dissected the clinical... -
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- Cerebral Microbleeds and the Heterogeneity of Parkinson's Disease
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Yang HJ
- KMID: 2432128
- J Korean Med Sci.
- 2018 Nov;33(46):e293.
- doi: 10.3346/jkms.2018.33.e293
No abstract available. -
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- Genetic Alterations among Korean Melanoma Patients Showing Tumor Heterogeneity: A Comparison between Primary Tumors and Corresponding Metastatic Lesions
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Lee SH, Kim JE, Jang HS, Park KH, Oh BH, Shin SJ, Chung KY, Roh MR, Rha SY
- KMID: 2424809
- Cancer Res Treat.
- 2018 Oct;50(4):1378-1387.
- doi: 10.4143/crt.2017.535
PURPOSE: Melanoma is a highly heterogeneous neoplasm, composed of subpopulations of tumor cells with distinct molecular and biological phenotypes and genotypes. In this study, to determine the genetic heterogeneity between... -
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- The Author Reply: Genotypic and Phenotypic Heterogeneity of LGMD1D due to DNAJB6 Mutations
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Kim K, Choi YC
- KMID: 2419738
- Yonsei Med J.
- 2018 Oct;59(8):1010-1011.
- doi: 10.3349/ymj.2018.59.8.1010
No abstract available. -
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- Genotypic and Phenotypic Heterogeneity of LGMD1D due to DNAJB6 Mutations
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Finsterer
- KMID: 2419737
- Yonsei Med J.
- 2018 Oct;59(8):1008-1009.
- doi: 10.3349/ymj.2018.59.8.1008
No abstract available. -
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- Clinical Heterogeneity of Anti-GM2-Ganglioside-Antibody Syndrome
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Kim JK, Kim YH, Yoon BA, Cho JY, Oh SY, Shin HY, Kim JS, Park KH, Kim SY, Suh BC, Seok HY, Yoo JH, Bae JS
- KMID: 2415059
- J Clin Neurol.
- 2018 Jul;14(3):401-406.
- doi: 10.3988/jcn.2018.14.3.401
BACKGROUND AND PURPOSE: Antiganglioside antibodies are known to play a pathogenic role in Guillain-Barré syndrome (GBS). Either an immunoglobulin (Ig)G- or IgM-type anti-GM2 antibody is detected in rare cases in... -
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- Heterogeneity Does Matter for Tumor Characterization
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Lee WW
- KMID: 2414806
- Nucl Med Mol Imaging.
- 2018 Jun;52(3):167-167.
- doi: 10.1007/s13139-018-0525-x
No abstract available. -
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- Histopathologic heterogeneity of acute respiratory distress syndrome revealed by surgical lung biopsy and its clinical implications
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Park J, Lee YJ, Lee J, Park SS, Cho YJ, Lee SM, Kim YW, Han SK, Yoo CG
- KMID: 2411581
- Korean J Intern Med.
- 2018 May;33(3):532-540.
- doi: 10.3904/kjim.2016.346
BACKGROUND/AIMS: Diffuse alveolar damage (DAD) is the histopathologic hallmark of acute respiratory distress syndrome (ARDS). However, there are several non-DAD conditions mimicking ARDS. The purpose of this study was to... -
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- The significance of intertumor and intratumor heterogeneity in liver cancer
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Liu J, Dang H, Wang XW
- KMID: 2438346
- Exp Mol Med.
- 2018 Jan;50(1):e416.
- doi: 10.1038/emm.2017.165
Genomic analyses of primary liver cancer samples reveal a complex mutational landscape with vast intertumor and intratumor heterogeneity. Different primary liver tumors and subclones within each tumor display striking molecular... -
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- Deciphering cellular and molecular causes of the tumor functional heterogeneity of liver cancer
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Nam SW
- KMID: 2438345
- Exp Mol Med.
- 2018 Jan;50(1):e415.
- doi: 10.1038/emm.2017.188
No abstract available. -
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- A New Perspective on the Heterogeneity of Cancer Glycolysis
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Neugent ML, Goodwin J, Sankaranarayanan I, Yetkin CE, Hsieh MH, Kim JW
- KMID: 2400810
- Biomol Ther.
- 2018 Jan;26(1):10-18.
- doi: 10.4062/biomolther.2017.210
Tumors are dynamic metabolic systems which highly augmented metabolic fluxes and nutrient needs to support cellular proliferation and physiological function. For many years, a central hallmark of tumor metabolism has... -
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- Current Understanding in Neutrophil Differentiation and Heterogeneity
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Hong CW
- KMID: 2400635
- Immune Netw.
- 2017 Oct;17(5):298-306.
- doi: 10.4110/in.2017.17.5.298
Neutrophils are professional phagocytes that conduct effectors functions in the innate immune systems. They are differentiated in the bone marrow (BM) and terminally differentiated neutrophils are then released into systemic... -
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- Heterogeneity in Trajectories of Body Mass Index and Their Associations with Mortality in Old Age: A Literature Review
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Murayama H, Shaw BA
- KMID: 2392943
- J Obes Metab Syndr.
- 2017 Sep;26(3):181-187.
- doi: 10.7570/jomes.2017.26.3.181
This article reviewed studies to investigate the association between trajectories of body mass index (BMI) and mortality among older adults. Investigators conducted a systematic search of published peer-reviewed literature in... -
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- HER2 Status and Its Heterogeneity in Gastric Carcinoma of Vietnamese Patient
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Phan DA, Nguyen VT, Hua TN, Ngo QD, Doan TP, Nguyen ST, Thai AT, Nguyen VT
- KMID: 2392580
- J Pathol Transl Med.
- 2017 Jul;51(4):396-402.
- doi: 10.4132/jptm.2017.04.24
BACKGROUND: Human epidermal growth factor receptor 2 (HER2) is related to the pathogenesis and poor outcome of numerous types of carcinomas, including gastric carcinoma. Gastric cancer patients with HER2 positivity... -
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