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Alteration of cellular events in tooth development by chemical chaperon, Tauroursodeoxycholic acid treatment

Lee ES, Aryal YP, Kim TY, Pokharel E, Kim H, Sung S, Sohn WJ, Lee Y, An CH, Kim JY

Several factors, including genetic and environmental insults, impede protein folding and secretion in the endoplasmic reticulum (ER). Accumulation of unfolded or mis-folded protein in the ER manifests as ER stress....
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