- Eradication Therapy for Helicobacter pylori with Diagnostic Test for Clarithromycin Resistance
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Kim YJ, Chung WC
- KMID: 2469313
- Korean J Helicobacter Up Gastrointest Res.
- 2019 Dec;19(4):225-230.
- doi: 10.7704/kjhugr.2019.0019
Addressing the increasing antibiotic resistance, including clarithromycin resistance, which affects Helicobacter pylori (H. pylori) eradication therapy, is a challenge for clinicians. Antibiotic resistance is the main reason for H. pylori... -
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- Clarithromycin resistance and female gender affect Helicobacter pylori eradication failure in chronic gastritis
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Chang YW, Ko WJ, Oh CH, Park YM, Oh SJ, Moon JR, Cho JH, Kim JW, Jang JY
- KMID: 2457025
- Korean J Intern Med.
- 2019 Sep;34(5):1022-1029.
- doi: 10.3904/kjim.2018.054
BACKGROUND/AIMS: The eradication rate of the first-line triple therapy (a proton pump inhibitor, clarithromycin, and amoxicillin) for Helicobacter pylori infection has gradually decreased in Korea. We evaluated whether clinical parameters,... -
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- Role of Androgen Receptor in Prostate Cancer: A Review
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Fujita K, Nonomura N
- KMID: 2455406
- World J Mens Health.
- 2019 Sep;37(3):288-295.
- doi: 10.5534/wjmh.180040
Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding domain, hinge region, and ligand-binding domain. AR plays... -
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- De novo mutations in COL4A5 identified by whole exome sequencing in 2 girls with Alport syndrome in Korea
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Han KH, Park JE, Ki CS
- KMID: 2451970
- Korean J Pediatr.
- 2019 May;62(5):193-197.
- doi: 10.3345/kjp.2018.06772
Alport syndrome (ATS) is an inherited glomerular disease caused by mutations in one of the type IV collagen novel chains (α3, α4, and α5). ATS is characterized by persistent microscopic... -
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- Molecular Testing of Thyroid Indeterminate Nodules for Clinical Management Decision
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Kim HK, Soh EY
- KMID: 2449060
- Int J Thyroidol.
- 2019 May;12(1):9-14.
- doi: 10.11106/ijt.2019.12.1.9
Thyroid nodules are the most common endocrine tumor. Ultrasonography and fine-needle aspiration (FNA) are currently accurate diagnostic tools for evaluating thyroid nodules. However, 10–30% of FNA specimens are cytologically indeterminate.... -
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- Encapsulated Papillary Thyroid Tumor with Delicate Nuclear Changes and a KRAS Mutation as a Possible Novel Subtype of Borderline Tumor
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Ohba K, Mitsutake , Matsuse M, Rogounovitch T, Nishino N, Oki Y, Goto Y, Kakudo K
- KMID: 2465454
- J Pathol Transl Med.
- 2019 Mar;53(2):136-141.
- doi: 10.4132/jptm.2018.12.07
Although papillary thyroid carcinoma (PTC)–type nuclear changes are the most reliable morphological feature in the diagnosis of PTC, the nuclear assessment used to identify these changes is highly subjective. Here,... -
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- Landscape of Actionable Genetic Alterations Profiled from 1,071 Tumor Samples in Korean Cancer Patients
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Lee SH, Lee B, Shim JH, Lee KW, Yun JW, Kim SY, Kim TY, Kim YH, Ko YH, Chung HC, Yu CS, Lee J, Rha SY, Kim TW, Jung KH, Im SA, Moon HG, Cho S, Kang JH, Kim J, Kim SK, Ryu HS, Ha SY, Kim JI, Chung YJ, Kim C, Kim HL, Park WY, Noh DY, Park K
- KMID: 2437614
- Cancer Res Treat.
- 2019 Jan;51(1):211-222.
- doi: 10.4143/crt.2018.132
PURPOSE: With the emergence of next-generation sequencing (NGS) technology, profiling a wide range of genomic alterations has become a possibility resulting in improved implementation of targeted cancer therapy. In Asian... -
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- Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen
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Kulwanich , Thanyaratsrisakul S, Jirapongsananuruk O, Hales BJ, Thomas WR, Piboonpocanun S
- KMID: 2426791
- Allergy Asthma Immunol Res.
- 2019 Jan;11(1):129-142.
- doi: 10.4168/aair.2019.11.1.129
PURPOSE: Hypoallergenic recombinant Der p 2 has been produced by various genetic manipulations, but mutation of a naturally polymorphic amino acid residue known to affect IgE binding has not been... -
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- Failure of Ciprofloxacin Therapy in the Treatment of Community-Acquired Acute Pyelonephritis caused by In-Vitro Susceptible Escherichia coli Strain Producing CTX-Type Extended-Spectrum β-Lactamase
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Seok H, Cha MK, Kang CI, Cho SY, Kim SH, Ha YE, Chung DR, Peck KR, Song JH
- KMID: 2429940
- Infect Chemother.
- 2018 Dec;50(4):357-361.
- doi: 10.3947/ic.2018.50.4.357
While carbapenems are the drug of choice to treat extended-spectrum-β-lactamase (ESBL)-producing strains, some alternative carbapenem-sparing regimens are suggested for antibiotic stewardship. We experienced a case of ciprofloxacin treatment failure for... -
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- Peptide Nucleic Acid Probe-Based Analysis as a New Detection Method for Clarithromycin Resistance in Helicobacter pylori
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Jung DH, Kim JH, Jeong SJ, Park SY, Kang IM, Lee KH, Song YG
- KMID: 2427454
- Gut Liver.
- 2018 Nov;12(6):641-647.
- doi: 10.5009/gnl18111
BACKGROUND/AIMS: Helicobacter pylori eradication rates are decreasing because of increases in clarithromycin resistance. Thus, finding an easy and accurate method of detecting clarithromycin resistance is important. METHODS: We evaluated 70 H.... -
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- Microcystic Stromal Tumor of Testicle: First Case Report and Literature Review
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Zhu P, Duan Y, Ao Q, Wang G
- KMID: 2424815
- Cancer Res Treat.
- 2018 Oct;50(4):1452-1457.
- doi: 10.4143/crt.2017.414
Microcystic stromal tumor (MCST) is a rare subtype of sex cord-stromal neoplasm. Tumors from all 31 previously reported cases were located in the ovary. Herein, we present a unique case... -
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- The Association of Acquired T790M Mutation with Clinical Characteristics after Resistance to First-Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma
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Huang YH, Hsu KH, Tseng JS, Chen KC, Hsu CH, Su KY, Chen JJ, Chen HW, Yu SL, Yang TY, Chang GC
- KMID: 2424801
- Cancer Res Treat.
- 2018 Oct;50(4):1294-1303.
- doi: 10.4143/crt.2017.512
PURPOSE: The main objective of this study was to investigate the relationship among the clinical characteristics and the frequency of T790M mutation in advanced epidermal growth factor receptor (EGFR)–mutant lung... -
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- Huge Steatocystoma Multiplex with New Point Mutation in the Exon 1 of KRT 17 Gene
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Kim JY, Park JH, Sohng C, Jang YH, Lee SJ, Lee WJ
- KMID: 2419764
- Ann Dermatol.
- 2018 Oct;30(5):633-635.
- doi: 10.5021/ad.2018.30.5.633
No abstract available. -
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- A family with NKX2.5 gene mutations presenting as familial atrial septal defect and atrioventricular block: A case report
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Choi YY, Woo MH, Kim GB, Song MK, Lee SY, Bae EJ, Choi M, Kim YS
- KMID: 2435968
- J Genet Med.
- 2018 Jun;15(1):20-23.
- doi: 10.5734/JGM.2018.15.1.20
Point mutations in the human cardiac homeobox gene NKX2.5 are associated with familial atrial septal defect (ASD), atrioventricular (AV) conduction disturbance, as well as sudden cardiac death. To date, more... -
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- Type 1 Lissencephaly with Ocular Abnormality and Cranial Nerve Palsies
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Seo IA, Cho SY, Choi SM
- KMID: 2409127
- Perinatology.
- 2017 Dec;28(4):171-176.
- doi: 10.14734/PN.2017.28.4.171
Lissencephaly is a cerebral cortical malformation characterized by partial to total loss of gyri and sulci of brain leading to mental retardation and epilepsy. It is caused by failure of... -
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- Mechanisms of quinolone resistance in Escherichia coli isolated from companion animals, pet-owners, and non-pet-owners
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Chung YS, Hu YS, Shin S, Lim SK, Yang SJ, Park YH, Park KT
- KMID: 2398503
- J Vet Sci.
- 2017 Dec;18(4):449-456.
- doi: 10.4142/jvs.2017.18.4.449
The present study investigated the prevalence and mechanisms of fluoroquinolone (FQ)/quinolone (Q) resistance in Escherichia (E.) coli isolates from companion animals, pet-owners, and non-pet-owners. A total of 63 E. coli... -
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- A Pilot Study of Helicobacter pylori Eradication Using a Polymerase Chain Reaction-based Test for Clarithromycin Resistance
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Jung YD, Kim YJ, Chung WC
- KMID: 2397495
- Korean J Helicobacter Up Gastrointest Res.
- 2017 Dec;17(4):200-207.
- doi: 10.7704/kjhugr.2017.17.4.200
BACKGROUND/AIMS: Clarithromycin resistance is one of the main predictors of eradication treatment failures in Helicobacter pylori infections. The aim of this study was to investigate the ideal eradication rate of... -
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- Late-onset MELAS with Chronic Kidney Disease
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Choo IY, Lee EJ, Min YG, Kwon HM
- KMID: 2405987
- J Korean Neurol Assoc.
- 2017 Nov;35(4):237-239.
- doi: 10.17340/jkna.2017.4.12
Mitochondrial encephalomyopathy with lactic acid and stroke-like episodes (MELAS) is a multisystem mitochondrial disorder that typically presents in childhood. We report a case of MELAS syndrome diagnosed in a 45-year-old... -
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- MPTP-induced vulnerability of dopamine neurons in A53T α-synuclein overexpressed mice with the potential involvement of DJ-1 downregulation
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Lee S, Oh ST, Jeong HJ, Pak SC, Park HJ, Kim J, Cho HS, Jeon S
- KMID: 2395257
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):625-632.
- doi: 10.4196/kjpp.2017.21.6.625
Familial Parkinson's disease (PD) has been linked to point mutations and duplication of the α-synuclein (α-syn) gene. Mutant α-syn expression increases the vulnerability of neurons to exogenous insults. In this... -
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- Macrolide Resistance and Its Impacts on M. Pneumoniae Pneumonia in Children: Comparison of Two Recent Epidemics in Korea
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Kim JH, Kim JY, Yoo CH, Seo WH, Yoo Y, Song DJ, Choung JT
- KMID: 2378197
- Allergy Asthma Immunol Res.
- 2017 Jul;9(4):340-346.
- doi: 10.4168/aair.2017.9.4.340
PURPOSE: The aim of this study was to investigate the change in macrolide resistance rate in pediatric Mycoplasma pneumoniae pneumonia and to evaluate the influence of macrolide-resistant M. pneumoniae (MRMP)... -
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