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Evaluation and management of platelet transfusion refractoriness

Youk HJ, Hwang SH, Oh HB, Ko DH

Platelet transfusion refractoriness (PTR), in which platelet counts do not increase after transfusion, occurs in many patients receiving platelet transfusions. PTR is a clinical condition that can harm patients. The...
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The incidence of postoperative hemorrhage after tooth extraction in patients with thrombocytopenia

Kang SH, Kang MJ

Objectives: The risk of bleeding after tooth extraction in thrombocytopenia patients remains unclear. Therefore, the present study aimed to assess the risk of bleeding after tooth extraction in patients with...
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Platelet Serotonin Concentration Is Associated with Illness Duration in Schizophrenia and Chronological Age in Depression

Peitl V, Getaldić-Švarc B, Karlović D

Objective Impaired serotonergic neurotransmission has been implicated in the pathogenesis of depression and schizophrenia. Blood platelets have been used for years as a peripheral model of neuronal serotonin dynamics. The...
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The Platelet-to-Lymphocyte Ratio as an Inflammatory Marker in Rheumatic Diseases

Gasparyan , Ayvazyan L, Mukanova U, Yessirkepov M, Kitas GD

The platelet-to-lymphocyte ratio (PLR) has emerged as an informative marker revealing shifts in platelet and lymphocyte counts due to acute inflammatory and prothrombotic states. PLR has been extensively examined in...
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An Elevated Platelet Count Increases the Risk of Relapse in Ulcerative Colitis Patients with Mucosal Healing

Nakarai A, Kato J, Hiraoka S, Takashima , Inokuchi T, Takahara M, Sugihara Y, Harada K, Okada H

BACKGROUND/AIMS: Although mucosal healing (MH) has been considered a treatment goal for patients with ulcerative colitis (UC), the risk factors predictive of relapse in patients who achieve MH are unknown....
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The Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Are Prognostic Factors in Patients with Locally Advanced Pancreatic Cancer Treated with Chemoradiotherapy

Lee BM, Chung SY, Chang JS, Lee KJ, Seong J

BACKGROUND/AIMS: We investigated whether inflammatory markers such as neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) independently and in combination would be significant prognostic factors for survival in patients with locally...
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Benefits of Thromboelastography and Thrombin Generation Assay for Bleeding Prediction in Patients With Thrombocytopenia or Hematologic Malignancies

Kim SY, Gu JY, Yoo HJ, Kim JE, Jang S, Choe S, Koh Y, Kim I, Kim HK

BACKGROUND: Thromboelastography (TEG) provides comprehensive information on the whole blood clot formation phases, whereas thrombin generation assay (TGA) reveals the endogenous thrombin levels in plasma. We investigated the potential significance...
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Myeloma prognostic index at diagnosis might be a prognostic marker in patients newly diagnosed with multiple myeloma

Kim DS, Yu ES, Kang KW, Lee SR, Park Y, Sung HJ, Choi CW, Kim BS

BACKGROUND/AIMS: The aims of this study were to identify the value of inflammatory markers as pretreatment prognostic factors for patients with multiple myeloma (MM) and to estimate the value of...
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The Effects of Helicobacter pylori Eradication Therapy for Chronic Idiopathic Thrombocytopenic Purpura

Hwang JJ, Lee DH, Yoon H, Shin CM, Park YS, Kim N

BACKGROUND/AIMS: The aim of this study was to evaluate the ability of Helicobacter pylori eradication treatment to increase platelet counts in Korean patients with chronic idiopathic thrombocytopenic purpura (ITP). METHODS: A...
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Evaluation of Platelet count by the CELL-DYN Sapphire CD61 Immunoplatelet Method in Patients with Hematologic Diseases Receiving Chemotherapy

Kim BR, Choi JL, Kim JE, Woo KS, Kim KH, Kim JM, Kim SH, Han JY

BACKGROUND: The automated hematologic analyzer has increased the precision and accuracy for platelet counting. However, spurious elevations of automated platelet counts occur occasionally in patients receiving chemotherapy or radiotherapy for...
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Predictive role of hematologic parameters in testicular torsion

Gunes M, Umul M, Altok M, Akyuz M, Isoglu CS, Uruc F, Aras B, Akbas A, Bas E

PURPOSE: To evaluate the predictive role of the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), mean platelet volume (MPV), and platelet count (PLT) in the diagnosis of...
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The Cheapest and Easiest Way to Make Platelet-rich Plasma Preparation

Choi HM, Kim SH, Kim CK, Choi HG, Shin DH, Uhm KI, Jo D

BACKGROUND: Platelet-rich plasma (PRP) has been advocated as a way to introduce increased concentrations of growth factors and other bioactive molecules to injured tissues in an attempt to optimize the...
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Genome-Wide Association Study Identifies Candidate Loci Associated with Platelet Count in Koreans

Oh JH, Kim YK, Moon S, Kim YJ, Kim BJ

Platelets are derived from the fragments that are formed from the cytoplasm of bone marrow megakaryocytes-small irregularly shaped anuclear cells. Platelets respond to vascular damage, contracts blood vessels, and attaches...
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Platelet-Rich Plasma: Quantitative Assessment of Growth Factor Levels and Comparative Analysis of Activated and Inactivated Groups

Lee JW, Kwon OH, Kim TK, Cho YK, Choi KY, Chung HY, Cho BC, Yang JD, Shin JH

BACKGROUND: Platelet-rich plasma (PRP) has more concentrated platelets than normal plasma (approximately 150-400x10(3) cell/dL). Platelets excrete several growth factors and cytokines that are associated with the healing and regeneration process....
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Hepatic Rupture Caused by Hemolysis, Elevated Liver Enzyme, and Low Platelet Count Syndrome: A Case Report with Computed Tomographic and Conventional Angiographic Findings

Lee CB, Ahn JH, Choi SJ, Lee JH, Park MS, Jung SM, Ryu DS

  • KMID: 2322597
  • J Korean Soc Radiol.
  • 2013 May;68(5):407-410.
The authors recently obtained successful clinical outcome after embolization of the hepatic artery and right inferior phrenic artery in a pregnant patient with hemolysis, elevated liver enzyme, and low platelet...
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Usefulness of Thrombocytopenia and Changes in Platelet Counts as Prognostic Markers in Pediatric Intensive Care Units

Kim YH, Park HB, Kim MJ, Kim HS, Lee HS, Han YK, Kim KW, Sohn MH, Kim KE

BACKGROUND: Thrombocytopenia has been shown to be a useful predictor of mortality in adult intensive care units (ICUs). The aim of this study is to assess whether the level of...
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Diagnostic Usefulness of Basic Hematologic Tests for the Detection of Bacteremia in Febrile Patients with Neutrophilia

Cho YU, Kang JY, Chae JD, Son BK

  • KMID: 2312206
  • Lab Med Online.
  • 2012 Oct;2(4):197-203.
BACKGROUND: Alterations in blood cell count are well recognized features of bacteremia. The study objective was to determine the hematologic changes predictive of bacteremia. METHODS: We retrospectively studied febrile adult patients...
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Hematologic Characteristics of Intrauterine Growth Restricted Small for Gestational Age Infants

Kim SJ, Cho IH, Cho YS, Youn YA, Lee JY, Lee HS, Lee JH, Sung IK, Kim SY

PURPOSE: Intrauterine growth retardation (IUGR) is the term used to designate a fetus that has not reached its growth potential. However it is difficult to make a distinction between infants...
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A Serial Study of Hematologic Change in Burned Patients

Kim HS, Kwon HW, Yang HT, Chun W, Shin KS, Lee YK, Park JY, Cho HC, Lee KM

  • KMID: 1848727
  • J Lab Med Qual Assur.
  • 2011 Jun;33(1):9-16.
BACKGROUND: Hematologic changes in burned patients show unique patterns with time after burn injury. In this study, we analyzed the changes of leukocyte count, hemoglobin concentration, and platelet count according...
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Effects of Helicobacter pylori eradication in patients with immune thrombocytopenic purpura

Tag HS, Lee HS, Jung SH, Kim BK, Kim SB, Lee A, Lee JS, Shin SH, Kim YS

BACKGROUND: The relationship between Helicobacter pylori (H. pylori) infection and chronic idiopathic thrombocytopenic purpura (ITP) has been confirmed; however, no clear evidence for the effectiveness of H. pylori eradication on...
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