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Plasmodium vivax dhfr Mutations among Isolates from Malarious Areas of Iran

Zaman J, Shahbazi A, Asgharzadeh M

The use of sulfadoxine and pyrimethamine (SP) for treatment of vivax malaria is uncommon in most malarious areas, but Plasmodium vivax isolates are exposed to SP because of mixed infections...
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Aspartic proteases of Plasmodium vivax are highly conserved in wild isolates

Na BK, Lee EG, Lee HW, Cho SH, Bae YA, Kong Y, Lee JK, Kim TS

The plasmepsins are the aspartic proteases of malaria parasites. Treatment of aspartic protease inhibitor inhibits hemoglobin hydrolysis and blocks the parasite development in vitro suggesting that these proteases might be...
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