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Porokeratosis of Mibelli with Amyloid Deposits in Dermis

Kim JY, Choi JW, Paik SH, Suh DH, Cho KH

  • KMID: 2247314
  • Korean J Dermatol.
  • 2012 Sep;50(9):822-825.
Porokeratosis of Mibelli, a chronic heritable disorder of the skin, presents with characteristic histopathological features including cornoid lamella as a result of faulty keratinization. Amyloid deposits are characterized by the...
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Secondary Localized Cutaneous Amyloidosis in Seborrheic Keratosis

Lee JH, Ahn HT, Lee DY, Cho KH

  • KMID: 1595098
  • Korean J Dermatol.
  • 2001 Mar;39(3):370-372.
We examined the amyloid deposits in seborrheic keratosis by using Dylon stain. Histochemically identified amyloid deposits in seborrheic keratosis were studied with monoclonal cytokeratin antibodies. Amyloid deposits were detected in...
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A Case of Disseminated Superficial Porokeratosis with Dermal Amyloid Deposition

Kim DY, Lee KY, Jang JY, Bang D

  • KMID: 2248941
  • Korean J Dermatol.
  • 2006 Aug;44(8):1018-1020.
Secondary localized cutaneous amyloidosis appears in association with a variety of inflammatory skin diseases and skin tumors. The presence of dermal amyloid deposits in lesions of porokeratosis has rarely been...
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A Case of Cerebral Amyloid Angiopathy-related Intracerebral Hemorrhage

Lee HS, Park IS, Whang SH, Paek SH, Kim ES, Jung JM, Han JW

  • KMID: 2019042
  • J Korean Neurosurg Soc.
  • 1998 Mar;27(3):387-391.
Cerebral amyloid angiopathy(CAA) is a nonspecific disease entity that has been associated with a number of neuropathologic conditions, the most prominent being dementia and cerebral hemorrhage. It occurs more commonly...
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Amyloid Deposit in Malignant Cutaneous Epithelial Tumors

Cho KH, Kim KH, Chang SH, Ham EK

  • KMID: 1920693
  • Korean J Dermatol.
  • 1990 Dec;28(6):715-721.
We examined the amyloid deposit in various malignant cutaneous epithelial tumors by using Dylon stain. Histochemically identifiable amyloid deposits associated with basal cell epitheliomas(BCEs), squamous cell carcinomas(SCCs) and Bowens diseases...
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Prospect of Geriatric Psychiatric Research: Research on Alzheimer's Disease

Kim SH, Lee HJ

  • KMID: 2340752
  • J Korean Neuropsychiatr Assoc.
  • 2002 Sep;41(5):767-777.
Alzheimer's disease(AD) is a progressive dementia characterized by global cognitive decline and is defined pathologically by amyloid plaques and neurofibrillary tangles. In the past 10 years, important progress has been...
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A Case of Macroglossia due to Amyloidosis Associated with Multiple Myeloma

Kim RY, Lee JJ, Lee DH, Lee JK

Amyloidosis is a condition of abnormal deposition of extracellular insoluble fibrillar proteins, termed amyloid, in tissue and organs throughout the body. Systemic amyloidosis, consisting of light amyloid protein (AL protein),...
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Drug Development for Alzheimer's Disease: Recent Progress

Ji W, Ha I

Alzheimer's disease, the most common cause of dementia, is characterized by two major pathological hallmarks: amyloid plaques and neurofibrillary tangles. Based on these two indicators, an amyloid cascade hypothesis was...
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Two Cases of Lichen Amyloidosis Associated With Atopic Dermatitis

Lee JS, Myung JW, Ha SJ, Kim SY

  • KMID: 2303133
  • Korean J Dermatol.
  • 2002 Aug;40(8):994-996.
Lichen amyloidosis is a chronic intensely pruritic skin disorder characterized histologi-cally by the deposition of amyloid in the papillary dermis. Lichen amyloidosis has been reported in association with several pruritic...
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Amyloid Goiter with Parathyroid Involvement

Yun MY, Cho YU, Choi SJ, Choi SK, Hur YS, Lee KY, Kim SJ, Ahn SI, Hong KC, Shin SH, Kim KR, Woo ZH

  • KMID: 2210904
  • J Korean Surg Soc.
  • 2006 Nov;71(5):361-364.
The amyloid deposition observed in secondary amyloidosis frequently involves the thyroid gland, but rarely is a goiter responsible for this. We report here the pathologic findings of a case of...
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Macular Amyloidosis Presented as Depressed Patches on the Face

Song HJ, Hong WK, Lee HS, Choi GS, Shin JH

  • KMID: 2302124
  • Korean J Dermatol.
  • 2008 Feb;46(2):285-288.
We report a 58-year-old woman with an unusual clinical presentation of macular amyloidosis who had erythematous depressed patches without rippled pattern. The lesion was localized involving only the face: both...
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Primary Rectal Amyloidosis in a Patient with Human Immunodeficiency Virus

Lee SH, Kim TO, Bae JH, Park JH, Jeon YK, Kim TK, Song GA

  • KMID: 1744242
  • Gut Liver.
  • 2009 Mar;3(1):57-59.
Amyloidosis can involve a single organ or multiple organs. The gastrointestinal tract is a common site of amyloid deposition. We report a rare case of solitary rectal amyloidosis in a...
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Clinical and Pathological Characteristics of Frontotemporal Lobar Degeneration(FTLD) and Molecular Genetics of Tau Protein

Woo SI

  • KMID: 2202778
  • J Korean Soc Biol Psychiatry.
  • 2003 Nov;10(2):97-106.
Criticisms about amyloid cascade hypothesis of Alzheimer's disease(AD) are based on the findings, first, that the degree of dementia does not correlate with the number of plaques, and second, that...
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A Case of Amyloid Goiter Masquerading as Graves' Disease

Kim HB, Lee SH, Ko KB, Cho JH

Amyloidosis is an abnormal extracellular deposit of amyloid in various organs of the body. Amyloid goiter, defined by a clinically detectable thyroid enlargement due to amyloid deposition, is a rare...
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A Newer Therapeutic Strategies For Alzheimer's Disease

Han SH

  • KMID: 2185998
  • J Korean Neurol Assoc.
  • 2001 Nov;19(6):559-565.
Alzheimer's disease (AD) is characterized pathologically by cholinergic deficits, extracelluar amyloid deposit, intra-neuronal neurofibrillary tangles, gliosis and neuronal and synaptic loss. The primary therapeutic approach has been cholinergic augumentation by...
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Immunohistochemical Staining of Amyloid Deposit with Monoclonal Anti - keratin Antibodies in Primary Localized Cutaneous Amyloidosis

Cho KH, Chang SH, Kim JA, Lee YS, Ham EK

  • KMID: 2231255
  • Korean J Dermatol.
  • 1990 Jun;28(3):308-314.
Nine cases of primary localized cutaneous amyloidosis were studied by immunoperoxidase technique (ABC method) employing anti-keratin antibodies. All specimens were examined using consecutive paraffin sections to confirm the correspondence between...
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Cerebral Amyloid Angiopathy: A Systematic Review

Biffi A, Greenberg

Cerebral amyloid angiopathy (CAA) is a disorder characterized by amyloid deposition in the walls of leptomeningeal and cortical arteries, arterioles, and less often capillaries and veins of the central nervous...
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Molecular Genetic Aspects of Alzheimer's Disease

Han SH

Alzheimer's disease (AD), the cause of one of the most common types of dementia, is pathologically characterized by cholinergic deficits, extracellular amyloid deposit, intraneuronal neurofibrillary tangles, gliosis, and neuronal and...
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Immunohistochemical Study on GTP-binding Rab6 Expression in the Hippocampal Cortices of the Alzheimer Brain

Cheon YH, Kang YJ, Lee JH, Pyo JS, Baik TK

  • KMID: 2092863
  • Korean J Anat.
  • 2005 Oct;38(5):451-459.
The ras-related GTP binding protein, rab6, is located in late Golgi compartment. Modulation of beta-and gamma-secretase activity may lead to production of beta-amyloid fragments that are ultimately deposited in senile...
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A Case of Secondary Amyloid Goiter with Hypothyroidism

Park CK, Yang YC, Lee CH, Jeong JR, Kim DH, Suh JH, Park JH, Kim YI

  • KMID: 2199570
  • J Korean Soc Endocrinol.
  • 1999 Dec;14(4):752-756.
Amyloidosis results from the deposition of insoluble, fibrous amyloid proteins, nearly always in the extracellular spaces of organs and tissues. There are several varieties of amyloidosis, each of which is...
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