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The gene expression signature of metabolic dysfunction- associated steatotic liver disease from a multiomics perspective

Pirola CJ, Sookoian S

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Personalized medicine in nonalcoholic fatty liver disease

Pirola CJ, Sookoian S

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Repurposing drugs to target nonalcoholic steatohepatitis: Auranofin, a gold-organic molecule complex for the treatment of a specifc complex trait

Pirola CJ, Sookoian S

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Genetics in non-alcoholic fatty liver disease: The role of risk alleles through the lens of immune response

Sookoian S, Pirola CJ

The knowledge on the genetic component of non-alcoholic fatty liver disease (NAFLD) has grown exponentially over the last 10 to 15 years. This review summarizes the current evidence and the...
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Genetic predisposition in nonalcoholic fatty liver disease

Sookoian S, Pirola CJ

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has reached global epidemic proportions. Although the disease is relatively benign in the early stages, when...
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Precision medicine in nonalcoholic fatty liver disease: New therapeutic insights from genetics and systems biology

Sookoian S, Pirola CJ

Despite more than two decades of extensive research focusing on nonalcoholic fatty liver disease (NAFLD), no approved therapy for steatohepatitis—the severe histological form of the disease—presently exists. More importantly, new...
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