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Synthesized TGF-beta s in RPE regulates cellular proliferation

Lee SC, Seong GJ, Kim SH, Kwon OW

Retinal pigment epithelial (RPE) cells transdifferentiate in culture, a transition which is accompanied by a shift in biological activity. The present study investigates whether transforming growth factor (TGF)-beta has the...
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Sensitivity of CD95-induced apoptosis in different proliferative status of human retinal pigment epithelial cells

Chang JH, Kang SW, Ham DI

It is known that CD95 (APO-1/Fas) is expressed on the cell surface, and apoptotic cell death can be induced by the CD95 ligation in the cultured, proliferating human retinal pigment...
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The effects of ascorbic acid on free radical injury in cultured retinal pigment epithelial cells

Woo KI, Lee J

This study was conducted to investigate the effect of ascorbic acid on oxidative injury of cultured porcine retinal pigment epithelial (RPE) cells induced by t-butylhydroperoxide. The porcine RPE cells were...
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Protective Effects of Epigallocatechin Gallate after UV Irradiation in Cultured Human Retinal Pigment Epithelial Cells

Yang SW, Lee BR, Koh JW

PURPOSE: To evaluate the protective effects of Epigallocatechin gallate (EGCG) against UV irradiation in cultured human retinal pigment epithelial (RPE) cells. METHODS: UV irradiation was produced by a UV...
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The effect of telomerase expression on the escape from M2 crisis in virus-transformed human retinal pigment epithelial cells

Park JK, Kim BH, Han YS, Park IK

  • KMID: 1081459
  • Exp Mol Med.
  • 2002 May;34(2):107-113.
Transformation with viral oncogene extends the lifespan of normal cells beyond replicative senescence called M1, but most of them eventually succumb to second crisis called M2 when telomeres become critically...
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Role of HGF/c-Met in Serum-Starved ARPE-19 Cells

Jun EJ, Kim HS, Kim YH

PURPOSE: Hepatocyte growth factor (HGF) and its receptor (HGFR/c-Met) regulate motility, mitogenesis, and morphogenesis in a cell type-dependent fashion. We report the role of HGF and c-Met on stress-induced...
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