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A New Direction of Cancer Classification: Positive Effect of Low-Ranking MicroRNAs

Li F, Piao M, Piao Y, Li M, Ryu KH

Objectives Many studies based on microRNA (miRNA) expression profiles showed a new aspect of cancer classification. Because one characteristic of miRNA expression data is the high dimensionality, feature selection methods have...
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Cervical Cord Hemorrhage in Cerebral Cavernous Malformations

Wang Z, Wu H, Piao Y, Wang C

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Pharmacotherapeutic Strategies to Prevent Relapse in Schizophrenia

Kim J, Piao Y, Shen Q, Chung YC

Successful treatment is very high in patients with first episode schizophrenia (FES). On the other hand, the problem is a frequent relapse often caused by non-compliance. The non-compliance rate in...
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Peroneal Flap: Clinical Application and Cadaveric Study

Ha Y, Yeo KK, Piao Y, Oh SH

BACKGROUND: The goal of this study was to investigate the anatomy of the peroneal artery and its perforators, and to report the clinical results of reconstruction with peroneal artery perforator...
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The Development of the Brooding Scale

Kim JH, Piao Y, Kim WS, Park JJ, Kang NI, Lee KH, Chung YC

OBJECTIVE: The purpose of this study was to develop a Brooding Scale (BS) and to confirm its psychometric properties. METHODS: A preliminary questionnaire was developed based on a literature review and...
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Influenza M1 Virus-Like Particles Consisting of Toxoplasma gondii Rhoptry Protein 4

Lee SH, Lee DH, Piao Y, Moon EK, Quan FS

Toxoplasma gondii infections occur throughout the world, and efforts are needed to develop various vaccine candidates expressing recombinant protein antigens. In this study, influenza matrix protein (M1) virus-like particles (VLPs)...
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miR-24-mediated knockdown of H2AX damages mitochondria and the insulin signaling pathway

Jeong JH, Cheol Kang Y, Piao Y, Kang S, Pak YK

Mitochondrial deficits or altered expressions of microRNAs are associated with the pathogenesis of various diseases, and microRNA-operated control of mitochondrial activity has been reported. Using a retrovirus-mediated short-hairpin RNA (shRNA)...
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Five-year investigation of a large orthodontic patient population at a dental hospital in South Korea

Piao Y, Kim SJ, Yu HS, Cha JY, Baik HS

OBJECTIVE: The purpose of this study was to investigate the characteristics of orthodontic patients at Yonsei Dental Hospital from 2008 to 2012. METHODS: We evaluated Angle's classification from molar relationships, classification...
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A Novel Therapeutic Effect of a New Variant of CTLA4-Ig with Four Antennas That Are Terminally Capped with Sialic Acid in the CTLA4 Region

Piao Y, Yun SY, Kim HS, Park BK, Ha HC, Fu Z, Jang JM, Back MJ, Shin IC, Won JH, Kim DK

Rheumatoid arthritis (RA) is a multifactorial immune-mediated disease, the pathogenesis of which involves different cell types. T-cell activation plays an important role in RA. Therefore, inhibiting T-cell activation is one...
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Paranasal Sinus Invasion in Nasopharyngeal Carcinoma after Intensity-Modulated Radiotherapy

Cao C, Jiang F, Jin Q, Jin T, Huang S, Hu Q, Chen Y, Piao Y, Hua Y, Feng X, Chen X

PURPOSE: The aim of this study is to evaluate the prognostic significance of paranasal sinus invasion for nasopharyngeal carcinoma (NPC) and its suitable position in the T classification. MATERIALS AND METHODS:...
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Mitochondrial Ribosomal Protein L14 Promotes Cell Growth and Invasion by Modulating Reactive Oxygen Species in Thyroid Cancer

Kim HJ, Nguyen QK, Jung SN, Lim MA, Oh C, Piao Y, Jin Y, Kim JH, Kim YI, Kang YE, Chang JW, Won HR, Koo BS

Objectives. The mitochondrial ribosomal protein L14 (MRPL14) is encoded by a nuclear gene and participates in mitochondrial protein translation. In this study, we aimed to investigate the role of MRPL14...
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Positive Effect of Baby-Friendly Hospital Initiatives on Improving Mothers' Intention for Successful Breastfeeding in Korea

Park HW, Ryu KH, Piao Y, Li P, Hong JS, Kim HB, Chung H, Hoh JK, Kim YJ

BACKGROUND: In Korea, the breastfeeding (BF) rate of infants aged 6 months or more is drastically decreasing, and this phenomenon is particularly worrisome for the future health of the population....
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