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Analysis of Gene Expression in Primary Hepatocellular Carcinoma Using Differentially Displayed Reverse Transcriptase Polymerase Chain Reaction

Lee YC, Hur W, Choi JE, Piao LS, Hong SW, Bae SH, Choi JY, Yoon SK

BACKGROUND/AIMS: The investigation of a specific tumor marker for hepatocellular carcinoma (HCC) is needed to examine the carcinogenesis and to select the patients for treatment options. The aim of this...
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In vitro Culture of Hepatitis C Virus (HCV) Using Immortalized Hepatocyte

Choi JE, Hur W, Shin JY, Piao LS, Yoon SK

  • KMID: 1767619
  • Korean J Gastroenterol.
  • 2008 Sep;52(3):150-160.
BACKGROUND/AIMS: It is essential to develop an in vitro culture model of primary hepatocytes for the study of hepatocellular function and the pathogenesis of hepatitis C virus (HCV) infection. In...
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Functional characterization of human oncoprotein gankyrin in Zebrafish

Kim SY, Hur W, Choi JE, Kim D, Wang JS, Yoon HY, Piao LS, Yoon SK

Gankyrin is an oncoprotein containing seven ankyrin repeats that is overexpressed in hepatocellular carcinoma (HCC). Gankyrin binds to Mdm2, which results in accelerated ubiquitylation via degradation of p53, and it...
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