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Recent advances of photodynamic therapy for biliary tract cancer

Cheon YK

The prognosis of bile duct cancer (BDC) is limited due to tumor spread along the biliary tree leading to refractory obstructive cholestasis, cholangitis, and liver failure. Palliation with biliary endoprostheses...
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Photodynamic Diagnosis and Therapy for Peritoneal Carcinomatosis from Gastrointestinal Cancers: Status, Opportunities, and Challenges

Kim HI, Wilson BC

Selective accumulation of a photosensitizer and the subsequent response in only the lightirradiated target are advantages of photodynamic diagnosis and therapy. The limited depth of the therapeutic effect is a...
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Pigmentary Changes Following Photodynamic Therapy with 5-aminolevulinic Acid or Methyl Aminolevulinate Cream

Kim ST, Park JB, Kim JH, Lee KH, Han SH, Yang JS, Suh KS, Jang MS

  • KMID: 2245844
  • Korean J Dermatol.
  • 2015 Sep;53(8):604-611.
BACKGROUND: Several side effects such as pain, erythema, and hyperpigmentation have been reported following photodynamic therapy (PDT). OBJECTIVE: We sought to compare the pigmentary changes induced by PDT with 5-aminolevulinic acid...
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Photodynamic Therapy for Hilar Bile Duct Cancer

Lee SH

  • KMID: 2448439
  • Korean J Pancreas Biliary Tract.
  • 2014 Apr;19(2):71-78.
Hilar cholangiocarcinoma is a fatal malignancy leading to high mortality rate despite recent therapeutic advances, and the photodynamic therapy has been noted as an emerging palliative strategy for the hilar...
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The Effects of Photodynamic Therapy in Upper-Gastrointestinal Malignant Diseases

Kim KH, Park JJ

  • KMID: 2053430
  • Gut Liver.
  • 2010 Sep;4(Suppl 1):S39-S43.
Photodynamic therapy (PDT) is a promising new modality that utilizes the combination of a photosensitizing chemical and visible light for the management of various solid malignancies, including gastrointestinal (GI) cancer....
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In vivo study of photodynamic therapy using a new photosensitizer, 9-hydroxypheophorbide-a and 670 nm diode laser on HT-3 cervical cancer cell

Kim JS

  • KMID: 2273742
  • Korean J Obstet Gynecol.
  • 2009 Jul;52(7):734-745.
OBJECTIVE: During the last several years, such as Photofrin(R), Photogem(R), HpD, and 5-aminolevulenic acid (ALA) has been used as photosensitizers for a wide range of malignant tumors as well as...
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The anticancer effect and mechanism of photodynamic therapy using a new photosensitizer and diode laser on cervical cancer cell

Kim JS, Park CH, Chung PS

  • KMID: 2273705
  • Korean J Obstet Gynecol.
  • 2009 Apr;52(4):437-446.
OBJECTIVE: During the last several years, such as Photofrin(R), Photogem(R), HpD, and 5-aminolevulenic acid (ALA) has been used as photosensitizers for a wide range of malignant tumors as well as...
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Photodynamic Therapy

Jheon S

Clinical photodynamic therapy was introduced in the 1970s and has been shown to be an effective treatment modality in a variety of fields in oncology. Photodynamic therapy (PDT) is a...
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Delivery of Photosensitizers for Photodynamic Therapy

Park S

  • KMID: 782862
  • Korean J Gastroenterol.
  • 2007 May;49(5):300-313.
Photodynamic therapy (PDT) has been used to treat several types of cancer, and comprises intravascular administration of photosensitizer, uptake by cancer cells, and followed by irradiation of light of appropriate...
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Photodynamic Therapy(PDT) for Early Glottic Cancer which was Recurred after Initial Treatment Modality

Chung PS, Moon JH, Park E

  • KMID: 2276635
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Apr;49(4):468-471.
Photodynamic therapy (PDT) is a method used to treat cancer early by irradiating laser with suitable wavelength after injection of a photosensitizer. We introduce the result of PDT for treating...
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The Anticancer Effect and Mechanism of Photodynamic Therapy Using 9-Hydroxypheophorbide-alpha and 630 nm Diode Laser on Heterotransplanted Squamous Cell Carcinoma of Head and Neck

Kim HG, Chung PS, Kim SH, Lee SH, Rhee CK

  • KMID: 2276419
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Jun;48(6):765-770.
BACKGROUND AND OBJECTIVES: The 9-Hydroxypheophorbide-alpha(9-HpbD-alpha) is a new photosensitizer, derived from a plant in water. We conducted a series of experiments in vivo to evaluate the anticancer effect and mechanism...
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Interstitial Photodynamic Therapy (PDT) Set-up for Treating Solid Tumor Using Laser Diode

Kim KH, Kim JK

  • KMID: 1591057
  • Korean J Med Phys.
  • 2005 Jun;16(2):104-109.
Photodynamic therapy (PDT) is one of the expectable current cure operation methods. Tumor tissue is treated by abundant oxygen in a body and generated singlet or free radical from exterior...
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The Photodynamic Therapy using 5-Aminolevulinic Acid(ALA): The Study of the Anti-Tumor Effect on in vitro and in vivo Experiments

Kim JS, Chung PS, Lee SJ, Oh CH, Chung SY, Park JY, Kim YS

  • KMID: 2037123
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Feb;48(2):234-240.
BACKGROUND AND OBJECTIVES: ALA is a precursor of heme and converted to protoporphyrin IX used as effective photosensitizer. The aim of this study was to find the ideal concentration and...
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Endoscopic Photodynamic Diagnosis (PDD) Using Oral 5-aminolevulinic Acid in Gastrointestinal Cancer and Dysplastic Lesions

Cheon YK, Cho YD, Kim JO, Cho JY, Lee JS, Kim YS, Lee MS, Shim CS

  • KMID: 1613251
  • Korean J Gastrointest Endosc.
  • 2003 Feb;26(2):73-78.
BACKGROUND/AIM: Endoscopic screening for the detection of premalignant high-grade dysplasia remains time consuming and is subject to sampling error. We performed this study to determine the clinical usefulness of laser...
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Photodynamic Therapy Of Premalignant And Malignant Lesions In Oral And Maxillofacial Surgery

Oh JH, Kubler A, Zoller JE

  • KMID: 2137036
  • J Korean Assoc Oral Maxillofac Surg.
  • 2002 Jun;28(3):234-238.
Photodynamic therapy (PDT) is based on a photochemical reaction which is initiated by light activation of a photosensitizer. The photosensitizer accumulates more in tumor tissues than in normal tissues and...
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Anti-retroviral effect of chlorophyll derivatives (CpD-D) by photosensitization

Lee M, Lee Y

A new photosensitizer, CpD(chlorophyll derivatives), previously reported as a promising agent for tumor therapy, was studied to determine its inhibitory effects on Gross leukemia virus(GLV), a mouse retrovirus isolated from...
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Chlorophyll derivatives: a new photosensitizer for photodynamic therapy of cancer in mice

Park YJ, Lee WY, Hahn BS, Han MJ, Yang WI, Kim BS

The in vivo photosensitizing efficacy of chlorophyll derivatives(CpD), which had been developed as a new photosensitizer, was compared with that of hematoporphyrin derivatives (HpD). A murine tumor model implanted...
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