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Egg phospholipids exert an inhibitory effect on intestinal cholesterol absorption in mice

Lee Y, Han CY, Bae M, Park YK, Lee JY

BACKGROUND/OBJECTIVES: Consumption of cholesterol-rich foods, such as eggs, has a minimal effect on circulating cholesterol levels in healthy humans. To gain insight, we investigated whether phospholipids rich in eggs (EPL)...
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The Effect of 1-Propanol on the Rotational Mobility of n-(9-Anthroyloxy) stearic acid in Outer Monolayers of Neuronal and Model Membranes

Ahn TY, Jin SD, Yang HJ, Yoon CD, Kim MK, An TK, Bae YJ, Seo SJ, Kim GS, Bae MK, Bae SK, Jang HO

The aim of this study was to provide a basis for the molecular mechanism underlying the pharmacological action of ethanol. We studied the effects of 1-propanol on the location of...
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Sphingosylphosphorylcholine Induces Thrombospondin-1 Secretion in MCF10A Cells via ERK2

Kang JH, Kim HJ, Park MK, Lee CH

Sphingosylphosphorylcholine (SPC) is one of the bioactive phospholipids that has many cellular functions such as cell migration, adhesion, proliferation, angiogenesis, and Ca²⁺ signaling. Recent studies have reported that SPC induces...
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Nutritional Factors Affecting Mental Health

Lim SY, Kim EJ, Kim A, Lee HJ, Choi HJ, Yang SJ

Dietary intake and nutritional status of individuals are important factors affecting mental health and the development of psychiatric disorders. Majority of scientific evidence relating to mental health focuses on depression,...
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The use of artificial pulmonary surfactant in neonatal respiratory distress

Choi YS

Pulmonary surfactant instillation is the treatment of choice in neonatal respiratory distress syndrome. The development of artificial surfactant has three decades of history. Animal-derived artificial surfactant is used in most...
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Hair Growth Promoting Potential of Phospholipids Purified from Porcine Lung Tissues

Choi SH, Moon JS, Jeon BS, Jeon YJ, Yoon BI, Lim CJ

BP201, porcine lung tissue-derived phospholipids, consists of phosphatidylcholine as a major phospholipid species. BP201 promoted hair growth after application onto the shaved backs of BALB/c and C3H mice. Its effect...
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Efficacy of Surfactant-TA, Calfactant and Poractant Alfa for Preterm Infants with Respiratory Distress Syndrome: A Retrospective Study

Jeon GW, Oh M, Sin JB

PURPOSE: To compare the efficacy of the new drug calfactant with the commonly used drugs surfactant-TA and poractant alfa. MATERIALS AND METHODS: A total of 332 preterm infants at 24-31 weeks'...
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Nutritional roles and health effects of eggs

Yang EJ, Lee YE, Moon HK

PURPOSE: The aim of this study is to examine the effects of egg consumption and suggest proper guidelines for consumption of eggs by determining the relationship between eggs and cholesterol. METHODS:...
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Decreasing Effect of Lidocaine.HCl on the Thickness of the Neuronal and Model Membrane

Park SM, Park JS, Kim JH, Baek JH, Yoon TG, Lee DK, Ryu WH, Chung IK, Sohn UD, Jang HO, Yun I

This study examined the mechanism of action of a local anesthetic, lidocaine.HCl. Energy transfer between the surface fluorescent probe, 1-anilinonaphthalene-8-sulfonic acid, and the hydrophobic fluorescent probe, 1,3-di(1-pyrenyl) propane, was used...
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4-Week repeated oral dose toxicity study of 1,4-dichlorobutane in rats

Yu WJ, Lee IC, Lee J, Lee SM, Kim SH, Baek HS, Moon C, Kim SH, Chung YH, Kim JC

  • KMID: 2312103
  • Lab Anim Res.
  • 2013 Mar;29(1):48-54.
The present study investigated the potential subacute toxicity of 1,4-dichlorobutane by a 4-week repeated oral dose in Sprague-Dawley rats. The test article was administered once daily by gavage to male...
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Characterization of anti-factor VIII antibody in a patient with acquired hemophilia A

Oh J, Lim Y, Jang MJ, Huh JY, Shima M, Oh D

Acquired hemophilia A (AHA) is a bleeding disorder caused by the development of an auto-antibody against endogenous factor VIII (FVIII). In this study, the epitope of the autoantibody was identified...
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Synthesis of Ultrasound Contrast Agent: Characteristics and Size Distribution Analysis

Lee HJ, Yoon TJ, Yoon YI

  • KMID: 2096944
  • J Korean Soc Ultrasound Med.
  • 2013 Mar;32(1):59-65.
PURPOSE: The purpose of this study is to establish the methodology regarding synthesis of ultrasound contrast agent imaging, and to evaluate the characteristics of the synthesized ultrasound contrast agents, including...
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Current consensus and guidelines of contrast enhanced ultrasound for the characterization of focal liver lesions

Jang JY, Kim MY, Jeong SW, Kim TY, Kim SU, Lee SH, Suk KT, Park SY, Woo HY, Kim SG, Heo J, Baik SK, Kim HS, Tak WY

The application of ultrasound contrast agents (UCAs) is considered essential when evaluating focal liver lesions (FLLs) using ultrasonography (US). Microbubble UCAs are easy to use and robust; their use poses...
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Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases

Park MH, Igarashi K

  • KMID: 2170679
  • Biomol Ther.
  • 2013 Jan;21(1):1-9.
Polyamines, putrescine, spermidine and spermine, are ubiquitous in living cells and are essential for eukaryotic cell growth. These polycations interact with negatively charged molecules such as DNA, RNA, acidic proteins...
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Advent of Novel Phosphatidylcholine-Associated Nonsteroidal Anti-Inflammatory Drugs with Improved Gastrointestinal Safety

Lim YJ, Dial EJ, Lichtenberger LM

  • KMID: 2053509
  • Gut Liver.
  • 2013 Jan;7(1):7-15.
The mucosa of the gastrointestinal (GI) tract exhibits hydrophobic, nonwettable properties that protect the underlying epithelium from gastric acid and other luminal toxins. These biophysical characteristics appear to be attributable...
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The Effect of Lidocaine.HCl on the Fluidity of Native and Model Membrane Lipid Bilayers

Park JS, Jung TS, Noh YH, Kim WS, Park WI, Kim YS, Chung IK, Sohn UD, Bae SK, Bae MK, Jang HO, Yun I

The purpose of this study is to investigated the mechanism of pharmacological action of local anesthetic and provide the basic information about the development of new effective local anesthetics. Fluorescent...
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Anesthetic Management of Whole-Lung Lavage Using Propofol-Remifentanil in a Patient with Pulmonary Alveolar Proteinosis

Lee JH, Chung CJ, Oh JN, Ko BJ, Choi SR

Pulmonary alveolar proteinosis (PAP) is characterized by the progressive accumulation of phospholipids and proteins within the alveolar sacs without producing an inflammatory response. Whole-lung lavage (WLL) is performed as the...
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The Effect of Methanol on the Structural Parameters of Neuronal Membrane Lipid Bilayers

Joo HJ, Ahn SH, Lee HR, Jung SW, Choi CW, Kim MS, Bae MK, Chung IK, Bae SK, Jang HO, Yun I

The structures of the intact synaptosomal plasma membrane vesicles (SPMVs) isolated from bovine cerebral cortexs, and the outer and the inner monolayer separately, were evaluated with 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1,3-di(1-pyrenyl)propane...
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A Case of Propofol-Induced Oropharyngeal Angioedema and Bronchospasm

You BC, Jang AS, Han JS, Cheon HW, Park JS, Lee JH, Park SW, Kim DJ, Park CS

Propofol (2,6-diisopropylphenol) is an ultrashort-acting sedative agent with sedative and amnestic effects that is used not only for anesthesia but also for sedation during minor outpatient procedures and endoscopic examinations....
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Appraisal of Antihyperlipidemic Activities of Lentinus lepideus in Hypercholesterolemic Rats

Yoon KN, Lee JS, Kim HY, Lee KR, Shin PG, Cheong JC, Yoo YB, Alam N, Ha TM, Lee TS

  • KMID: 2312655
  • Mycobiology.
  • 2011 Dec;39(4):283-289.
The wild edible mushroom, Lentinus lepideus has recently been cultivated for commercial use in Korea. While the mushroom has been widely used for nutritional and medicinal purposes, the possible anti-hyperlipidemic...
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