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Eosinophilic esophagitis: current understanding and evolving concepts

Philpott H, Kweh B, Thien F

Eosinophilic esophagitis (EoE) is now considered to represent a form of food allergy and this is demonstrated by a response to elimination diet in many patients. A critical additional factor...
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Histologic improvement after 6 weeks of dietary elimination for eosinophilic esophagitis may be insufficient to determine efficacy

Philpott H, Dellon E

BACKGROUND: Elimination diets are used to treat eosinophilic esophagitis (EoE), with success (remission) defined at endoscopy and oesophageal biopsy as fewer than 15 eosinophils per high power field (HPF). Response...
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Irritable bowel syndrome - An inflammatory disease involving mast cells

Philpott H, Gibson P, Thien F

Irritable bowel syndrome (IBS) is traditionally defined as a functional disorder - that is the presence of symptoms in the absence of demonstrable pathological abnormalities. In recent times, low grade...
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