- Differential Activation of Macrophages Based on Their Environment in Advanced Age
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Lee DY, Lim JS, Cho KA
- KMID: 2468141
- Chonnam Med J.
- 2020 Jan;56(1):12-19.
- doi: 10.4068/cmj.2020.56.1.12
The macrophage displays functional and phenotypic diversity, which appears, in no small part, to stem from the ability of macrophages to adapt functionally to changes in their tissue microenvironment. Here,... -
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- Scavenger Receptor Class A to E Involved in Various Cancers
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Ryu S, Howland A, Song B, Youn C, Song PI
- KMID: 2468139
- Chonnam Med J.
- 2020 Jan;56(1):1-5.
- doi: 10.4068/cmj.2020.56.1.1
Scavenger receptors typically bind to multiple ligands on a cell surface, including endogenous and modified host-derived molecules and microbial pathogens. They promote the elimination of degraded or harmful substances such... -
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- Macrophages in xenotransplantation
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Kim JY
- KMID: 2468157
- Korean J Transplant.
- 2019 Dec;33(4):74-82.
- doi: 10.4285/jkstn.2019.33.4.74
Xenotransplantation refers to organ transplantation across species. Immune rejection of xenografts is stronger and faster than that of allografts because of significant molecular differences between species. Recent studies have revealed... -
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- PD-1: A Negative Regulator of Phagocytosis by Tumour-Associated Macrophages in Colon Cancer
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Islam Tultul MS, Koh YS
- KMID: 2468029
- J Bacteriol Virol.
- 2019 Dec;49(4):230-236.
- doi: 10.4167/jbv.2019.49.4.230
Programmed cell death protein 1 (PD-1) is an immuno-inhibitory cell surface receptor protein of the myeloid, and lymphoid cell. PD-L1 is the ligand of PD-1, which is abundant in different... -
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- Aralia cordata Extract Activates NF-κB and MAPK Signaling Pathways and Induces Pro-inflammatory Changes in RAW264.7 Macrophages
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Seo DW, Cho YI, Yi YJ, Lee SM
- KMID: 2468022
- J Bacteriol Virol.
- 2019 Dec;49(4):153-161.
- doi: 10.4167/jbv.2019.49.4.153
Macrophages play essential roles in innate immune responses by producing various immune mediators. Therefore, modulating macrophage function is an attractive strategy to treat immune disorders. Aralia cordata var. continentalis (AC),... -
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- Etoposide Induces Mitochondrial Dysfunction and Cellular Senescence in Primary Cultured Rat Astrocytes
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Bang M, Kim DG, Gonzales E, Kwon KJ, Shin CY
- KMID: 2462880
- Biomol Ther.
- 2019 Nov;27(6):530-539.
- doi: 10.4062/biomolther.2019.151
Brain aging is an inevitable process characterized by structural and functional changes and is a major risk factor for neurodegenerative diseases. Most brain aging studies are focused on neurons and... -
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- Safety and efficacy of polycaprolactone copolymer nanosphere hydrogel injected into the scalp dermal tissue of rats
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Lee SJ, Lee WS, Chung CH
- KMID: 2464286
- Arch Aesthetic Plast Surg.
- 2019 Oct;25(4):147-153.
- doi: 10.14730/aaps.2019.01739
BACKGROUND: Currently, dermal fillers need to be 25 µm or larger to reduce in vivo degradation by macrophages. However, the large size of fillers may cause side effects, including interruption... -
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- Generation of Retinal Pigmented Epithelium-Like Cells from Pigmented Spheres Differentiated from Bone Marrow Stromal Cell-Derived Neurospheres
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Kadkhodaeian HA, Tiraihi T, Ahmadieh H, Ziaei H, Daftarian , Taheri T
- KMID: 2449236
- Tissue Eng Regen Med.
- 2019 Jun;16(3):253-263.
- doi: 10.1007/s13770-019-00183-1
BACKGROUND: Retinal degeneration causes blindness, and cell replacement is a potential therapy. The purpose of this study is to formation of pigmented neurospheres in a simple medium, low-cost, high-performance manner... -
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- Combination Treatment of Stereotactic Body Radiation Therapy and Immature Dendritic Cell Vaccination for Augmentation of Local and Systemic Effects
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Choi CW, Jeong MH, Park YS, Son CH, Lee HR, Koh EK
- KMID: 2464393
- Cancer Res Treat.
- 2019 Apr;51(2):464-473.
- doi: 10.4143/crt.2018.186
PURPOSE: The purpose of this study was to investigate the efficacy of stereotactic body radiation therapy (SBRT) as a tumor-associated antigen (TAA) presentation method for dendritic cell (DC) sensitization and... -
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- IL-12 Enhances Immune Response by Modulation of Myeloid Derived Suppressor Cells in Tumor Microenvironment
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Choi JN, Sun EG, Cho SH
- KMID: 2432253
- Chonnam Med J.
- 2019 Jan;55(1):31-39.
- doi: 10.4068/cmj.2019.55.1.31
Myeloid derived suppressor cells (MDSCs) are a heterogenous population of immature cells that play a critical role in tumor associated immune suppression. In tumor conditions, the population of MDSCs increases.... -
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- CRISPR/Cas9-mediated knockout of CD47 causes hemolytic anemia with splenomegaly in C57BL/6 mice
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Kim JI, Park JS, Kwak J, Lim HJ, Ryu SK, Kwon E, Han KM, Nam KT, Lee HW, Kang BC
- KMID: 2459309
- Lab Anim Res.
- 2018 Dec;34(4):302-310.
- doi: 10.5625/lar.2018.34.4.302
CD47 (integrin-associated protein), a multi-spanning transmembrane protein expressed in all cells including red blood cells (RBCs) and leukocytes, interacts with signal regulatory protein α (SIRPα) on macrophages and thereby inhibits... -
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- Effect of Various Agents on Oral Bacterial Phagocytosis in THP-1 Cells
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Song Y, Lee HA, Na HS, Chung J
- KMID: 2437339
- Int J Oral Biol.
- 2018 Dec;43(4):217-222.
- doi: 10.11620/IJOB.2018.43.4.217
Phagocytosis is a fundamental process in which phagocytes capture and ingest foreign particles including pathogenic bacteria. Several oral pathogens have anti-phagocytic strategies, which allow them to escape from and survive... -
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- Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells
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Chae JB, Rho CR, Shin JA, Lyu J, Kang S
- KMID: 2418154
- Korean J Ophthalmol.
- 2018 Aug;32(4):328-338.
- doi: 10.3341/kjo.2017.0079
PURPOSE: Anti-vascular endothelial growth factor (VEGF) agents have been used for the last 10 years, but their safety profile, including cytotoxicity against various ocular cells such as retinal pigment epithelial... -
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- Phagocytic Roles of Glial Cells in Healthy and Diseased Brains
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Jung YJ, Chung WS
- KMID: 2420385
- Biomol Ther.
- 2018 Jul;26(4):350-357.
- doi: 10.4062/biomolther.2017.133
Glial cells are receiving much attention since they have been recognized as important regulators of many aspects of brain function and disease. Recent evidence has revealed that two different glial... -
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- Osteopontin Peptide Icosamer Containing RGD and SLAYGLR Motifs Enhances the Motility and Phagocytic Activity of Microglia
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Kim ID, Lee H, Jin YC, Lee JK
- KMID: 2398422
- Exp Neurobiol.
- 2017 Dec;26(6):339-349.
- doi: 10.5607/en.2017.26.6.339
Osteopontin (OPN) is a secreted glycoprotein that is expressed in various tissues, including brain, and mediates a wide range of cellular activities. In a previous study, the authors observed the... -
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- Association of Single-Nucleotide Polymorphisms of the MBL2 with Atopic Dermatitis in Korean Patients
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Kim JS, Lee SY, Hahn HJ, Lee YB, Yu DS, Kim JW
- KMID: 2388908
- Ann Dermatol.
- 2017 Oct;29(5):571-577.
- doi: 10.5021/ad.2017.29.5.571
BACKGROUND: Human mannose-binding lectin (MBL) is a serum lectin taking part in the innate immunity by opsonizing various microorganisms for phagocytosis. The MBL serum concentration is affected by several single-nucleotide... -
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- Inhibition by miR-410 facilitates direct retinal pigment epithelium differentiation of umbilical cord blood-derived mesenchymal stem cells
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Choi SW, Kim JJ, Seo MS, Park SB, Shin TH, Shin JH, Seo Y, Kim HS, Kang KS
- KMID: 2412588
- J Vet Sci.
- 2017 Mar;18(1):59-65.
- doi: 10.4142/jvs.2017.18.1.59
Retinal pigment epithelium (RPE) is a major component of the eye. This highly specialized cell type facilitates maintenance of the visual system. Because RPE loss induces an irreversible visual impairment,... -
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- Familial Hemophagocytic Lymphohistiocytosis Type 2 in a Korean Infant With Compound Heterozygous PRF1 Defects Involving a PRF1 Mutation, c.1091T>G
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Kim MS, Cho YU, Jang S, Seo EJ, Im HJ, Park CJ
- KMID: 2373636
- Ann Lab Med.
- 2017 Mar;37(2):162-165.
- doi: 10.3343/alm.2017.37.2.162
No abstract available. -
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- Impaired Antioxidant Ability of HDL and More Oxidized LDL are associated with Male Patients with Atrial Fibrillation
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Kim SJ, Shin DG, Kim JR, Cho KH
- KMID: 2366139
- J Lipid Atheroscler.
- 2016 Dec;5(2):145-154.
- doi: 10.12997/jla.2016.5.2.145
OBJECTIVE: Atrial fibrillation (AF) is a common arrhythmia which is generally more prevalent in the elderly population. However, the new onset of AF is frequently found in young populations. In... -
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- Inhibitory effect of red ginseng acidic polysaccharide from Korean red ginseng on phagocytic activity and intracellular replication of Brucella abortus in RAW 264.7 cells
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Bernardo Reyes AW, Simborio H, Hop HT, Arayan LT, Min WG, Lee HJ, Rhee MH, Chang HH, Kim S
- KMID: 2413130
- J Vet Sci.
- 2016 Sep;17(3):315-321.
- doi: 10.4142/jvs.2016.17.3.315
Korean red ginseng (KRG) has long been used in traditional Korean and Oriental medicine. However, the anti-bacterial mechanism and therapeutic efficiency of KGR for intracellular Brucella infection are still unclear.... -
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