- Differentially Expressed Genes in Period 2-Overexpressing Mice Striatum May Underlie Their Lower Sensitivity to Methamphetamine Addiction-Like Behavior
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Sayson LV, Kim M, Jeon SJ, Perez Custodio RJ, Lee HJ, Ortiz DM, Cheong JH, Kim HJ
- KMID: 2529889
- Biomol Ther.
- 2022 May;30(3):238-245.
- doi: 10.4062/biomolther.2021.184
Previous reports have demonstrated that genetic mechanisms greatly mediate responses to drugs of abuse, including methamphetamine (METH). The circadian gene Period 2 (Per2 ) has been previously associated with differential... -
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- 4-F-PCP, a Novel PCP Analog Ameliorates the Depressive-Like Behavior of Chronic Social Defeat Stress Mice via NMDA Receptor Antagonism
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Ortiz DMD, Kim M, Lee HJ, Botanas CJ, Perez Custodio RJ, Sayson LV, Campomayor NB, Lee C, Lee YS, Cheong JH, Kim HJ
- KMID: 2539592
- Biomol Ther.
- 2023 Mar;31(2):227-239.
- doi: 10.4062/biomolther.2022.159
Major depressive disorder is a leading cause of disability in more than 280 million people worldwide. Monoamine-based antidepressants are currently used to treat depression, but delays in treatment effects and... -
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