- The N- and C-terminal domains of parathyroid hormone-related protein affect differently the osteogenic and adipogenic potential of human mesenchymal stem cells
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Casado-Diaz A, Santiago-Mora R, Quesada JM
- KMID: 983981
- Exp Mol Med.
- 2010 Feb;42(2):87-98.
- doi: 10.3858/emm.2010.42.2.010
Parathyroid hormone-related protein (PTHrP) is synthesized by diverse tissues, and its processing produces several fragments, each with apparently distinct autocrine and paracrine bioactivities. In bone, PTHrP appears to modulate bone... -
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- Activation of nicotinic acetylcholine receptor prevents the production of reactive oxygen species in fibrillar beta amyloid peptide (1-42)-stimulated microglia
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Moon JH, Kim SY, Lee HG, Kim SU, Lee YB
- KMID: 1103583
- Exp Mol Med.
- 2008 Feb;40(1):11-18.
- doi: 10.3858/emm.2008.40.1.11
Recent studies have reported that the "cholinergic anti-inflammatory pathway" regulates peripheral inflammatory responses via alpha7 nicotinic acetylcholine receptors (alpha7 nAChRs) and that acetylcholine and nicotine regulate the expression of proinflammatory... -
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- Role of Corticotrophin-releasing Factor in the Stress-induced Dilation of Esophageal Intercellular Spaces
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Cho YJ, Kim JH, Yim HE, Lee DM, Im SK, Lee KJ
- KMID: 1782119
- J Korean Med Sci.
- 2011 Feb;26(2):279-283.
- doi: 10.3346/jkms.2011.26.2.279
Corticotrophin-releasing factor (CRF) plays a major role in coordinating stress responses. We aimed to test whether blocking endogenous CRF activity can prevent the stress-induced dilation of intercellular spaces in esophageal... -
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- ATP released from beta-amyloid-stimulated microglia induces reactive oxygen species production in an autocrine fashion
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Kim SY, Moon JH, Lee HG, Kim SU, Lee YB
- KMID: 1091077
- Exp Mol Med.
- 2007 Dec;39(6):820-827.
Present study demonstrated that fibrillar beta-amyloid peptide (fAbeta(1-42)) induced ATP release, which in turn activated NADPH oxidase via the P2X(7) receptor (P2X(7)R). Reactive oxygen species (ROS) production in fAbeta(1-42)-treated microglia... -
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