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Comparison of Methods for Collecting Saliva for Pepsin Detection in Patients with Laryngopharyngeal Reflux

Ryu IY, Jung AR, Park JM, Lee YC, Eun YG

BACKGROUND AND OBJECTIVES: To compare the simple spitting method and the Salivette® method of collecting saliva for detecting pepsin in patients with laryngopharyngeal reflux disease (LPRD). SUBJECTS AND METHOD: Thirty-two patients...
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Relationship Between Salivary Pepsin Concentration and Esophageal Mucosal Integrity in Patients With Gastroesophageal Reflux Disease

Li YW, Sifrim D, Xie C, Chen M, Xiao YL

  • KMID: 2395419
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):517-525.
  • doi: 10.5056/jnm16178
BACKGROUND/AIMS: Increased salivary pepsin could indicate an increase in gastro-esophageal reflux, however, previous studies failed to demonstrate a correlation between salivary pepsin concentrations and 24-hour esophageal acid exposure. This study...
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The Role of Pepsin in Laryngopharyngeal Reflux

Lee SH, Jin SM, Johnston N

Laryngopharyngeal reflux (LPR) is a very prevalent condition with a rising incidence. The diagnosis remains challenging and often controversial because the pathophysiology of LPR is often poorly understood and there...
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The Effect of Secretin on Pepsin Secretion in Heidenhain Pouch

Lee SH, Kim CB

  • KMID: 2096305
  • J Korean Surg Soc.
  • 2006 Mar;70(3):161-169.
PURPOSE: This research was done to confirm the effect of secretin on pepsin secretion and to study whether or not feeding can depress the secretin-stimulated pepsin secretion (SSPS) with its...
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