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Alleviation of ascorbic acid-induced gastric high acidity by calcium ascorbate in vitro and in vivo

Lee JK, Jung SH, Lee SE, Han JH, Jo E, Park HS, Heo KS, Kim D, Park JS, Myung CS

Ascorbic acid is one of the most well-known nutritional supplement and antioxidant found in fruits and vegetables. Calcium ascorbate has been developed to mitigate the gastric irritation caused by the...
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Comparison of Methods for Collecting Saliva for Pepsin Detection in Patients with Laryngopharyngeal Reflux

Ryu IY, Jung AR, Park JM, Lee YC, Eun YG

BACKGROUND AND OBJECTIVES: To compare the simple spitting method and the Salivette® method of collecting saliva for detecting pepsin in patients with laryngopharyngeal reflux disease (LPRD). SUBJECTS AND METHOD: Thirty-two patients...
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Relationship Between Salivary Pepsin Concentration and Esophageal Mucosal Integrity in Patients With Gastroesophageal Reflux Disease

Li YW, Sifrim D, Xie C, Chen M, Xiao YL

  • KMID: 2395419
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):517-525.
  • doi: 10.5056/jnm16178
BACKGROUND/AIMS: Increased salivary pepsin could indicate an increase in gastro-esophageal reflux, however, previous studies failed to demonstrate a correlation between salivary pepsin concentrations and 24-hour esophageal acid exposure. This study...
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Pharmacologic Management of Nonvariceal Upper Gastrointestinal Bleeding

Kim JH

Acute non-variceal upper gastrointestinal bleeding, the most common etiology of which is peptic ulcer disease, remains a persistent challenge despite a reduction in both its incidence and mortality. Both pharmacologic...
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The Role of Pepsin in Laryngopharyngeal Reflux

Lee SH, Jin SM, Johnston N

Laryngopharyngeal reflux (LPR) is a very prevalent condition with a rising incidence. The diagnosis remains challenging and often controversial because the pathophysiology of LPR is often poorly understood and there...
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Gastroprotective Effects of Glutinous Rice Extract against Ethanol-, Indomethacin-, and Stress-induced Ulcers in Rats

Song DU, Jang MS, Kim HW, Yoon HJ, Chay KO, Joo YE, Jung YD, Yang SY, Ahn BW

This study was designed to evaluate the efficacy of an orally administered aqueous extract of glutinous rice (GRE) to protect against acute gastric mucosal lesions induced by ethanol, indomethacin, and...
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Allergenic potential and enzymatic resistance of buckwheat

Lee S, Han Y, Do JR, Oh S

  • KMID: 2313642
  • Nutr Res Pract.
  • 2013 Feb;7(1):3-8.
Buckwheat is known as a health food but is one of the major food allergens triggering potentially fatal anaphylaxis in Asia, especially in Japan and Korea. This study was conducted...
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Analysis of Low Molecular Weight Proteome from H. pylori Cell Extract Using the High Performance Liquid Chromatography

Park JW, Lee KJ, Kim KM, Joo JS, Kwon YC, Youn HS, Song JY, Kang HL, Lee KH, Baik SC, Lee WK, Cho MJ, Rhee KH

Low molecular proteins (LMPs) which are smaller than 20 kDa are difficult to visible on a standard two-dimensional SDS-polyacrylamide gel electrophoresis (2-D SDS-PAGE) map. LMPs must be enriched appropriately to...
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Pharmacological Therapy in Patients with Bleeding Peptic Ulcers

Kim JI

  • KMID: 2304764
  • Korean J Gastrointest Endosc.
  • 2009 May;38(5):247-253.
The aim of pharmacological therapy in peptic ulcer disease is to increase the intragastric pH level above 6. The use of a proton pump inhibitor (PPI), a powerful gastric acid...
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A Benign Ulcer of the Gastric Fundus Reminiscent of a Malignant Submucosal Tumor

Jung YH, Kim BW, Kim HG, Chang HJ, Song DS, Huh M, Kim MK, Jung HJ, Ji JS, Jang JW, Choi H, Choi KY, Jung IS

  • KMID: 2304807
  • Korean J Gastrointest Endosc.
  • 2008 Mar;36(3):150-153.
The gastric fundus is a rare site for benign ulcer occurrence as it consists of parietal cells, which secret gastric acid. It is resistant to gastric acid and pepsin, and...
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The Effect of Secretin on Pepsin Secretion in Heidenhain Pouch

Lee SH, Kim CB

  • KMID: 2096305
  • J Korean Surg Soc.
  • 2006 Mar;70(3):161-169.
PURPOSE: This research was done to confirm the effect of secretin on pepsin secretion and to study whether or not feeding can depress the secretin-stimulated pepsin secretion (SSPS) with its...
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Proximal Jejunal Perforation due to Postgastrectomy Bezoar

Moon HG, Jeong CY, Joo YT, Jung EJ, Lee YJ, Hong SC, Choi SK, Ha WS, Park ST

  • KMID: 1844424
  • J Korean Surg Soc.
  • 2005 Jun;68(6):509-512.
Bezoars are conglomerates of vegetable fiber and hair, or concretions of various substances located in the stomach or the intestinal tract. They are classified as phytobezoar, trichobezoar, trichophytobezoar, and concretion....
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Improvement of Pregnancy Rate in Preimplantation Genetic Diagnosis with FISH Procedure by the Laboratory Optimization and Experiences

Lim CK, Min DM, Lee HS, Byun HK, Park SY, Ryu HM, Kim JY, Koong MK, Kang IS, Jun JH

  • KMID: 1891198
  • Korean J Fertil Steril.
  • 2004 Mar;31(1):29-39.
OBJECTIVES: This study was performed to evaluate the laboratory system for successful PGD using fluorescence in situ hybridization (FISH) and the clinical outcome of PGD cycles in five years experiences. METHODS:...
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Viability of Clonorchis sinensis Metacercaria according to the Food-processing Methods

Cho YJ, Chu JP, Rim HJ, Hwang SK

  • KMID: 2082959
  • Korean J Infect Dis.
  • 2002 Aug;34(4):242-247.
BACKGROUND: Endemic areas of Clonorchis sinensis are in Asia including Korea, China, Taiwan and Vietnam. Its metacercariae consumed in uncooked, or undercooked, unfrozen fish can present human a hazard. Purposes...
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Comparison of Genetically Modified Soybean and Wild Soybean in Physicochemical Aspects

Yum HY, Lee KE, Shon MH, Kim CH, Kim KE

  • KMID: 1994340
  • Pediatr Allergy Respir Dis.
  • 2002 Mar;12(1):27-35.
PURPOSE: The list of genetically engineered crops is growing. Traits introduced into these crops include insect protection, delayed ripening, virus resistance, modified nutritional composition, herbicide tolerance etc. Most traits introduced...
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Small Intestinal(gastro)esophageal Reflux in Different Types of Gastrectomy : 24 Hour Esophageal Bilirubin Monitoring

Bhang CS, Choi MG, Kim JI, Han SW, Chung IS, Sun HS, Park DH, Won YS, Lee YB, Park WB

  • KMID: 2304656
  • Korean J Gastroenterol.
  • 1999 Feb;33(2):153-161.
BACKGROUND/AIMS: Acid and pepsin is well known to induce esophageal mucosal injury, but the role of small intestinal(gastro)esophageal reflux in causing esophageal mucosal injury is unclear. In the patients who...
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Expression of Osteopontin in Osteoclast

Chang JS, Park JH, Park YG, Kim JH

  • KMID: 2199160
  • J Korean Orthop Res Soc.
  • 1999 Oct;2(2):132-138.
PURPOSE: This study was aimed to determine the relationship between osteopontin(OPN) and osteoclast, especially focused on whether ostecolast could produce osteopontin or not. MATERIALS AND METHODS: Osteoclasts were isolated from the...
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Biochemical Analysis of the Changes of Collagen Types following Bladder Outlet Obstruction in the Rat

Kim KM, Jung JY, Kim DK, Cheong HI

  • KMID: 2290148
  • Korean J Urol.
  • 1998 Aug;39(8):723-728.
PURPOSE: We observed the ratio of collagen type III to type I by biochemical analysis in the adult rat bladder with chronic partial bladder outlet obstruction. MATERIALS AND METHODS:...
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Chromosomal instability in oral premalignancy

Kim JS, Kim HJ

  • KMID: 2306362
  • Korean J Med.
  • 1998 Jun;54(6):745-754.
BACKGROUND: Squamous cell carcinoma of the oral cavity was thought to develop through a multistep process driven by genetic changes. Recently, the use of in situ hybridization on paraffin sections...
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Experimental Studies of Gastric Physiologic Changes Following Peptic Ulcer Surgery

Lee HJ

  • KMID: 2095211
  • J Korean Surg Soc.
  • 1997 Apr;52(4):486-501.
Gastric peptic ulcer operation is designed to reduce gastric secretion, of gastric acid and pepsin enough to control the peptic ulcer diathesis and also to have least complications after operation...
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