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Penile Erection Induced by Scoparone from Artemisia capillaris through the Nitric Oxide-Cyclic Guanosine Monophosphate Signaling Pathway

Choi BR, Kim HK, Park JK

PURPOSE: The objective of this study was to evaluate the relaxant effect of scoparone from Artemisia capillaris on rabbit penile corpus cavernosum smooth muscle (PCCSM) and to elucidate the mechanism...
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A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Therapeutic Confirmatory Study to Evaluate the Safety and Efficacy of Avanafil in Korean Patients with Erectile Dysfunction

Park HJ, Kim SW, Kim JJ, Lee SW, Paick JS, Ahn TY, Park K, Park JK, Park NC

A multi-center, randomized, double-blind, placebo-controlled study was conducted with 158 subjects who were randomized to placebo or avanafil 50, 100, and 200 mg on demand for 8 weeks to evaluate...
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The Effect of Alcohol Administration on the Corpus Cavernosum

Choi SM, Seo DH, Lee SW, Lee C, Jeh SU, Kam SC, Hwa JS, Chung KH, Hyun JS

PURPOSE: We studied the effects of alcohol administration on the corpus cavernosum (CC) using an animal model. MATERIALS AND METHODS: CC sections and the aortic ring of rabbits were used in...
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Two Cases of Sleep-Related Painful Erection

Cho KH, Kim HI, Heo K, Cho YJ

Sleep-related painful erection (SRPE) is characterized by deep penile pain accompanied with erection occurring rapid eye movement (REM) movement period. Two (47-year-old and 40-year-old, respectively) male visited with the complaint...
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Gene expression profile comparison in the penile tissue of diabetes and cavernous nerve injury-induced erectile dysfunction rat model

Kam SC, Lee SH, Jeon JH, So I, Chae MR, Park JK, Lee SW

PURPOSE: To investigate the effects of cavernous nerve injury (CNI) on gene expression profiles in the cavernosal tissue of a CNI-induced erectile dysfunction (ED) model and to provide a basis...
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Effects of Omega-3 Fatty Acids on Erectile Dysfunction in a Rat Model of Atherosclerosis-induced Chronic Pelvic Ischemia

Shim JS, Kim DH, Bae JH, Moon DG

The aim of this study was to investigate whether the omega-3 fatty acids help to improve erectile function in an atherosclerosis-induced erectile dysfunction rat model. A total of 20 male...
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Clinical Management of Priapism: A Review

Shigehara , Namiki M

Priapism is defined as a persistent and painful erection lasting longer than four hours without sexual stimulation. Based on episode history and pathophysiology, priapism is classified into three subtypes: ischemic...
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Optimizing in vivo gene transfer into mouse corpus cavernosum by use of surface electroporation

Song KM, Choi MJ, Kwon MH, Ghatak K, Park SH, Ryu DS, Ryu JK, Suh JK

PURPOSE: Electroporation is known to enhance the efficiency of gene transfer through a transient increase in cell membrane permeability. The aim of this study was to determine the optimal conditions...
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Efficacy of Long-Term Daily Dosage of Alfuzosin 10 mg upon Sexual Function of Benign Prostatic Hypertrophy Patients: Two-Year Prospective Observational Study

Yoon S, Choi JH, Lee SH, Choi SM, Jeh SU, Kam SC, Hwa JS, Chung KH, Hyun JS

PURPOSE: To identify sexual function improvement associated with alfuzosin (10 mg daily for 2 years). MATERIALS AND METHODS: We enrolled 30 men with lower urinary tract symptom (LUTS) who visited Gyeongsang...
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Prophylactic Phenylephrine for Iatrogenic Priapism: A Pilot Study With Peyronie's Patients

Jiang P, Christakos A, Fam M, Sadeghi-Nejad H

PURPOSE: Although penile duplex Doppler ultrasonography (PDDU) is a common and integral procedure in a Peyronie's disease workup, the intracavernosal injection of vasoactive agents can carry a serious risk of...
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Clinical Neuroanatomy and Neurotransmitter-Mediated Regulation of Penile Erection

Jung J, Jo HW, Kwon H, Jeong NY

  • KMID: 2232925
  • Int Neurourol J.
  • 2014 Jun;18(2):58-62.
Erectile dysfunction (ED) has an adverse impact on men's quality of life. Penile erection, which is regulated by nerves that are innervated into the erectile tissue, can be affected by...
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A Case Report of Priapism Caused by Ziprasidon

Karamustafalioglu N, Kalelioglu T, Tanriover , Gungor FC, Genc A, Ilnem C

  • KMID: 2316322
  • Psychiatry Investig.
  • 2013 Dec;10(4):425-427.
Priapism is defined as having prolonged (more than 6 h), and usually painful penile erection that occurs without a sexual desire or arousal. Only a very few priapism cases caused...
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Priapism: Current Updates in Clinical Management

Song PH, Moon KH

  • KMID: 2315936
  • Korean J Urol.
  • 2013 Dec;54(12):816-823.
Priapism is a persistent penile erection that continues for hours beyond, or is unrelated to, sexual stimulation. Priapism requires a prompt evaluation and usually requires an emergency management. There are...
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Transient Distal Penile Corporoglanular Shunt as an Adjunct to Aspiration and Irrigation Procedures in the Treatment of Early Ischemic Priapism

Canguven O, Cetinel C, Horuz R, Tarhan F, Hamarat B, Goktas C

  • KMID: 2316018
  • Korean J Urol.
  • 2013 Jun;54(6):394-398.
PURPOSE: Ischemic priapism, a compartment syndrome, requires urgent treatment in order to nourish the corpora cavernosa. As the first step, aspiration of blood and irrigation of the cavernosal bodies is...
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Effects and Mechanism of Action of a Tribulus terrestris Extract on Penile Erection

Do J, Choi S, Choi J, Hyun JS

  • KMID: 2430620
  • Korean J Urol.
  • 2013 Mar;54(3):183-188.
PURPOSE: Tribulus terrestris has been used as an aphrodisiac. However, little is known about the effects and mechanism of action of T. terrestris on penile erection. Therefore, the effect of...
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Prostate Cancer and Sexual Function

Hyun JS

  • KMID: 2320882
  • World J Mens Health.
  • 2012 Aug;30(2):99-107.
Prostate cancer is now ranked fifth in incidence among cancers in Korean adult males. This is attributable to the more Westernized dietary style which increases the morbidity of prostate cancer...
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Therapeutic Angiogenesis as a Potential Future Treatment Strategy for Erectile Dysfunction

Ryu JK, Suh JK

  • KMID: 2320881
  • World J Mens Health.
  • 2012 Aug;30(2):93-98.
The cavernous endothelium plays a crucial role in regulating the tone of the underlying smooth muscle and physiologic penile erection. Recently, the link between erectile dysfunction (ED) and cardiovascular disease...
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Isolation and Characterization of Smooth Muscle Cells from Rat Corpus Cavernosum Tissue for the Study of Erectile Dysfunction

Chung H, Jung SH, Ryu JK, Kim B, Kim HS, Yang SK

  • KMID: 2315598
  • Korean J Urol.
  • 2012 Aug;53(8):556-563.
PURPOSE: Primary culture of the cavernous smooth muscle cells from corpus cavernous tissues is known to be difficult, mainly because of contamination with fibroblasts. We applied a new method for...
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The Effects of New Herbal Formula (KBMSI-1) on the Penile Erection and Corpus Cavernosum in Streptozotocin-induced Diabetic Rats

Yoon BI, Shin TS, Woo JC, Kim SJ, Kim HS, Ha US, Kim HJ, Hwang SY, Kim SW

PURPOSE: The aim of this study was to investigate the effects of new herbal formula (KBMSI-1) on erectile dysfunction in streptozotocin-induced diabetic rat model. MATERIALS AND METHODS: We used male Sprague-Dawley...
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The Effect of Cyanidin-3-O-beta-d-glucopyranoside on the Penile Erection and Corpus Cavernosum in a Rat Model of Diabetic Erectile Dysfunction

Ha US, Koh JS, Woo JC, Kim SJ, Kim SJ, Jang H, Yoon BI, Hwang SY, Kim SW

PURPOSE: The aim of this study was to evaluate Cyanidin-3-O-beta-d-glucopyranoside on improvement and protection for erectile function. MATERIALS AND METHODS: Sprague-Dawley rats (12wks old) were divided into three groups (n=12 in...
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