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Brain Factor-7® improves learning and memory deficits and attenuates ischemic brain damage by reduction of ROS generation in stroke in vivo and in vitro

Noh Y, Lee JW, Hong J, Kim SS, Ahn JH, Lee TK, Kim B, Won MH

Brain Factor-7® (BF-7), silk fibroin peptide, is known to be effective in improvement of memory and learning ability. In this study, the effects of BF-7 (10 mg/kg, p.o., pre-treatment for 7 days...
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Bile duct ligation of C57BL/6 mice as a model of hepatic encephalopathy

Cho I, Koo BN, Kam EH, Lee SK, Oh H, Kim SY

Background: Bile duct ligation (BDL) has been used for experimental research on hepatic encephalopathy (HE) caused by chronic liver disease. However, little research has been done on a BDL model...
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Transient forebrain ischemia induces impairment in cognitive performance prior to extensive neuronal cell death in Mongolian gerbil (Meriones unguiculatus)

Kondo T, Yoshida S, Nagai H, Takeshita , Mino M, Morioka H, Nakajima T, Kusakabe K, Okada T

In Mongolian gerbils, bilateral common carotid artery occlusion (BCCAO) for several minutes induces ischemia, due to an incomplete circle of Willis, resulting in delayed neuronal cell death in the Cornet...
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HPLC analysis of Phenolic Substances and Anti-Alzheimer's Activity of Korean Quercus Species

Nugroho A, Song BM, Seong SH, Choi JS, Choi J, Choi JY, Park HJ

This study aimed to establish the quantitative method to analyze the content of peroxynitrite-scavengers belonging to polyphenols in six Korean Quercus species (Quercus mongolica, Q. dentata, Q. acutissima, Q. alienta,...
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Effect of Codonopsis lanceolata with Steamed and Fermented Process on Scopolamine-Induced Memory Impairment in Mice

Weon JB, Yun BR, Lee J, Eom MR, Ko HJ, Kim JS, Lee HY, Park DS, Chung HC, Chung JY, Ma CJ

  • KMID: 2048312
  • Biomol Ther.
  • 2013 Sep;21(5):405-410.
Codonopsis lanceolata (Campanulaceae) traditionally have been used as a tonic and to treat patients with lung abscesses. Recently, it was proposed that the extract and some compounds isolated from C....
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Effects of Streptozotocin-Induced Type 1 Diabetes on Cell Proliferation and Neuronal Differentiation in the Dentate Gyrus; Correlation with Memory Impairment

Choi JH, Hwang IK, Yi SS, Yoo KY, Lee CH, Shin HC, Yoon YS, Won MH

  • KMID: 1472506
  • Korean J Anat.
  • 2009 Mar;42(1):41-48.
We examined the effects of steptozotocin (STZ)-induced type 1 diabetes on cell proliferation and neuroblasts in the subgranular zone of the hippocampal dentate gyrus (SZDG) of male Wistar rats. Change...
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