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DWN12088, A Prolyl-tRNA Synthetase Inhibitor, Alleviates Hepatic Injury in Nonalcoholic Steatohepatitis

Lee DK, Jo SH, Lee ES, Ha KB, Park NW, Kong DH, Park SI, Park JS, Chung CH

Background: Nonalcoholic steatohepatitis (NASH) is a liver disease caused by obesity that leads to hepatic lipoapoptosis, resulting in fibrosis and cirrhosis. However, the mechanism underlying NASH is largely unknown, and...
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Multimodal Imaging Assessment of Typical Sympathetic Ophthalmia: A Case Report

Park SI, Park SH, Kim BJ, Lee WH, Han YS

Purpose: Despite the relatively low incidence of sympathetic ophthalmia, prompt diagnosis is essential to prevent visual impairment in both eyes. Here, we present a case of sympathetic ophthalmia, emphasizing distinctive...
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A Case of Bilateral Trigeminal Amyloidoma Diagnosed Through an Endoscopic Transsphenoidal Approach

Park SI, Ryu G

Amyloidosis is a systemic disease characterized by the accumulation of amyloid protein in multiple organs. Amyloidoma, in contrast, is an uncommon localized form of amyloidosis that presents as a single...
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Flow Diverter Treatment Using a Flow Re-Direction Endoluminal Device for Unruptured Intracranial Vertebral Artery Dissecting Aneurysm: Single-Center Case Series and Technical Considerations

Suh DC, Song Y, Park SI, Kwon B

Purpose: This study aimed to evaluate the effectiveness, safety, and technical considerations of flow diverter (FD) treatment using a Flow Re-direction Endoluminal Device (FRED) for unruptured intracranial vertebral artery dissecting...
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Long-term Outcome of Anterior Chamber Parameters after Laser Iridotomy and Iridoplasty in Primary Angle Closure Glaucoma

Park SI, Lee WH, Kang TS, Kim JH, Han YS, Cho HK

Purpose: To investigate the long-term outcomes of anterior chamber angle parameters in patients with primary angle closure glaucoma (PACG) after peripheral laser iridotomy (LI) combined with iridoplasty (PI) using a...
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Addendum: Outpatient Day-Care Management of Unruptured Intracranial Aneurysm: A Retrospective Cohort Study

Suh DC, Choi YH, Park SI, Yun S, Jeong SY, Jeong S, Kwon B, Song Y

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One-Unit Osteotomy to Correct Deviated Bony Dorsum

Kim BK, Heo Y, Park SI, Hong SD, Jung YG, Kim HY

Objectives. A crooked nose is frequently caused by nasal bony vault deviation, and proper management of the bony vault is an integral part of rhinoplasty. Conventional osteotomy to correct a...
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Long-term Surgical Outcomes in Oligometastatic Non-small Cell Lung Cancer: A Single-Center Study

Yoo S, Cho WC, Lee GD, Choi S, Kim HR, Kim YH, Kim DK, Park SI, Yun JK

Background: We reviewed the clinical outcomes of patients with oligometastatic (OM) non-small cell lung cancer (NSCLC) who received multimodal therapy including lung surgery. Methods: We retrospectively analyzed 117 patients with OM...
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The Role of Adjuvant Therapy Following Surgical Resection of Small Cell Lung Cancer: A Multi-Center Study

Park SY, Park S, Lee GD, Kim HK, Choi S, Kim HR, Kim YH, Kim DK, Park SI, Hong TH, Choi YS, Kim J, Cho JH, Shim YM, Zo JI, Na KJ, Park IK, Kang CH, Kim YT, Park BJ, Lee CY, Lee JG, Kim DJ, Paik HC

Purpose This multi-center, retrospective study was conducted to evaluate the long-term survival in patients who underwent surgical resection for small cell lung cancer (SCLC) and to identify the benefit of...
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Network Structure of Depressive Symptoms in General Population

Park Si, Lee KK, Lee SB, Lee JJ, Kim KM, Jeong HS, Kim D

Objectives:Although subclinical depression symptoms are associated with suicidal idea, most research have focused on clinical depression such as major depressive disorder or dysthymia. The aim of this study is to...
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Bridging to lung transplantation in idiopathic pulmonary fibrosis

Kim G, Oh DK, Shim TS, Kim DK, Choi S, Lee GD, Kim W, Park SI, Hong SB

Background: Among interstitial lung diseases (ILD), idiopathic pulmonary fibrosis (IPF) and connective tissue diseases (CTD) have different characteristics and prognosis; IPF is associated with older age and poor prognosis. Donor...
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Therapeutic Effect of Multilevel Surgery on Laryngopharyngeal Reflux in Obstructive Sleep Apnea Patients: Impact on the Reflux Symptom Index and Reflux Finding Score

Song B, Jung YG, Hong SD, Lee EK, Kim BK, Park SI, Jung SH, Ryu G, Kim HY

Objectives. Our previous study found that multilevel obstructive sleep apnea (OSA) surgery mitigated laryngopharyngeal reflux (LPR) symptoms in terms of the reflux symptom index (RSI), but no studies have investigated...
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Incorporation of real-world data to a clinical trial: use of external controls

Kim TE, Park SI, Shin KH

As real-world data (RWD) becomes more available and the methodology for handling RWD evolves, the use of RWD in drug development and drug approval is drawing interest. One of the...
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Successful Bilateral Re-Stenting of Re-Stenosis after Carotid Artery Stenting in a Patient with Radiation-Induced Carotid Stenosis

Kim Tw, Kim EJ, Woo HG, Park Si, Ha SH, Heo SH

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Outpatient Day-Care Management of Unruptured Intracranial Aneurysm: A Retrospective Cohort Study

Suh DC, Choi YH, Park SI, Yun S, Jeong SY, Jeong S, Kwon B, Song Y

Objective: This study aimed to assess the outcomes of outpatient day-care management of unruptured intracranial aneurysm (UIA), and to present the risks associated with different management strategies by comparing the...
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Clinical Manifestation and Radiologic Patterns of Spontaneous Cervicocephalic Dissection According to the Anatomic Location: A Single-Center Analysis in Korean Patients

Song Y, Park SI, Budianto P, Kwon B, Suh DC

Purpose: Spontaneous cervicocephalic dissection (SCAD) is an important cause of stroke and shows various lesion locations and clinical features. The purpose of this study was to analyze the location of...
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An Overview of Surgical Treatment of Thymic Epithelial Tumors in Korea: A Retrospective Multicenter Analysis

Lee JO, Lee GD, Kim HR, Kim DK, Park SI, Cho JH, Kim HK, Choi YS, Kim J, Shim YM, Park S, Park IK, Kang CH, Kim YT, Park SY, Lee CY, Lee JG, Kim DJ, Paik HC, for the Korean Association for Research on the Thymus

Background: Thymic epithelial tumors (TETs) are rare, and information regarding their surgical outcomes and prognostic factors has rapidly changed in the past few decades. We analyzed surgical treatment practices for TETs...
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Predicting Postoperative Complications and Long-Term Survival After Lung Cancer Surgery Using Eurolung Risk Score

Yun JK, Jeong JH, Lee GD, Kim HR, Kim YH, Kim DK, Park SI, Choi S

Background: This study aimed to assess the clinical relevance of the parsimonious Eurolung risk scoring system for predicting postoperative morbidity, mortality, and long-term survival in Korean patients with surgically resected...
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Natural Progression of Ground-glass Nodules after Curative Resection for Non-small Cell Lung Cancer

Lee K, Kim HR, Park SI, Kim DK, Kim YH, Choi S, Lee GD

Background: This retrospective study investigated the natural course of synchronous groundglass nodules (GGNs) that remained after curative resection for non-small-cell lung cancer (NSCLC). Methods: Prospectively collected retrospective data were reviewed concerning...
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Long-term Outcomes and Factors Affecting the Survival of Patients with Mucosal Esophageal Squamous Cell Carcinoma

Kim GH, Na HK, Ahn JY, Lee JH, Jung KW, Kim DH, Kim HR, Choi KD, Song HJ, Kim YH, Lee GH, Jung HY, Park SI

Background/Aims: Data regarding the prognosis of early esophageal cancer are lacking. This study investigated the long-term outcomes and factors affecting the survival of patients with mucosal esophageal squamous cell carcinoma...
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