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Altered Metabolic Phenotypes and Hypothalamic Neuronal Activity Triggered by Sodium-Glucose Cotransporter 2 Inhibition

Lee HG, Jung IH, Park BS, Yang HR, Kim KK, Tu TH, Yeh JY, Lee S, Yang S, Lee BJ, Kim JG, Nam-Goong IS

Background: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are currently used to treat patients with diabetes. Previous studies have demonstrated that treatment with SGLT-2 inhibitors is accompanied by altered metabolic phenotypes. However,...
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Pharmacological treatment of Ménière disease

Park BS, Kang BH, Suh MJ

Background: Despite significant progress in audiology, there is no definitive treatment option for Ménière disease due to its multifactorial etiology. Current Concepts: The primary treatment goal for Ménière disease is first,...
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Ovastacin: An oolemma protein that cleaves the zona pellucida to prevent polyspermy

Kang I, Koo M, Yoon H, Park BS, Jun JH, Lee J

Monospermy occurs in the process of normal fertilization where a single sperm fuses with the egg, resulting in the formation of a diploid zygote. During the process of fertilization, the...
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Crowned dens syndrome as a rare cause of anterior neck pain after transurethral resection of the prostate: a case report

Jeong MG, Park BS, Son ES, Cho JH

We describe the case of a 79-year-old man who presented with progressive aggravation of severe axial neck pain and fever 3 days after transurethral resection of the prostate (TURP), despite...
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Mixture of Corni Fructus and Schisandrae Fructus improves testosterone-induced benign prostatic hyperplasia through regulating 5α-reductase 2 and androgen receptor

Hwangbo H, Kim MY, Ji SY, Park BS, Kim T, Yoon S, Kim H, Kim SY, Jung H, Kim T, Lee H, Kim GY, Choi YH

BACKGROUND/OBJECTIVES: Benign prostatic hyperplasia (BPH) characterized by an enlarged prostate gland is common in elderly men. Corni Fructus (CF) and Schisandrae Fructus (SF) are known to have various pharmacological effects,...
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Microvascular flow imaging to differentiate focal hepatic lesions: the spoke-wheel pattern as a specific sign of focal nodular hyperplasia

Rónaszéki AD, Dudás I, Zsély B, Budai BK, Stollmayer R, Hahn O, Csongrády B, Park Bs, Maurovich-Horvat P, Győri G, Kaposi PN

Microvascular flow imaging (MVFI) is an advanced Doppler ultrasound technique designed to detect slow-velocity blood flow in small-caliber microvessels. This technique is capable of realtime, highly detailed visualization of tumor...
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Comparison of kidney transplant outcomes before and after COVID-19 pandemic: a single-institution experience

Lee YJ, Park BS, Park S, Kim YW

COVID-19 pandemic had a significant impact on the field of kidney transplantation. Recipient was found to have high mortal-ity associated with COVID-19 infection and also had vaccination-related problems. We conducted...
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Gastric inflammatory change due to infected pancreatic pseudocyst mimicking malignant gastroepithelial tumor

Park BS, Kim SJ, Chung JH, Kim TU

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Multidisciplinary treatment strategy for early colon cancer

Son GM, Park SB, Kim TU, Park BS, Lee IY, Na JY, Shin DH, Oh SB, Cho SH, Kim HS, Kim HW

Background: Treatment for early colon cancer has progressed rapidly with endoscopic resection and minimally invasive surgery. Selection of patients without risk of lymph node metastasis is necessary before deciding on...
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Clinical significance of copeptin as an early predictor of renal graft dysfunction in renal transplant recipients

Lee YJ, Heo CM, Park S, Kim IH, Park JH, Ko J, Park BS, Kim YW

Background: Copeptin is the carboxyl-terminal part of the vasopressin precursor protein, and its concentration is an independent predictor of the onset of chronic kidney disease and a rapid decline in...
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Comparison of Stent-Assisted Coil Embolization Versus Coil Embolization Alone for Ruptured Cerebral Aneurysms with Mild Symptoms: A Single-Clinic Experience

Lim G, Shin SH, Lee TY, Kwon WJ, Park BS, Kwon SC

Purpose To evaluate the safety and efficacy of stent-assisted coil embolization (SAC) in acutely ruptured cerebral aneurysms without severe symptoms, and thus, the usefulness of the stent itself in patients...
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Multidisciplinary treatment strategy for early rectal cancer

Son GM, Lee IY, Cho SH, Park BS, Kim HS, Park SB, Kim HW, Oh SB, Kim TU, Shin DH

The early rectal cancer (ERC) has increased with the national cancer screening project for early detection of colorectal cancer. The gold standard treatment for low rectal cancer is low anterior...
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Exercise-induced rhabdomyolysis with acute kidney injury complicated by posterior reversible encephalopathy syndrome: a case report

Kim SM, Lee YJ, Heo CM, Park SH, Park KM, Ko JH, Park BS, Kim YW

Posterior reversible encephalopathy syndrome (PRES) is a rare condition manifested by inflammation in certain areas of the brain. Rhabdomyolysis with acute kidney injury (AKI) complicated by PRES is rarely reported....
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Decorin: a multifunctional proteoglycan involved in oocyte maturation and trophoblast migration

Park BS, Lee J, Jun JH

Decorin (DCN) is a proteoglycan belonging to the small leucine-rich proteoglycan family. It is composed of a protein core containing leucine repeats with a glycosaminoglycan chain consisting of either chondroitin...
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Synchronous Quadruple Colon Cancer With Two Lesions Previously Obscured by Ischemic Colitis, Plus Bladder Cancer and Thymoma: A Case Report

Park BS, Cho SH, Kim SJ, Kim TU, Kim DI, Son GM, Kim HS

Synchronous quadruple colorectal cancer (CRC) is extremely rare without genetic alterations. We present a case of synchronous quadruple CRC with 2 lesions previously obscured by ischemic colitis. A 73-year-old woman...
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Tumor grade 2 as the independent predictor for lymph node metastasis in 10–20 mm sized rectal neuroendocrine tumor

Park BS, Cho SH, Son GM, Kim HS, Kim SJ, Park SB, Choi CW, Kim HW, Shin DH

Purpose: Rectal neuroendocrine tumors (NETs)
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Endoscopic Features of Submucosal Invasion in Undifferentiated-type Early Gastric Cancer Less than 20 mm in Size without Ulceration

Kim SJ, Park BS, Choi CW, Kim HW, Kang DH, Park SB

Background/Aims: The prediction of invasion depth is important to decide the treatment modality for undifferentiated-type early gastric cancer (EGC) less than 20 mm in size without ulceration. We aimed to...
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The effects of direct hemoperfusion with polymyxin B-immobilized fiber in patients with acute exacerbation of interstitial lung disease

Lee JH, Park JH, Kim HJ, Kim HK, Jang JH, Kim YK, Park BS, Park SH, Kim IH, Kim SH, Heo W, Jang HJ

Background: Acute exacerbation of interstitial lung disease (AE-ILD) causes clinically significant deterioration and has an extremely poor prognosis with high mortality. Recently, several studies reported the effectiveness of direct hemoperfusion...
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Analysis of the risk factors of acute kidney injury after total hip or knee replacement surgery

Lee YJ, Park BS, Park S, Park JH, Kim IH, Ko J, Kim YW

Background: Postoperative acute kidney injury (AKI), which increases the risk of postoperative morbidity and mortality, poses a major concern to surgeons. We conducted this study to analyze the risk factors...
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Autophagy inhibition by cudraxanthone D regulates epithelial–mesenchymal transition in SCC25 cells

Yu SB, Bang TH, Kang HM, Park BS, Kim IR

Cudraxanthone D (CD) is a natural xanthone compound derived from the root barks of Cudrania tricuspidata . However, the biological functions of CD in human metabolism have been rarely reported...
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