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Diagnostic Approach to the Suspected Cases of Hereditary Spastic Paraplegia

Choi SJ, Sung JJ

Hereditary spastic paraplegia (HSP) is a heterogeneous group of monogenic neurodegenerative disorders characterized by progressive spasticity of the lower limbs. The clinical features and imaging abnormalities vary greatly according to...
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Whole Lumbar Spinal Subdural Hematoma with Progressive Paraplegia after Lumbar Spinal Epidural Injection

Choi BW, Park KG

Spinal hematomas are a rare but serious complication that is typically observed in the epidural space. Spinal subdural hematomas are a dangerous clinical situation because of their potential to cause...
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Pediatric tetrasomy 18p presenting as a spastic cerebral palsy: A case report

Lim I, Park SH, Suh MR, Kwak H, Park W, Shim SH, Kim M

Tetrasomy 18p is a genetic syndrome caused by an isochromosome consisting of two copies of the short arm of chromosome 18. Clinically, pediatric cases of tetrasomy 18p manifest with global...
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Paraplegia after transforaminal epidural steroid injection in a patient with severe lumbar disc herniation - A case report -

Jeon SH, Jang W, Kim SH, Cho YH, Lee HS, Ko HC

Background: Transforaminal epidural steroid injection (TFESI) is a conservative treatment for patients with lumbar disc herniation (LDH). However, there are reports of various complications that can occur after TFESI; among...
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Paraplegia after Open Repair of Suprarenal Abdominal Aortic Aneurysm

Kim HJ, Park HS, Shin CS, Cho JS, Lee T

Spinal cord ischemia after open repair of abdominal aortic aneurysm (AAA) is an unpredictable and devastating complication. We present a case report of a patient who developed paraplegia 6 hours...
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SPG11 Mutation in Hereditary Spastic Paraplegia with Thin Corpus Callosum Diagnosed by Targeted Gene Panel Sequencing

Kim H, Min YG, Hong SB, Kim MJ, Seong MW, Shin JY

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Hereditary spastic paraplegia with thin corpus callosum due to novel homozygous mutation in SPG11 gene

Kang SY, Kim JG, Oh JH

The most common form of autosomal recessive hereditary spastic paraplegia (HSP) is caused by mutations in SPG11/KIAA1840 gene, which encodes for spatacsin. The clinical presentation of SPG11 is characterized by...
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Glial Cell Line-derived Neurotrophic Factor-overexpressing Human Neural Stem/Progenitor Cells Enhance Therapeutic Efficiency in Rat with Traumatic Spinal Cord Injury

Hwang K, Jung K, Kim IS, Kim M, Han J, Lim J, Shin JE, Jang JH, Park KI

Spinal cord injury (SCI) causes axonal damage and demyelination, neural cell death, and comprehensive tissue loss, resulting in devastating neurological dysfunction. Neural stem/progenitor cell (NSPCs) transplantation provides therapeutic benefits for...
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Paraplegia after celiac plexus neurolysis in a patient with pancreatic cancer: A case report and literature review

Kim SH, Jang KH, Cheon BK, Lim JA, Woo NS, Kim HK, Kim JH

A 65-year-old male patient underwent C-arm fluoroscopy-guided bilateral celiac plexus neurolysis to relieve peritoneal seeding-related pain associated with pancreatic cancer. Following confirmation of spreading, and no intravascular injection of contrast...
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Spinal Cord Infarction Following Total Hysterectomy Due to Severe Postpartum Hemorrhage

Kim SR, Park JW, Kim JS

Spinal cord infarction (SCI) is a rare but often disastrous disorder caused by various pathologic status. The research reports a 34-year-old woman developed SCI after spinal anesthesia for relieving labor...
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Changes in Diffusion Metrics of the Red Nucleus in Chronic Stroke Patients With Severe Corticospinal Tract Injury: A Preliminary Study

Kim H, Lee H, Jung KI, Ohn SH, Yoo WK

OBJECTIVE: To explore plastic changes in the red nucleus (RN) of stroke patients with severe corticospinal tract (CST) injury as a compensatory mechanism for recovery of hand function. METHODS: The moderate...
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Paraplegia Following Spinal Cord Contusion from an Indirect Gunshot Injury

Khan K, Dieudonne , Saeed S, Alothman S, Saeed Y, Gray S

Spinal cord injuries are debilitating and life threatening. Paraplegia due to direct traumatic gunshot injury to the spinal cord is common. The most common cause of spinal cord injury is...
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Transient paraplegia after neurolytic splanchnic block in a patient with metastatic colon carcinoma

Oguz G, Senel G, Kocak N

We present a patient with metastatic colon carcinoma who developed paraplegia following a neurolytic splanchnic block. A 41-year old man with metastatic adenocarcinoma of the colon received a splanchnic neurolytic...
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Treatment of Spinal Infection Following Bilateral Total Knee Replacement Postoperative Infection

Shim BJ, Sohn OJ, Cho CW

Postoperative infection from total knee arthroplasty (TKA) is an issue drawing great attention, which can manifest as a local or general infection. Its development into sepsis has also occasionally been...
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Paraplegia in an Ankylosing Spondylitis Patient with a Neglected Spine Fracture after Osteosynthesis for Fracture of the Femur: A Case Report

You JW, Kang SW, Sohn HM

STUDY DESIGN: Case report. OBJECTIVES: To report a case of paraplegia in a patient with thoracic kyphosis after osteosynthesis for a fracture of the femur. SUMMARY OF LITERATURE REVIEW: There are few...
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Sudden Paraplegia Caused by Nontraumatic Cervical Disc Rupture: A Case Report

Kim SM, Choi BS, Lee S

A 38-year-old man visited our Emergency Department for sudden onset paraplegia that occurred 1 hour ago. He felt a piercing pain in the posterior neck and became paraplegic while he...
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Demographic Trends of Patients with Compressive Myelopathy in a Developing Asian Country

Kumar V, Kumar A, Dhatt SS, Bahadur R

STUDY DESIGN: Prospective case series. PURPOSE: To analyze the demographic picture of the patients suffering from compression myelopathy due to various spinal problems. Overview of Literature: There is a lack of...
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Acute Paraplegia as a Result of Hemorrhagic Spinal Ependymoma Masked by Spinal Anesthesia: Case Report and Review of Literature

Lee SH, Park DJ, Jeun SS

Ependymomas are the most common intramedullary spinal cord tumors in adults. Although a hemorrhage within spinal ependymoma on imaging studies is not uncommon, it has rarely been reported to bea...
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Paraplegia following cervical epidural catheterization using loss of resistance technique with air: a case report

Chae YJ, Han KR, Park HB, Kim C, Nam SG

We report a case of paraplegia without neurologic deficit of upper extremities following cervical epidural catheterization using air during the loss of resistance technique. A 41-year-old woman diagnosed with complex...
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Delayed Posttraumatic Spinal Epidural Hematoma: Importance of Early Surgical Treatment for Neurologic Deficits

Lee DH, Oh TH, Lee JC, Lim KH

Delayed posttraumatic spinal epidural hematoma is an extremely rare disease, and it remains a challenge for surgical teams of trauma centers. Magnetic resonance imaging is an essential tool for early...
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