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Pathological Worry is Related to Poor Long-Term Pharmacological Treatment Response in Patients With Panic Disorder

Kim HJ, Kim JE, Lee SH

Objective Several predictors of unfavorable pharmacological treatment response (PTR) in panic disorder (PD) patients have been suggested, such as the duration of the illness, presence of agoraphobia, depression, being a...
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Emergency Department Visits for Panic Attacks and Ambient Air Pollution: A Time-Stratified Case-Crossover Analysis

Moon YK, Lee W, Oh S, Kim H, Myung W, Lee H, Kim DK

Objectives This study investigates the association between short-term exposure to air pollutants and panic attacks requiring emergency department (ED) visits. Methods We identified 1926 patients who visited EDs in Seoul with...
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Clinical Characteristics in Panic Disorder Patients in Emergency Department

Lee CJ, Nam BW, Sohn IK

Objectives:This study was designed to investigate datas related to panic attack and treatment in emergency room of panic disorder patients who visited emergency room for panic attack. Methods:A retrospective analysis of...
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Functional Impairment in Patients with Panic Disorder

Kim HJ, Kim JE, Lee SH

Objective Anxiety and depression and sociodemographic factors such as age, gender, education level, income, and marital status among people with panic disorder (PD) are associated with functional impairment in the...
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Impairment of Working Memory in Patients with Panic Disorder

Chae SH, Shin YC, Shin DW, Oh KS, Jeon SW, Cho SJ

Objective : The purpose of this study was to investigate the impairment of working memory in patients with panic disorder through neuropsychological examination. Methods : A total of 38 patients who...
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The Burden of Agoraphobia in Worsening Quality of Life in a Community Survey in Italy

Preti A, Piras M, Cossu G, Pintus E, Pintus M, Kalcev G, Cabras F, Moro MF, Romano F, Balestrieri M, Caraci F, Dell’Osso L, Sciascio GD, Drago F, Hardoy MC, Roncone R, Faravelli C, Musu M, Finco G, Nardi AE, Carta MG

Objective Current nosology redefined agoraphobia as an autonomous diagnosis distinct from panic disorder. We investigated the lifetime prevalence of agoraphobia, its association with other mental disorders, and its impact on...
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Early Trauma Is Associated with Poor Pharmacological Treatment Response in Patients with Panic Disorder

Kim HJ, Kim JE, Lee SH

Objective Pharmacotherapy is established as an effective method for reducing symptoms of panic disorder (PD). However, about 20–40% of PD patients are treatment-resistant. Predictors of pharmacotherapy outcomes for PD patients...
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The Mediating Effect of Insomnia on the Relationship between Panic Symptoms and Depression in Patients with Panic Disorder

Hong S, Kim S, Park DH, Ryu SH, Ha JH, Jeon HJ

Background: This study aimed to determine if sleep disturbances may mediate the relationship between panic symptoms and depression in patients with panic disorder (PD). Methods: Electronic medical records were retrospectively reviewed...
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Association between Uncinate Fasciculus Integrity and Agoraphobia Symptoms in Female Patients with Panic Disorder

Kim SE, Bang M, Won E, Lee SH

Objective: Although neural correlates of sub-clinical agoraphobia (AG) symptoms have been previously suggested, only a few studies evaluating structural changes of the brain have been conducted in agoraphobic patients with...
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Childhood Trauma and Pharmacotherapy Retention among Outpatients with Panic Disorder

Kim DJ, Kim D, Lee J, Kim Y, Sohn S

Objectives:This study investigated lifetime experiences of trauma, treatment retention, and psychiatric symptoms among outpatients with panic disorder after initiation of pharmacotherapy. Our research hypothesis was that panic patients with childhood...
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Higher Rightward Laterality of the Hippocampal Tail and Its Association with Early Trauma in Panic Disorder

Lee J, Song Y, Won E, Bang M, Lee SH

Objective: Early trauma (ET) is widely recognized as a contributing factor to the development of panic disorder (PD) in patients. However, there is a dearth of research on the specific...
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Effects of BDNF Val66Met Polymorphism on White Matter Microalterations of the Corpus Callosum in Patients with Panic Disorder in Korean Populations

Kim HJ, Bang M, Lee KS, Choi TK, Park CI, Lee SH

Objective The brain-derived neurotrophic factor (BDNF) Val66Met (rs6265) polymorphism is suggested to be associated with the pathophysiology of anxiety disorders, including panic disorder (PD). Although the fronto-limbic white matter (WM)...
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Bidirectional Association between First-Episode Panic Disorder and Major Depressive Disorder in a Nationwide General Population Survey in Korea

Woo J, Hong JP, Cho SJ, Lee JY, Joen HJ, Kim BS, Chang SM

BACKGROUND: Panic disorder (PD) and major depressive disorder (MDD) can occur concurrently, despite different clinical manifestations. Because MDD and PD patients tend to have more complicated conditions, understanding the co-occurrence...
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Korean Guidelines for the Treatment of Panic Disorder 2018: Psychosocial Treatment Strategies

Gim M, Kim MK, Lee JH, Kim W, Moon E, Seo HJ, Koo BH, Yang JC, Lee KS, Lee SH, Kim CH, Yu BH, Suh HS

OBJECTIVE: The purpose of this study was to investigate consensus relative to treatment strategies for psychosocial treatment in panic disorder, that represents one subject addressed by the Korean guidelines for...
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The Bodily Panic Symptoms and Predisposing Stressors in Korean Patients with Panic Disorder

Lee HJ, Gim MS, Kim SJ, Park SC, Yang JC, Lee KU, Lee SH, Lee SJ, Lim SW, Chae JH, Han SW, Hong JP, Seo HJ

OBJECTIVES: The purpose of this study was to investigate the distinctive features of bodily panic symptoms and the predisposing conditions in Korean patients with panic disorder. METHODS: This was a retrospective...
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Clinical Characteristics of Female Panic Disorder Patients with Abortion History

Hwang HJ, Oh J, Bang M, Won E, Lee KS, Choi TK, Lee SH

OBJECTIVES: The objective of this study is to investigate differences in clinical characteristics between female panic disorder (PD) patients with abortion history (PD+A) and without abortion history (PD−A). METHODS: We examined...
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From the Onset of Panic Symptoms to Getting to a Psychiatric Treatment : The Change by Improved Public Awareness of Panic Disorder in Korea

Choi YW, Seo HJ, Han SW, Hong JP, Lee KU, Kim SJ, Lim SW, Lee SH, Yang JC, Lee SJ, Park SC, Gim MS, Chae JH

OBJECTIVE: This study aimed to investigate the general process from the symptom onset to the psychiatric treatment in Korean panic patients and the effect of improved public awareness on it. METHODS:...
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Pharmacological and Neuromodulatory Treatments for Panic Disorder: Clinical Trials from 2010 to 2018

Zugliani M, Cabo MC, Nardi AE, Perna G, Freire RC

OBJECTIVE: Treatment for panic disorder (PD) have evolved, although there is still a strong unmet need for more effective and tolerable options. The present study summarizes and discusses recent evidence...
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Internet-Delivered Psychological Treatment Options for Panic Disorder: A Review on Their Efficacy and Acceptability

Apolinário-Hagen J

BACKGROUND: Internet-delivered psychological treatments have been suggested as a chance to expand the access to professional help. However, little is known about the usefulness of different support formats and approaches...
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Fear Network Model in Panic Disorder: The Past and the Future

Lai CH

The core concept for pathophysiology in panic disorder (PD) is the fear network model (FNM). The alterations in FNM might be linked with disturbances in the autonomic nervous system (ANS),...
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