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Surveillance for Pancreatic Cancer in Chronic Pancreatitis

Chang JH

Pancreatic cancer can arise in the background of chronic pancreatitis (CP). The relative risks for pancreatic cancer in CP vary considerably according to other contributing factors such as disease duration,...
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Establishment of Patient-Derived Pancreatic Cancer Organoids from Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsies

Lee JH, Kim H, Lee SH, Ku JL, Chun JW, Seo HY, Kim SC, Paik WH, Ryu JK, Lee SK, Lowy AM, Kim YT

Background/Aims: Three-dimensional cultures of human pancreatic cancer tissue also known as “organoids” have largely been developed from surgical specimens. Given that most patients present with locally advanced and/or metastatic disease,...
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Daily Vigorous Intensity Physical Activity and Its Preventive Effect on Pancreatic Cancer

Park SK, Jung JY, Oh CM, Kim MH, Ha E, Kim Y, Nam DJ, Ryoo JH

Purpose There has been accumulating evidence for the preventive effect of high physical activity on cancer. However, it is still unclear which level of physical activity is associated with the...
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Intraoperative Radiotherapy for Resectable Pancreatic Cancer Using a Low-Energy X-Ray Source: Postoperative Complications and Early Outcomes

Cho Y, Kim JW, Kim HS, Park JS, Lee IJ

Purpose: We evaluated the safety, feasibility, and early treatment outcomes of intraoperative radiotherapy (IORT) using a lowenergy X-ray source. Materials and Methods: Patients with resectable pancreatic cancer were enrolled in this...
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Prognosis and Clinical Characteristics of Patients with Pancreatic Ductal Adenocarcinoma Diagnosed by Endoscopic Ultrasonography but Indeterminate on Computed Tomography

Ko SW, Kim TH, Song TJ, Kim SH, Seo DW, Yoon JH, Cho CM, Cho JH, Choi JH, Lee DW, Lee SH, Yoon SB, Lee TH, Kim GH, Chun HJ

Background/Aims: Endoscopic ultrasonography (EUS) provides high-resolution images and is superior to computed tomography (CT) scan in diagnosing small pancreatic ductal adenocarcinoma (PDAC). As a result, the use of EUS for...
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Distal migration of a partially covered duodenal stent requiring emergency surgical extraction

Campana LG, Fish R, Dickinson OT, McNamara MG, O’Dwyer ST, Laasch HU

Duodenal stenting is an established alternative for the palliation of malignant gastric outlet obstruction (MGOO). Despite being relatively rare, stent migration remains an issue of concern. We present a case...
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Metastatic tumors to the pancreas: Balancing clinical impression with cytology findings

Abdallah MA, Bohy K, Singal A, Xie C, Patel B, Nelson ME, Bleeker J, Askeland R, Abdullah A, Aloreidi K, Atiq M

Backgrounds/Aims: Metastatic lesions of the pancreas (PMET) account for 1%–5% of all malignant solid pancreatic lesions (SPL). In this study we evaluated the utility of endoscopic ultrasonography with fine needle...
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Solid Pseudopapillary Neoplasm of the Pancreas with Lymph Node Metastasis in a Young Male Patient

Park S, Park MG, Roh YH, Kim DK

Solid pseudopapillary pancreatic neoplasms are rare. The male-to-female ratio is 1:9, and metastasis occurs only in a few cases. A 39-year-old male with a solid pseudopapillary neoplasm (SPN) with lymph...
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Oncologic outcomes according to the location and status of resection margin in pancreas head cancer: role of radiation therapy in R1 resection

Sohn HJ, Kim H, Kim SJ, Lee KB, Han Y, Lee JM, Kang JS, Kwon W, Chie EK, Kim H, Jang JY

Purpose: The clinical significance of margin status in pancreatic head cancer is still controversial due to the nonstandardized definition of R status and pathologic reporting. This study aims to evaluate...
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First Course of treatment and Prognosis of Exocrine Pancreatic Cancer in Korea from 2006 to 2017

Kang MJ, Lim J, Han SS, Park HM, Park SJ, Won YJ, Kim SW

Purpose Hospital-based clinical studies have limitations in holistic assessment of cancer treatment and prognosis, as they omit out-of-hospital patients including elderly individuals. This study aimed to investigate trends in initial treatment...
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Four-Tier Pathologic Tumor Regression Grading System Predicts the Clinical Outcome in Patients Who Undergo Surgical Resection for Locally Advanced Pancreatic Cancer after Neoadjuvant Chemotherapy

Ahn S, Lee Jc, Kim J, Kim YH, Yoon YS, Han HS, Kim H, Hwang JH

Background/Aims: Neoadjuvant chemotherapy is increasingly utilized in patients with borderline or locally advanced pancreatic cancer (LAPC). However, the pathologic evaluation of tumor regression is not routinely performed or well established....
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Comparative Pre-clinical Efficacy of Chinese and Indian Cultivars of Bitter Melon (Momordica charantia) against Pancreatic Cancer

Kandhari K, Paudel S, Raina K, Agarwal C, Kant R, Wempe MF, Bryant CO, Agarwal R

Given the high rates of incidence and mortality associated with pancreatic cancer (PanC), there is a need to develop alternative strategies to target PanC. Recent studies have demonstrated that fruits...
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Effects of Meaning in Life and Social Support on Posttraumatic Growth in Pancreatic Cancer Survivors

Kim Y, Hwang B

Purpose: The purpose of this study was to examine the correlations among meaning in life, social support, and posttraumatic growth and to identify the factors related to posttraumatic growth in...
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Paradigm shift for defining the resectability of pancreatic cancer

Kang MJ, Kim SW

Supported by the expanding indications for neoadjuvant therapy (NAT) for advanced pancreatic cancer (PC), the concept of resectability has evolved from being mostly based on the anatomical tumor extent to...
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Development and External Validation of Survival Prediction Model for Pancreatic Cancer Using Two Nationwide Databases: Surveillance, Epidemiology and End Results (SEER) and Korea Tumor Registry System-Biliary Pancreas (KOTUS-BP)

Kang JS, Mok L, Heo JS, Han IW, Shin SH, Yoon YS, Han HS, Hwang DW, Lee JH, Lee WJ, Park SJ, Park JS, Kim Y, Lee H, Yu YD, Yang JD, Lee SE, Park IY, Jeong CY, Roh Y, Kim SR, Moon JI, Lee SK, Kim HJ, Lee S, Kim H, Kwon W, Lim CS, Jang JY, Park T

Background/Aims: Several prediction models for evaluating the prognosis of nonmetastatic resected pancreatic ductal adenocarcinoma (PDAC) have been developed, and their performances were reported to be superior to that of the...
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Longstanding postoperative fluid collection influences recurrence of pancreatic malignancy

Kim YJ, Cheon YK, Lee TY, Chang SH, Yu MH

Background/Aims: Postoperative abdominal fluid collection (PAFC) is a frequent complication of pancreatobiliary cancer surgery. The effects of the existence and duration of PAFC are not well known. This study aimed...
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Phase II Trial of Postoperative Adjuvant Gemcitabine and Cisplatin Chemotherapy Followed by Chemoradiotherapy with Gemcitabine in Patients with Resected Pancreatic Cancer

Lee KH, Chie EK, Im SA, Kim JH, Kwon J, Han SW, Oh DY, Jang JY, Kim JS, Kim TY, Bang YJ, Kim SW, Ha SW

Purpose Despite curative resection, the 5-year survival for patients with resectable pancreatic cancer is less than 20%. Recurrence occurs both locally and at distant sites and effective multimodality adjuvant treatment...
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Laparoscopic pancreaticoduodenectomy in pancreatic ductal adenocarcinoma

Choi M, Rho SY, Kim SH, Hwang HK, Lee WJ, Kang CM

Laparoscopic pancreatoduodenectomy (LPD) in pancreatic cancer is primarily criticized for its technical and oncological safety. Although solid evidence has not yet been established, many institutions are performing LPD for pancreatic...
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Safety and Efficacy of Ultrasound-Guided Percutaneous Core Needle Biopsy of Pancreatic and Peripancreatic Lesions Adjacent to Critical Vessels

Chung SH, Kang HJ, Lee HJ, Kim JS, Lee JK

Purpose To evaluate the safety and efficacy of ultrasound-guided percutaneous core needle biopsy (USPCB) of pancreatic and peripancreatic lesions adjacent to critical vessels. Materials and Methods Data were collected retrospectively from...
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Recent Strategies for Differentiation and Management of Incidental Pancreatic Cystic Lesions

Kim HJ

As pancreatic cysts are being identified with growing frequency due to the escalating use of cross-sectional imaging, optimal surveillance for patients with pancreatic cystic lesions is becoming an increasingly common...
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