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Clinical outcomes and technical description of unstented end to side pancreaticogastrostomy by small posterior gastrotomy

Bhoriwal SK, Kumar S, Deo S, Sharma J, Mishra A, Kumar N, Saikia J, Dhall K

Backgrounds/Aims: Morbidity following Whipple’s surgery largely depends upon the pancreatic stump anastomosis leak. Pancreaticogastrostomy is one of the techniques of pancreatic stump reconstruction and is described variously in the literature. Duct...
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Endoscopic Ultrasound–Guided Fiducial Placement for Stereotactic Body Radiation Therapy in Pancreatic Malignancy

Kim SH, Shin EJ

Stereotactic body radiation therapy (SBRT) is an important treatment option for pancreatic cancer, which is known to be one of the malignancies with the worst prognosis. However, the high radiation...
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Laparoscopic hybrid pancreaticoduodenectomy: Initial single center experience

Al-Sadairi AR, Mimmo A, Rhaiem R, Esposito F, Rached LJ, Tashkandi A, Zimmermann P, Memeo R, Sommacale D, Kianmanesh R, Piardi T

Backgrounds/Aims: Pancreaticoduodenectomy (PD) is the gold standard for the treatment of periampullary tumors. Many specialized centers have adopted the totally laparoscopic or hybrid laparoscopic PD (LPD). However, this procedure has...
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The Role of Imaging in Current Treatment Strategies for Pancreatic Adenocarcinoma

Rhee H, Park MS

In pancreatic cancer, imaging plays an essential role in surveillance, diagnosis, resectability evaluation, and treatment response evaluation. Pancreatic cancer surveillance in high-risk individuals has been attempted using endoscopic ultrasound (EUS)...
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Endoscopic Ultrasound-Guided Local Therapy for Pancreatic Neoplasms

Hwang JS, Joo HD, Song TJ

Surgical resection is considered the only treatment option for pancreatic cancer and other pancreatic neoplasms with malignant potential, such as neuroendocrine tumors, mucinous cystic neoplasms, and intraductal papillary mucinous neoplasms....
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Combination Treatment with Radiation and Alternating Electric Fields Causes Increased Apoptosis in Pancreatic Cancer Cell Lines

Jo Y, Oh G, Gi Y, Sung H, Yoon M

  • KMID: 2510076
  • Prog Med Phys.
  • 2020 Sep;31(S1):S32.
Purpose: Tumor treating fields (TTF) therapy is a non-invasive method that uses alternating electric fields to treat various types of cancer. This study demonstrates the combined effect of TTF and...
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Clinical outcomes of pancreaticoduodenectomy for pancreatic ductal adenocarcinoma depending on preservation or resection of pylorus

Kim YJ, Shin SH, Han IW, Ryu Y, Kim N, Choi DW, Heo JS

Backgrounds/Aims: The comparative effectiveness of pylorus-resecting pancreaticoduodenectomy (PRPD) and pylorus-preserving pancreaticoduodenectomy (PPPD) in pancreatic head cancer is still disputed. The aim of this study was to analyze the data obtained...
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Local Endoscopic Treatment of Locally Advanced Pancreatic Cancer

Hwang JS, Ko SW, So H, Song TJ

Pancreatic adenocarcinoma is one of the cancers with the poorest prognosis, and its incidence has gradually increased to become the 9th most common cancer in Korea in 2016. Surgical resection...
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Updates of Chemotherapy and Radiotherapy for Pancreatic Cancer

Sung MJ, Bang S

Pancreatic cancer is still one of the most aggressive malignancy, showing 10% of 5-year survival. Among the several reasons of the grave prognosis, the poor response to chemotherapeutic agents and...
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Prophylaxis of Venous Thromboembolism in Patients with Pancreatic Cancer

Lee KW, Lee JM, Lee HS

  • KMID: 2503586
  • J Dig Cancer Rep.
  • 2020 Jun;8(1):51-55.
Prognosis of patients with pancreatic cancer is poor due to difficulty in early diagnosis and low resectability rate at the time of diagnosis. Apart from the progression of cancer, venous...
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Obesity and Pancreatobiliary Disease

Lee H, Koh DH

Obesity has become a major medical and public health problem worldwide. Recent studies have shown that obesity is a chronic disease that is associated with many diseases, such as gallstone...
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Fatal progressive right heart failure in a pancreatic cancer patient

Byoun JT, Cho JY

Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare but fatal complication of cancer and causes pulmonary hypertension and acute/subacute right heart failure. PTTM is most commonly associated with gastric cancer...
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Yonsei Criteria, a Potential Linkage to Intratumoral Foxp3⁺/CD8⁺ Ratio for the Prediction of Oncologic Outcomes in Resected Left-Sided Pancreatic Cancer

Hwang HK, Lee SH, Kim HI, Kim SH, Choi J, Kang CM, Lee WJ

PURPOSE: This study sought to investigate associations among Yonsei criteria (tumor confined to the pancreas, intact fascia layer between the distal pancreas and the left adrenal gland and kidney, and...
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in vivo multiplex gene targeting with Streptococcus pyogens and Campylobacter jejuni Cas9 for pancreatic cancer modeling in wildtype animal

Chang YJ, Bae J, Zhao Y, Lee G, Han J, Lee YH, Koo OJ, Seo S, Choi YK, Yeom SC

Pancreatic ductal adenocarcinoma is a lethal cancer type that is associated with multiple gene mutations in somatic cells. Genetically engineered mouse is hardly applicable for developing a pancreatic cancer model,...
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Pancreatic Cancer in a Young Male in His Twenties

Baek SH, Lee SS, Kim JH, Kim SH, Lim J, Lee JS, Kim MH

Pancreatic cancer is one of the most lethal malignancies worldwide. The risk of developing pancreatic cancer increases with age. Pancreatic cancer is seen mostly in the elderly; patients under the...
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Endoscopic Transpapillary Gallbladder Stenting for Acute Cholecystitis in a Patient with Metastatic Pancreatic Cancer

Nam SH, Baek SH, Yoo DR, Choi SJ, Lee JS, Oh D, Kim MH

Percutaneous transhepatic gallbladder drainage is an effective treatment for acute cholecystitis in poor surgical candidates. Endoscopic gallbladder drainage procedures, such as endoscopic ultrasound-guided gallbladder drainage, endoscopic gallbladder stenting, and endoscopic...
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Neoadjuvant chemotherapy followed by total pancreatectomy with splenectomy and combined vascular resections after preoperative percutaneous transhepatic portal vein stent placement in locally advanced pancreatic cancer with portal vein total obliteration

Kook Y, Choi M, Park JY, Chung YE, Man-Deuk MD, Lee WJ, Kang CM

Pancreatic cancer is one of the most lethal malignant diseases in gastrointestinal system that only about 15-20% of the patients are potential candidates for resection at diagnostic stage. However, with...
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Recent topics on endoscopic ultrasonography-guided celiac plexus neurolysis

Yasuda I, Hanaoka T, Takahashi K, Araki Y, Doi S, Iwashita T, Iwata K, Mukai T

Endoscopic ultrasonography-guided celiac plexus neurolysis (EUS-CPN) is a widely practiced technique. Three sets of guidelines have recently been published and this procedure has become a major EUS technique. However, there...
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Selection of Optimal Adjuvant Chemotherapeutic Agents for Pancreatic Cancer Treatment

Lim JH

Pancreatic cancer generally has a dismal prognosis, with a 5-year overall survival rate of approximately 10%. At present, surgical resection is the only treatment with a curative aim; however, it...
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Therapeutic Co-targeting of WEE1 and ATM Downregulates PD-L1 Expression in Pancreatic Cancer

Jin MH, Nam AR, Park JE, Bang JH, Bang YJ, Oh DY

Purpose Pancreatic cancer (PC) is one of the most lethal cancers worldwide, but there are currently no effective treatments. The DNA damage response (DDR) is under investigation for the development of...
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