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This study reports a case of promyelocytic sarcoma that developed as a solitary sternal mass without any clinical evidence of acute promyelocytic leukemia. The case presented the diagnostic difficulties common...
We report a case of morphologically microgranular acute promyelocytic leukemia with PML/RARA fusion transcripts demonstrated by reverse transcriptase-PCR and cDNA sequencing, and no PML/RARA fusion detected by karyotype and FISH...
Park KU, Lee DS, She CJ, Ko EK, Park S, Cho HI, Han KS
KMID: 2226037
Korean J Clin Pathol.
2001 Aug;21(4):253-259.
BACKGROUND: The most noted rearrangement identified in acute promyelocytic leukemia (APL) involves the PML and RARa genes, which results in the formation of the PML/RARa gene fusion. In the fluorescence...
Oh SJ, Kim H, Ahn MJ, Kim IS, Jeong TJ, Choi IY, Chae JD, Lee WS, Cho YH, Lee YY
KMID: 2083418
Korean J Hematol.
2000 May;35(2):174-178.
Acute promyelocytic leukemia (APL/AML- M3) is a distinct subtype of acute myelogenous leukemia, which is characterized by unique morphologic, cytogenetic, molecular, and clinical features. In almost all APL patients, a...