- The role of adiponectin in the production of IL-6, IL-8, VEGF and MMPs in human endothelial cells and osteoblasts: implications for arthritic joints
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Lee YA, Ji HI, Lee SH, Hong SJ, Yang HI, Chul Yoo M, Kim KS
- KMID: 2155337
- Exp Mol Med.
- 2014 Jan;46(1):e72.
- doi: 10.1038/emm.2013.141
This study was performed to evaluate the contribution of adiponectin to the production of interleukin (IL)-6, IL-8, vascular endothelial growth factor (VEGF), matrix metalloproteinase (MMP)-1 and MMP-13 in human endothelial... -
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- Na+-Ca2+ exchanger modulates Ca2+ content in intracellular Ca2+ stores in rat osteoblasts
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Jung SY, Park YJ, Park YJ, Cha SH, Lee MZ, Suh CK
- KMID: 756068
- Exp Mol Med.
- 2007 Aug;39(4):458-468.
Na+ -Ca2+ exchanger (NCX) transports Ca2+ coupled with Na+ across the plasma membrane in a bi-directional mode. Ca2+ flux via NCX mediates osteogenic processes, such as formation of extracellular matrix... -
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- Inhibitory action of bisphosphonates on bone resorption does not involve the regulation of RANKL and OPG expression
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Kim YH, Kim GS, Baek JH
- KMID: 1081464
- Exp Mol Med.
- 2002 May;34(2):145-151.
The mechanism of inhibitory action of bisphosphonates on bone resorption is not fully elucidated. Osteoclast formation and activity are regulated by osteoblast-derived factors such as the osteoclast differentiating factor, receptor... -
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- The N- and C-terminal domains of parathyroid hormone-related protein affect differently the osteogenic and adipogenic potential of human mesenchymal stem cells
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Casado-Diaz A, Santiago-Mora R, Quesada JM
- KMID: 983981
- Exp Mol Med.
- 2010 Feb;42(2):87-98.
- doi: 10.3858/emm.2010.42.2.010
Parathyroid hormone-related protein (PTHrP) is synthesized by diverse tissues, and its processing produces several fragments, each with apparently distinct autocrine and paracrine bioactivities. In bone, PTHrP appears to modulate bone... -
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- The Effect of alpha MSH Analogues on Rat Bones
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Lim SK, Li SZ, Rhee Y, Chung SS, Jin YJ, Yook JI
- KMID: 1122009
- Yonsei Med J.
- 2002 Aug;43(4):500-510.
- doi: 10.3349/ymj.2002.43.4.500
Melanocortin is the downstream mediator of leptin signaling and absence of leptin signaling in ob/ob and db/db mice revealed the enhancement of bone formation through the central regulation. While alpha-melanocyte-stimulating... -
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