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MicroRNA-21 controls the development of osteoarthritis by targeting GDF-5 in chondrocytes

Zhang Y, Jia J, Yang S, Liu X, Ye S, Tian H

Osteoarthritis is a common cause of functional deterioration in older adults and is an immense burden on the aging population. Altered chondrogenesis is the most important pathophysiological process involved in...
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Effects of ageing and arthritic disease on nitric oxide production by human articular chondrocytes

Min BH, Kim HJ, Lim HJ, Park CS, Park SR

  • KMID: 1457545
  • Exp Mol Med.
  • 2001 Dec;33(4):299-302.
Nitric oxide (NO) has been considered as an important mediator in inflammatory phases and in loss of cartilage. In inflammatory arthritis, NO levels are correlated with disease activity and articular...
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