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Effects of Adamantyl Derivatives on Pharmacokinetic Behavior of Paclitaxel in Rats

Kim KM, Lee K, Jang K, Moon YS, Lee HJ, Rhie SJ

Paclitaxel (PTX) is one of the most frequently used anticancer agent for treating refractory ovarian cancer, metastatic breast cancer and non-small cell lung cancer. However, its oral administration is impeded...
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Absorption Study of Genistein Using Solid Lipid Microparticles and Nanoparticles: Control of Oral Bioavailability by Particle Sizes

Kim JT, Barua S, Kim H, Hong SC, Yoo SY, Jeon H, Cho Y, Gil S, Oh K, Lee J

In this study, the effect of particle size of genistein-loaded solid lipid particulate systems on drug dissolution behavior and oral bioavailability was investigated. Genistein-loaded solid lipid microparticles and nanoparticles were...
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