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Concomitant AID Expression and BCL7A Loss Associates With Accelerated Phase Progression and Imatinib Resistance in Chronic Myeloid Leukemia

Yu N, Shin S, Choi JR, Kim Y, Lee KA

No abstract available.
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Activation of KRAS promotes the mesenchymal features of basal-type breast cancer

Kim RK, Suh Y, Yoo KC, Cui YH, Kim H, Kim MJ, Kim IG, Lee SJ

Basal-type breast cancers are among the most aggressive and deadly breast cancer subtypes, displaying a high metastatic ability associated with mesenchymal features. However, the molecular mechanisms underlying the maintenance of...
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Real-Time PCR analysis of af4 and dek genes expression in acute promyelocytic leukemiat (15;17)patients

Savli H, Sirma S, Nagy B, Aktan M, Dincol G, Salcioglu , Sarper N, Ozbek U

  • KMID: 1097111
  • Exp Mol Med.
  • 2004 Jun;36(3):279-282.
Among several newly identified oncogenes, dek and af4 are attractive targets for researchers interested with leukemia. In this study quantitative Real-Time RT-PCR technique was used to define alterations in expression...
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LIN28B confers radio-resistance through the posttranscriptional control of KRAS

Jeong SH, Wu HG, Park WY

To screen the differentially expressed microRNAs related to radio-resistance, we compared the microRNA profiles of lung cancer cells with different responses to ionizing radiation (IR). Of 328 microRNAs in microarray,...
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A Novel Translocation t(1;5)(p32;q31) that Was Not Associated with the TAL1 Rearrangement in a Case of T Lymphoblastic Leukemia/Lymphoma

Cho HS, Kim MK, Bae YK

Chromosome 1 band p32 (1p32) aberrations are common in T lymphoblastic leukemia/lymphoma (T-ALL/LBL). Two types of 1p32 aberrations include translocations with different partners and submicroscopic interstitial deletion. Both aberrations are...
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Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide

Cha HS, Bae EK, Ahn JK, Lee J, Ahn KS, Koh EM

Inadequate apoptosis contributes to synovial hyperplasia in rheumatoid arthritis (RA). Recent study shows that low expression of Puma might be partially responsible for the decreased apoptosis of fibroblast-like synoviocytes (FLS)....
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