- In-Vitro Study of Urokinase Thrombolysis Following Stereotactic Aspiration of Intracerebral Hematoma
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Son W, Park J, Kang DH, Han YM, Choi YJ, Ohk B
- KMID: 2501726
- J Korean Neurosurg Soc.
- 2020 May;63(3):380-385.
- doi: 10.3340/jkns.2018.0224
Objective : A consensus regarding the ideal regimen for urokinase (UK) thrombolysis subsequent to stereotactic spontaneous intracerebral hemorrhage aspiration has yet to be established. The purpose of this study is... -
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- Development and validation of a UPLC-MS/MS method for the quantification of acetaminophen in human plasma and its application to pharmacokinetic studies
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Cha J, Kim BK, Gwon MR, Lee J, Ohk B, Kang WY, Lim MS, Seong SJ, Kim HJ, Lee HW, Yoon YR
- KMID: 2383597
- Transl Clin Pharmacol.
- 2016 Mar;24(1):30-36.
- doi: 10.12793/tcp.2016.24.1.30
We developed an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the determination of acetaminophen concentration in human plasma. Following protein precipitated extraction, the analytes were separated and analyzed using... -
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- Metabolomic analysis of healthy human urine following administration of glimepiride using a liquid chromatography-tandem mass spectrometry
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Do EY, Gwon MR, Kim BK, Ohk B, Lee HW, Kang WY, Seong SJ, Kim HJ, Yoon YR
- KMID: 2386763
- Transl Clin Pharmacol.
- 2017 Jun;25(2):67-73.
- doi: 10.12793/tcp.2017.25.2.67
Glimepiride, a third generation sulfonylurea, is an antihyperglycemic agent widely used to treat type 2 diabetes mellitus. In this study, an untargeted urinary metabolomic analysis was performed to identify endogenous... -
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- Determination of sumatriptan in human plasma using liquid chromatography-mass spectrometry for pharmacokinetic study in healthy Korean volunteers
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Cho S, Jegal M, Ohk B, Kim BK, Gwon MR, Kang WY, Seong SJ, Kim HJ, Lee HW, Yoon YR
- KMID: 2386768
- Transl Clin Pharmacol.
- 2017 Jun;25(2):106-111.
- doi: 10.12793/tcp.2017.25.2.106
This study describes the development of an analytical method to determine sumatriptan levels in human plasma using high performance liquid chromatography (HPLC) coupled with triple quadrupole tandem mass spectrometry (MS/MS)... -
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- Should Cerebral Angiography Be Avoided within Three Hours after Subarachnoid Hemorrhage?
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An H, Park J, Kang DH, Son W, Lee YS, Kwak Y, Ohk B
- KMID: 2457942
- J Korean Neurosurg Soc.
- 2019 Sep;62(5):526-535.
- doi: 10.3340/jkns.2018.0238
OBJECTIVE: While the risk of aneurysmal rebleeding induced by catheter cerebral angiography is a serious concern and can delay angiography for a few hours after a subarachnoid hemorrhage (SAH), current... -
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- Deficiency of Lipocalin-2 Promotes Proliferation and Differentiation of Osteoclast Precursors via Regulation of c-Fms Expression and Nuclear Factor-kappa B Activation
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Kim HJ, Ohk B, Kang WY, Seong SJ, Suk K, Lim MS, Kim SY, Yoon YR
- KMID: 2156281
- J Bone Metab.
- 2016 Feb;23(1):8-15.
- doi: 10.11005/jbm.2016.23.1.8
BACKGROUND: Lipocalin-2 (LCN2), a small glycoprotein, has a pivotal role in diverse biological processes such as cellular proliferation and differentiation. We previously reported that LCN2 is implicated in osteoclast formation... -
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