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The Update of Treatment for Primary Intestinal Lymphangiectasia

Kwon Y, Kim MJ

Intestinal lymphangiectasia is a rare disease which is causing protein-losing enteropathy. Treatment of intestinal lymphangiectasia can be a challenge for clinicians because of the lack of specific guidelines regarding pharmacological indications....
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Systemic Treatment of Advanced Gastroenteropancreatic Neuroendocrine Tumors in Korea: Literature Review and Expert Opinion

Yoo C, Oh CR, Kim ST, Bae WK, Choi HJ, Oh DY, Lee MA, Ryoo BY

Neuroendocrine tumors (NETs) are a group of malignancies arising from neuroendocrine cells and frequently originate in the gastrointestinal tract and pancreas. Although curative resection is the main treatment for localized...
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Role of 68Ga-DOTATATE PET/CT in a Case of SDHB-Related Pterygopalatine Fossa Paraganglioma Successfully Controlled with Octreotide

Jha A, Patel M, Baker E, Gonzales MK, Ling A, Millo C, Knue M, Civelek AC, Pacak K

We describe an unusual case of a 42-year-old female with an unresectable succinate dehydrogenase subunit B (SDHB)-related pterygopalatine fossa paraganglioma. She underwent somatostatin receptor imaging with 68Ga-DOTA(0)-Tyr(3)-octreotate (68Ga-DOTATATE) positron emission...
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Serious Necrotizing Enterocolitis in a Neonate Treated with Octreotide for Congenital Chylothorax

Jo MJ, Kim DH, Kim HS

The somatostatin analog octreotide has recently been introduced in the treatment of infants with chylothorax. The safety profile of octreotide has not been fully evaluated. Octreotide reduces the splanchnic blood...
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Medical Treatment with Somatostatin Analogues in Acromegaly: Position Statement

Chin SO, Ku CR, Kim BJ, Kim SW, Park KH, Song KH, Oh S, Yoon HK, Lee EJ, Lee JM, Lim JS, Kim JH, Kim KJ, Jin HY, Kim DJ, Lee KA, Moon SS, Lim DJ, Shin DY, Kim SH, Kwon MJ, Kim HY, Kim JH, Kim DS, Kim CH

Acromegaly is a chronic disorder caused by excessive growth hormone (GH) secretion. In most cases, the excess GH originates from GH-producing pituitary adenomas. Surgery is the preferred first-line treatment for...
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Medical Treatment with Somatostatin Analogues in Acromegaly: Position Statement

Chin SO, Ku CR, Kim BJ, Kim SW, Park KH, Song KH, Oh S, Yoon HK, Lee EJ, Lee JM, Lim JS, Kim JH, Kim KJ, Jin HY, Kim DJ, Lee KA, Moon SS, Lim DJ, Shin DY, Kim SH, Kwon MJ, Kim HY, Kim JH, Kim DS, Kim CH

The Korean Endocrine Society (KES) published clinical practice guidelines for the treatment of acromegaly in 2011. Since then, the number of acromegaly cases, publications on studies addressing medical treatment of...
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Somatostatin Treatment in Two Cases of Chyle Fistula after Neck Dissection

Ahn D, Lee DJ, Sohn JH, Yoon SP

The use of somastostatin in chyle fistula that occurs after neck dissection is a new approach that has been reported in few cases. We report two cases of chyle fistula...
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Is there a relationship between beginning time and efficiency of octreotide in the treatment of experimental acute pancreatitis?

Kafali ME, Gul M, Alptekin H, Sahin M, Toy H, Akoz M

  • KMID: 2324824
  • J Korean Surg Soc.
  • 2012 May;82(5):296-301.
PURPOSE: The efficacy of octreotide in the treatment of acute pancreatitis is controversial. Octreotide treatment for acute pancreatitis often shows poor correlation between results obtained in experimental studies and results...
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The Effect of Octreotide LAR on GH and TSH Co-Secreting Pituitary Adenoma

Kim NK, Hah YJ, Lee HY, Kim SJ, Kim MK, Park KG, Kim E, Chang H, Kim HS

Growth hormone (GH) and thyroid stimulating hormone (TSH)-secreting pituitary adenomas are very rare and they account for only 0.5% for all pituitary adenomas. These adenomas are usually treated with surgery,...
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Sustained Maintenance of Normal Insulin-like Growth Factor-I during Pregnancy and Successful Delivery in an Acromegalic Patient with Octreotide-LAR(R) Treatment

Kim SK, Jung JH, Kim JH, Hur KY, Tan AH, Kim HK, Lee JI, Chung HS, Kim KW

We report here on a 34-year-old Korean woman with active acromegaly and who received Octreotide-LAR(R) for 12 months following transsphenoidal pituitary surgery. During Octreotide-LAR(R) treatment, the clinical improvement was paralleled...
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Acromegaly with Diabetes Insipidus after Pituitary Tumor Removal: Successful Pregnancy and Delivery

Kim SH, Kim JI, Park YM, Won IS, Shin KC, Jo Y, Lee S, Kim YS, Lee KY, Park IB

A 33-year-old woman visited our hospital because of oligomenorrhea. Acromegaly was diagnosed based on elevated insulin like growth factor-I (IGF-I) and paradoxical growth hormone (GH) rise in oral glucose tolerance...
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Effect of Octreotide on Patients with Malignant Bowel Obstruction

Park JC, Jang YS, Jeon EK, Kim DK, Lee WH, Lee GJ, You SY, Choi HH, Park SY

  • KMID: 2305370
  • Korean J Hosp Palliat Care.
  • 2009 Dec;12(4):194-198.
PURPOSE: Malignant bowel obstruction causes gastrointestinal symptoms and leads to diminished quality of life in patients with advanced cancer. Several studies have shown the efficacy of octreotide for the relief...
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A clinical study of congenital chylothorax and octreotide therapy

Oh UG, Choi KE, Kim KA, Ko SY, Lee YK, Shin SM

PURPOSE: Congenital chylothorax is an accumulation of lymphatic fluid within the pleural space. It is a common cause of unidentified hydrops fetalis. We examined the perinatal history, clinical manifestation, diagnosis,...
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A Case of Intestinal Pseudoobstruction Associated with Systemic Sclerosis Successfully Treated with Erythromycin and Octreotide

Yoon HS, Seo TH, Jo HS, Lee EJ, Kim BS, Kim HR, Lee SH

  • KMID: 2334848
  • J Korean Rheum Assoc.
  • 2007 Dec;14(4):379-383.
Systemic sclerosis is an autoimmune disease, characterized by inflammation, microangiopathy and fibrosis in the skin and various intestinal organs. Gastrointestinal involvement is one of the major causes of serious morbidity,...
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Two Cases of Acromegaly with Empty Sella Syndrome Treated by Long-Acting Release Octreotide

Kim DJ, Seo YJ, Kim NH, Chung HS, Eun CR, Choi HJ, Kim HS, Yang SJ, Park J, Yoo HJ, Park SY, Lee YJ, Ryu OH, Lee KW, Kim HY, Seo JA, Kim SG, Kim NH, Choi KM, Baik SH, Choi DS

Two cases of typical acromegaly with empty sella syndrome presented to our institution. In the natural course of untreated pituitary adenoma, empty sella syndrome may result from necrosis by infarction...
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Two cases of postoperative chylothorax treated with parenteral octreotide and conservative therapy

Choi EJ, Lee S

Chylothorax is a rare complication following cardiac surgery for congenital heart diseases. Although conservative management is successful in the majority of cases, surgical intervention is required in a refractory one....
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A Case of Successful Management of Sarcoidosis with Chylothorax Using Octreotide

Jung KS, Moon JA, Yoon SH, Byun MK, Jung WY, Jung JH, Choi SB, Kim DJ, Pyo JY, Kim YS, Kim SK, Chang J, Kim SK, Park MS

Sarcoidosis is a multi-system granulomatous disorder of an unknown etiology and affects individuals worldwide. It is characterized pathologically by the presence of non-caseating granulomas in more than one involved organ....
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Treatment of Congenital Chylothorax in a Premature Infant using Octreotide

Ahn YJ, Jeon YH, Kim SS, Park JO, Kim CH

  • KMID: 2099112
  • J Korean Soc Neonatol.
  • 2006 Nov;13(2):261-266.
Chylothorax, defined as escape of chyle from the thoracic duct into the thoracic cavity, is the most common cause of pleural effusion during the neonatal period. The use of octreotide,...
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A Case of Intestinal Lymphangiectasia Improved with Antiplasmin and Octreotide Treatment

Yu SK, Choi JM, Yoo JH, Kim DK, Shin SJ, Lee KM, Yoo BM, Hahm KB, Kim JH, Han JH

  • KMID: 2143664
  • Korean J Gastrointest Endosc.
  • 2006 Oct;33(4):248-252.
Intestinal lymphangiectasia is characterized by protein- losing enteropathy, and is diagnosed by a small bowel biopsy demonstrating dilated lymphatics in the mucosa, submucosa and serosa in the absence of coexistent...
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Appropriate Premedication for Prevention on Post-ERCP Pancreatitis: A Randomized and Prospective Study

Yi SY

OBJECTIVES: Pancreatitis is the most common and serious complication of ERCP. On the basis of several reports, corticosteroid, octreotide, or calcium channel blocker might be effective in this regard. The...
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