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Metabolism-Centric Overview of the Pathogenesis of Alzheimer's Disease

Kang S, Lee YH, Lee JE

Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia. AD is characterized by the extracellular amyloid beta (Aβ) plaques and intraneuronal deposits of neurofibrillary...
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Fenofibrate regulates obesity and lipid metabolism with sexual dimorphism

Yoon MC, Jeong SH, Nicol CJ, Lee HH, Han MY, Kim JJ, Seo YJ, Ryu CY, Oh GT

  • KMID: 1121103
  • Exp Mol Med.
  • 2002 Dec;34(6):481-488.
To determine whether the PPARalpha agonist fenofibrate regulates obesity and lipid metabolism with sexual dimorphism, we examined the effects of fenofibrate on body weight, white adipose tissue (WAT) mass,...
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B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation

Kim YH, Choi BH, Cheon HG, Do MS

B cell activation factor (BAFF) is a novel member of the TNF ligand superfamily, mainly produced by myeloid cells. BAFF has been shown to participate in B-cell survival and B-...
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Anti-obesity activity of diglyceride containing conjugated linoleic acid in C57BL/6J ob/ob mice

Hue JJ, Lee KN, Jeong JH, Lee SH, Lee YH, Jeong SW, Nam SY, Yun YW, Lee BJ

This study was to investigate the anti-obesity effects of diglyceride (DG)-conjugated linoleic acid (CLA) containing 22% CLA as fatty acids in C57BL/6J ob/ob male mice. There were four experimental groups...
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