- Involvement of GADD153 and cardiac ankyrin repeat protein in cardiac ischemia-reperfusion injury
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Lee MJ, Kwak YK, You KR, Lee BH, Kim DG
- KMID: 1088599
- Exp Mol Med.
- 2009 Apr;41(4):243-252.
- doi: 10.3858/emm.2009.41.4.027
Oxidative stress is critical for causing cardiac injuries during ischemia-reperfusion (IR), yet the molecular mechanism for this remains unclear. In the present study, we observe that hypoxia and reoxygenation, a... -
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- Association of DNA-dependent protein kinase with hypoxia induciblefactor-1 and its implication inresistance to anticancer drugs in hypoxic tum or cells
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Um JH, Kang CD, Bae JH, Shin GG, Kim DW, Kim DW, Chung BS, Kim SH
- KMID: 1097105
- Exp Mol Med.
- 2004 Jun;36(3):233-242.
Tumor hypoxia contributes to the progression of a malignant phenotype and resistance to ionizing radiation and anticancer drug therapy. Many of these effects in hypoxic tumor cells are mediated by... -
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- Heat shock protein 70 alters the endosome-lysosomal localization of huntingtin
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Kang BS, Ahn JY, Kim MK, Kim HJ, Kang L, Lim HC, Park KS, Lee JS, Seo JS, Cha CI, Kim SU, Park YJ, Kim M
- KMID: 1103679
- Exp Mol Med.
- 2007 Feb;39(1):38-46.
Huntington's disease is caused by CAG trinucleotide expansions in the gene encoding huntingtin. N- terminal fragments of huntingtin with polyglutamine produce aggregates in the endosome-lysosomal system, where proteolytic fragments of... -
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