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Sirtuin-2 inhibition affects hippocampal functions and sodium butyrate ameliorates the reduction in novel object memory, cell proliferation, and neuroblast differentiation

Jung HY, Yoo DY, Kim JW, Kim DW, Choi JH, Chung JY, Won MH, Yoon YS, Hwang IK

We investigated the effects of the sirtuin-2 (SIRT2) inhibitor AK-7 on novel object memory, cell proliferation, and neuroblast differentiation in the dentate gyrus. In addition, we also observed the relationships...
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The Effect of Fluoxetine on Behaviors in Transient Forebrain Ischemic Gerbil

Li H, Kim DH, Won MH, Yan JJ

  • KMID: 854048
  • Korean J Psychopharmacol.
  • 2006 Nov;17(6):565-572.
OBJECTIVE: This study aims to explore the effect of fluoxetine on memory, locomotor and depressive behavior in transient forebrain ischemic model of gerbil. METHODS: Doses of fluoxetine (10, 40 mg/kg)...
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