- XperCT-guided Intra-cisterna Magna Injection of Streptozotocin for Establishing an Alzheimer’s Disease Model Using the Cynomolgus Monkey (Macaca fascicularis)
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Park J, Won J, Jeon CY, Lim KS, Choi WS, Park Sh, Seo J, Cho J, Seong JB, Yeo HG, Kim K, Kim YG, Kim M, Yi KS, Lee Y
- KMID: 2537960
- Exp Neurobiol.
- 2022 Dec;31(6):409-418.
- doi: 10.5607/en22027
Till date, researchers have been developing animal models of Alzheimer’s disease (AD) in various species to understand the pathological characterization and molecular mechanistic pathways associated with this condition in humans... -
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- Codelivery of IL-7 Augments Multigenic HCV DNA Vaccine-induced Antibody as well as Broad T Cell Responses in Cynomolgus Monkeys
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Park SH, Song MY, Nam HJ, Im SJ, Sung YC
- KMID: 2150675
- Immune Netw.
- 2010 Dec;10(6):198-205.
- doi: 10.4110/in.2010.10.6.198
BACKGROUND: A crucial limitation of DNA vaccines is its weak immunogenicity, especially in terms of eliciting antibody responses in non-human primates or humans; therefore, it is essential to enhance immune... -
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- Establishment of a Research and Assessment System Using High Quality Non-Human Primates
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Hyun BH, Kang BC, Kim CK, Kim HS, Suh JG, Cho F
- KMID: 2114716
- Lab Anim Res.
- 2010 Dec;26(4):449-457.
- doi: 10.5625/lar.2010.26.4.449
At present, eight non-human primate research facilities exist in Korea to examine the validity and safety of new bio-products, and to generate model animal systems using primates of low health... -
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