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Gut microbiota and nonalcoholic fatty liver disease

Kim B, Kim B

The gut microbiota has been reported to exert a significant influence on various physiological responses of hosts. Extensive evidence has recently emerged linking metabolic and cardiovascular disorders to the gut...
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Association between Muscle Mass Deficits and Metabolic Dysfunction-Associated Fatty Liver Disease in Adults with Body Mass Index Less than 23 kg/m2

Lee MY, Choi HJ, Oh HJ

Background: Metabolic dysfunction-associated fatty liver disease (MAFLD) can be diagnosed regardless of a significant history of alcohol consumption or other causes of liver disease when a fatty liver is accompanied...
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Effects of sleeve gastrectomy and Roux-en-Y gastric bypass on non-alcoholic fatty liver disease in Iranians with morbid obesity

Aghakhani L, Haghighat N, Amini M, Masoumi SJ

Background: Morbid obesity increases the risk of various diseases, including non-alcoholic fatty liver disease (NAFLD). Bariatric surgery is one of the most effective tools to achieve significant weight loss and...
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Experimental model and novel therapeutic targets for non-alcoholic fatty liver disease development

Jin Y, Heo KS

Non-alcoholic fatty liver disease (NAFLD) is a complex disorder characterized by the accumulation of fat in the liver in the absence of excessive alcohol consumption. It is one of the...
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Correspondence on Letter regarding “Non-alcoholic fatty liver disease: Definition and subtypes”

Han SK, Baik SK, Kim MY

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Letter regarding “Non-alcoholic fatty liver disease: Definition and subtypes”

Jeong S, Lim Y, Lee SK, Han HW

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Impact of fatty liver on long-term outcomes in chronic hepatitis B: a systematic review and matched analysis of individual patient data meta-analysis

Wong YJ, Nguyen VH, Yang HI, Li J, Le MH, Wu WJ, Han NX, Fong KY, Chen E, Wong C, Rui F, Xu X, Xue Q, Hu XY, Leow WQ, Goh GBB, Cheung R, Wong G, Wong VWS, Yu MW, Nguyen MH

Background/Aims: Chronic hepatitis B (CHB) and fatty liver (FL) often co-exist, but natural history data of this dual condition (CHB-FL) are sparse. Via a systematic review, conventional meta-analysis (MA) and...
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Beneficial Effects of a Curcumin Derivative and Transforming Growth Factor-β Receptor I Inhibitor Combination on Nonalcoholic Steatohepatitis

Ha KB, Lee ES, Park NW, Jo SH, Shim S, Kim DK, Ahn CM, Chung CH

Background: Curcumin 2005-8 (Cur5-8), a derivative of curcumin, improves fatty liver disease via AMP-activated protein kinase activation and autophagy regulation. EW-7197 (vactosertib) is a small molecule inhibitor of transforming growth...
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Toward acquisition protocol standardization for estimating liver fat content using ultrasound attenuation coefficient imaging

Ferraioli G, Raimondi A, De Silvestri A, Filice C, Barr RG

Purpose: This study’s primary aim was to assess factors affecting ultrasound attenuation coefficient (AC) measurement repeatability using the Canon ultrasound (US) system. The secondary aim was to evaluate whether similar...
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Independent and Synergistic Associations of Aerobic Physical Activity and Resistance Exercise with Nonalcoholic Fatty Liver Disease

Yang HJ, Hong YP, Yoon TY, Ryoo JH, Choi JM, Oh CM

Background/Aims: This study aimed to examine the independent and synergistic association of aerobic physical activity and resistance exercise with nonalcoholic fatty liver disease (NAFLD) using a nationwide representative database. Methods: This...
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Fibrotic Burden in the Liver Differs Across Metabolic Dysfunction-Associated Fatty Liver Disease Subtypes

Lim TS, Chun HS, Kim SS, Kim JK, Lee M, Cho HJ, Kim SU, Cheong JY

Background/Aims: Metabolic dysfunction-associated fatty liver disease (MAFLD) is categorized into three subtypes: overweight/obese (OW), lean/normal weight with metabolic abnormalities, and diabetes mellitus (DM). We investigated whether fibrotic burden in liver...
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Exercise Capacity and Pulmonary Capacitance Are Attenuated in Patients with Nonalcoholic Steatohepatitis

Donkor J, Carlson AR, Ziegler BL, Johnston JI, Cho J, Johnson BD., Kim CH

Purpose: The study was to investigate exercise capacity (peak oxygen uptake [peak VO2 ]) and pulmonary capacitance (GXcap), which is an estimate of pulmonary vascular capacitance, in patients with nonalcoholic...
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Fatty Liver & Diabetes Statistics in Korea: Nationwide Data 2009 to 2017

Han E, Han KD, Lee Yh, Kim KS, Hong S, Park JH, Park CY, on Behalf of Fatty Liver Research Group of the Korean Diabetes Association

Background: This study investigated the changes of fatty liver disease prevalence in general Korean population. Methods: This study analyzed data from the Korean National Health Insurance Service from 2009 to 2017...
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High Sodium Intake, as Assessed by Urinary Sodium Excretion, Is Associated with Nonalcoholic Fatty Liver Disease or Sarcopenia

Han E, Kim MK, Im SS, Kim HS, Kwon TK, Jang BK

Background/Aims: We explored whether high sodium intake, assessed by urinary excretion, determines the risk of sarcopenia and nonalcoholic fatty liver disease (NAFLD). Methods: We analyzed 10,036 adult participants with normal kidney...
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Protective effect of chlorophyllremoved ethanol extract of Lycium barbarum leaves against nonalcoholic fatty liver disease

Lee H, Bae EY, Kim KA, Ly SY

Purpose: This study was conducted to establish whether an ethanol extract of Lycium barbarum leaves (LLE) and an ethanol extract of Lycium barbarum leaves from which chlorophyll has been removed,...
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Changes in the Prevalences of Obesity, Abdominal Obesity, and Non-Alcoholic Fatty Liver Disease among Korean Children during the COVID-19 Outbreak

Song K, Yang J, Lee HS, Kim SJ, Lee M, Suh J, Kwon A, Kim HS, Chae HW

Purpose: We aimed to investigate the prevalences of obesity, abdominal obesity, and non-alcoholic fatty liver disease (NAFLD) among children and adolescents during the coronavirus disease 2019 (COVID-19) outbreak. Materials and Methods:...
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Implications of comorbidities in nonalcoholic fatty liver disease

Song SJ, Wong VWS

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Changing the nomenclature from nonalcoholic fatty liver disease to metabolic dysfunction-associated fatty liver disease is more than a change in terminology

Yoon EL, Jun DW

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Performance of Simple Fibrosis Score in Non-Alcoholic Fatty Liver Disease with and without Type 2 Diabetes

Chung SM, Kang MK, Moon JS, Park JG

This cross-sectional study enrolled 267 patients with metabolic risk factors and established non-alcoholic fatty liver disease in the prospective cohort. The performance of fibrosis-4 (FIB-4) score (≥1.3) to diagnose advanced...
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Non-obese or lean nonalcoholic fatty liver disease matters, but is it preventable or inevitable in light of its risk factors?

Jang H, Kim W

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