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Effects of Intravenous Administration of Nimodipine on Cerebral Pial Vessels after Experimental Subarachnoid Hemorrhage in Rabbits

Hwang SG, Lee YW

  • KMID: 2067974
  • J Korean Neurosurg Soc.
  • 1993 Jul;22(7):834-844.
No abstract available.
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Nimodipine Treatment after Aneurysmal Subarachnoid Hemorrhage and Operation

Han DH, Chung YS, Lee SH

  • KMID: 2067900
  • J Korean Neurosurg Soc.
  • 1991 Mar;20(1-3):28-35.
Fifty-one consecutive 186 patients with aneurysmal subarachnoid hemorrhage were treated from the day of admission with nimodipine which was given first as an IV infusion at 30ug/kg/hr for 1 week...
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Experimental Study of the Effect of Nimodipine on CSF Formation

Song JH, Park YK, Chung HS, Suh JK, Lee HK, Lee KC, Chu CW

  • KMID: 2067979
  • J Korean Neurosurg Soc.
  • 1993 Sep;22(9):947-952.
The author has performed an experimental study in order to investigate the effect of nimodipine on the production of CSF in 12 cats. The cats were divided into 2 groups,...
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Effect of Nimodipine on Experimental Cerebral Vasospasm: Electron Microscopic Studies

Shim SI, Shin KM

  • KMID: 2187748
  • J Korean Neurosurg Soc.
  • 1990 Sep;19(8-9):1179-1183.
In order to evaluate the effect on nimodipine on the cerebral vasospasm, twelve adult mongrel dogs were studied in this experiment. This animals were divided into 2 groups ; Intracisternal...
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Clinical Variables Correlated with Numbers of Intra-arterial Nimodipine Infusion in Patients with Medically Refractory Cerebral Vasospasm

Kim SY, Kim KH, Cho JH, Kim YD

OBJECTIVE: The objective of this study was to find out the clinical variables correlated with repeated intra-arterial (IA) nimodipine infusions in patients with medically refractory cerebral vasospasm (CV) following subarachnoid...
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Controlled Study of Nimodipine in Patients with Aneurysmal Subarachnoid Hemorrhage:Effect on the Short-Term Outcome and Safety Assessment

Paek SH, Oh CW, Han DH

  • KMID: 1671273
  • J Korean Neurosurg Soc.
  • 1996 Dec;25(12):2472-2477.
From January 1996 to September 1996, we enrolled 30 patients with a clinical status over Hunt and Hess grade IV, presenting within 5 days after spontaneous subarachnoid hemorrhage to determine...
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Effects of Nimodipine on Seizure Pattern and Electroencephalography of Penicillin-Induced Temporal Epileptic Rat

Hwang JH, Choi CR

  • KMID: 1692125
  • J Korean Neurosurg Soc.
  • 1993 Mar;22(3):413-418.
In order to investigate the antiepileptic effects of calcium antagonist, nimodipine, we studied the changes of seizure pattern and electroencephalographic finding of the epileptic rats before and after nimodipine administration...
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The Effects of Nimodipine on Neurological and Pathological Findings Following Experimental Focal Cerebral Ischemia

Park SH, Lee KH, Lee KC

  • KMID: 2339565
  • J Korean Neurosurg Soc.
  • 1990 Jan;19(1):5-13.
Two major factors, delayed hypoperfusion and membrane failure influence the sequelae of cerebral ischemic injury. Calcium ions play a major role in both pathophysiological mechanisms. Calcium channel blockers are a...
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Nimodipine as a potential pharmacological tool for characterizing R-type calcium currents

Oh SB

  • KMID: 1607140
  • Korean J Physiol Pharmacol.
  • 2001 Dec;5(6):511-519.
Nimopidine, one of dihydropyridine derivatives, has been widely used to pharmacologically identify L-type Ca currents. In this study, it was tested if nimodipine is a selective blocker for L-type Ca...
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The Preventive Effect of Nimodipine on the Cisplatin Induced Neuropathy

Kim CH, Choi HC, Roh GH

  • KMID: 2178721
  • J Korean Acad Rehabil Med.
  • 2003 Feb;27(1):90-95.
OBJECTIVE: Cisplatin has effectiveness in the treatment of solid tumor by active cytotoxic action, but with significant side effects such as peripheral neuropathy. To investigate the prevention of neuropathy, nimodipine...
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The Effect of the Calcium Antagonist Nimodipine on Cerebral Cortical Blood Flow in the Experimentally Induced Subarachnoid Hemorrhage

Huh SK, Lee KC

  • KMID: 2187591
  • J Korean Neurosurg Soc.
  • 1987 Dec;16(4):1091-1104.
The effect of the calcium antagonist nimodipine on the feline cerebral cortical blood flow in experimentally induced subarachnoid hemorrhage(SAH) was studied. Cerebral cortical blood flow was measured in the middle...
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Clinical Trial of Nimodipine in Patients with Aneurysmal Subarachnoid Hemorrhage

Lee KS, Lee KC

  • KMID: 1953426
  • J Korean Neurosurg Soc.
  • 1986 Jun;15(2):237-244.
Forty-three patients with aneurysmal subarachnoid hemorrhage entered and thirth-three of them completed the Nimodipine trial at the Yonsei University Hospital, under the Study Protocol provided by the Bayer AG, to...
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Effect of Nimodipine, Phenylephrine, Pentobarbital, and Ketamine on Cerebral Energy Metabolism in Cerebral Air Embolized Cats: in vivo 31 P Nuclear Magnetic Resonance Spectroscopy Study

Han SM

The author used in vivo P nuclear magnetic resonance spectroscopy to determine the effect of cerebral air embolization and nimodipine, phenylephrine, pentobarbital and ketamine on changes of pH and PCr/Pi...
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Effect of Nimodipine on Ischemic Brain Edema of Gerbil

Lee IK, Yoon BW, Rho JK

  • KMID: 2065934
  • J Korean Neurol Assoc.
  • 1991 Dec;9(4):413-417.
The mechanisms involved in brain neuronal damage in ischemia are related to the elevation of cytosolic calcium concentration and calcium antagonist is considered as a promising drug that may alleviate...
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Therapeutic Effect of Nimodipine in Neonatal Rat Model of Cerebral Hypoxia-Ischemia

Hong IH, Kim HM

  • KMID: 2207695
  • J Korean Pediatr Soc.
  • 1999 Nov;42(11):1552-1558.
PURPOSE: Recent studies suggest that nimodipine, a potent calcium-channel blocker, may improve neurological outcome after experimental hypoxia-ischemic brain injury. This study was conducted to evaluate the therapeutic effect of nimodipine...
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Continuous nimodipine infusion during mitral valvuloplasty for infective endocarditis after mycotic cerebral aneurysmal clipping: A case report

Sung TY, Kim SH, Yi J, Kim HY, Kwon WK, Kim DK, Yoon TG, Kim TY

  • KMID: 1971001
  • Anesth Pain Med.
  • 2010 Jul;5(3):231-235.
We describe a patient with infective endocarditis (IE) complicated by mycotic cerebral aneurysms (MCAs). Transarterial embolization of a larger MCA was attempted but failed. Aneurysmal clipping through craniotomy was followed...
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The Effect of Nimodipine on Experimental Spinal Cord Injury

Cho TH, Park YK, Chong YK, Jeong HS, Suh JK, Lee HK, Lee KC, Chu JW

  • KMID: 2187749
  • J Korean Neurosurg Soc.
  • 1990 Sep;19(8-9):1184-1197.
Nimodipine the potent, centrally active, clacium channel blocker, is known to increase cerebral and spinal blood flow. In the present study, the authors investigated the effect on Nimodipine on injured...
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Effect of Nimodipine on Incomplete Global Cerebral Ischemia-Reperfusion with prior Hyperglycemia: in vivo 31P Magnetic Resonance Spectroscopic Study in Cats

Park PH, Lee YM, Choi JM

In vivo 31P magnetic resonance spectroscopy (MRS) was used to evaluate the effect of nimodipine on changes of [H] (pH) and the ratio of [PCr]/[Pi] in cats subjected to an...
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Effects of Nimodipine Treatment on Aneurysmal Subarachnoid Hemorrhage

Lee SY, Choi CH

  • KMID: 2018999
  • J Korean Neurosurg Soc.
  • 1997 Apr;26(4):555-562.
Nimodipine, a potent, central active, calcium channel blocker, is known to relieve vasospasm, increase cerebral blood flow(CBF) and affect positively on clinical outcome in patients with subarachnoid hemorrhage. Experimentally, the...
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Outcome of Nimodipine Treatment on the Surgical Cases of Aneurysmal Subarachnoid Hemorrhage

Lee SH, Han DH

  • KMID: 2044426
  • J Korean Neurosurg Soc.
  • 1994 Nov;23(11):1299-1309.
In order to elucidate the clinical effectiveness of nimodipine treatment, we analyzed 322 consecutive patients with the aneurysmal subarachnoid hemorrhage operated between September, 1987 and December, 1991. The nimodipine treatment...
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